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The approach was to inflate an occluder cuff on the terminal aorta for 30 s in one of two modes of ventricular pacing in five awake dogs with atrioventricular block and autonomic blockade. In one trial, cardiac output was maintained constant, meaning cuff inflation caused a portion of terminal aortic flow (a noncompliant circulation) to be diverted to the splanchnic and skin circulations (compliant circulations). In the other trial, arterial pressure was maintained constant, meaning blood flow to these other regions did not change. The response of right atrial pressure (corrected for differences in arterial pressure between the two trials) fit our hypothesis, being lower when blood flow was diverted to compliant regions. We conclude that a small (4% of cardiac output) diversion of blood flow from a noncompliant region to a compliant region reduces right atrial pressure by 0.7 mmHg.<\/jats:p>","DOI":"10.1152\/ajpheart.00482.2005","type":"journal-article","created":{"date-parts":[[2005,12,22]],"date-time":"2005-12-22T23:18:19Z","timestamp":1135293499000},"page":"H217-H223","source":"Crossref","is-referenced-by-count":4,"title":["Diversion of blood flow from noncompliant to compliant vasculature in awake dogs: mechanical impact on right atrial pressure"],"prefix":"10.1152","volume":"290","author":[{"given":"Terese M.","family":"Zidon","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Don D.","family":"Sheriff","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"24","reference":[{"key":"R1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1935.sp003301"},{"key":"R2","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.55.4.440"},{"key":"R3","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00868.2002"},{"key":"R4","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.31.1.105"},{"key":"R5","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.1993.265.2.H616"},{"key":"R6","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.34.5.606"},{"key":"R7","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.1990.259.6.H1796"},{"key":"R8","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.1992.263.6.H1755"},{"key":"R9","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1999.86.3.799"},{"key":"R10","doi-asserted-by":"crossref","unstructured":"Green JFand Jackman AP.Peripheral limitations to exercise.Med Sci Sports Exer16: 299\u2013305, 1984.","DOI":"10.1249\/00005768-198406000-00018"},{"key":"R11","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.1991.260.3.H752"},{"key":"R12","unstructured":"Janicki JS, Sheriff DD, Robotham JL, and Wise RA.Cardiac output during exercise: contributions of the cardiac, circulatory, and respiratory systems. 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