{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T18:33:45Z","timestamp":1773858825578,"version":"3.50.1"},"reference-count":44,"publisher":"American Physiological Society","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American Journal of Physiology-Heart and Circulatory Physiology"],"published-print":{"date-parts":[[2011,10]]},"abstract":"<jats:p> There are important differences in autonomic function and cardiovascular responsiveness between African Americans (AA) and Caucasian Americans (CA). This study tested the hypothesis that carotid baroreflex (CBR) responsiveness is impaired in normotensive AA compared with normotensive CA at rest. CBR control of heart rate (HR) and mean arterial blood pressure (MAP) was assessed in 30 nonhypertensive male subjects (15 AA; 15 CA; age 18\u201333 yr) with 5-s periods of neck pressure (NP; simulated hypotension) and neck suction (NS; simulated hypertension) ranging from +45 to \u221280 Torr during rest. Carotid-cardiac stimulus-response curves revealed a significantly lower minimum HR response in the CA compared with AA (40.8 \u00b1 2.4 vs. 49.8 \u00b1 2.9 beats\/min, respectively; P &lt; 0.05). In addition, the magnitude of the mean HR response to all trials of NS (\u221220, \u221240, \u221260, and \u221280 Torr) was attenuated in the AA group (AA, \u221210.1 \u00b1 1.7 vs. CA, \u221214.9 \u00b1 2.2 beats\/min; P &lt; 0.05), while no significant differences were found in the magnitude of the mean HR response to NP (+15, +30, and +45 Torr) between racial groups. There were no significant differences in the carotid-vasomotor stimulus-response curves between racial groups. Also, while no racial differences were found in the magnitude of the mean MAP response to all trials of NS, the magnitude of the mean MAP response to all trials of NP was attenuated in the AA group (AA, 7.2 \u00b1 1.3 vs. CA, 9.3 \u00b1 1.1 mmHg; P &lt; 0.05). Together, these findings support inherent differences in short-term blood pressure regulation between racial groups that exhibit different relative risk for the development of hypertension. <\/jats:p>","DOI":"10.1152\/ajpheart.00604.2011","type":"journal-article","created":{"date-parts":[[2011,8,13]],"date-time":"2011-08-13T02:32:08Z","timestamp":1313202728000},"page":"H1639-H1645","source":"Crossref","is-referenced-by-count":19,"title":["Carotid baroreflex responsiveness is impaired in normotensive African American men"],"prefix":"10.1152","volume":"301","author":[{"given":"Seth W.","family":"Holwerda","sequence":"first","affiliation":[{"name":"Department of Kinesiology and Center for Healthy Living and Longevity, University of Texas at Arlington, Arlington, Texas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diana","family":"Fulton","sequence":"additional","affiliation":[{"name":"Department of Kinesiology and Center for Healthy Living and Longevity, University of 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