{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T09:18:04Z","timestamp":1772961484981,"version":"3.50.1"},"reference-count":41,"publisher":"American Physiological Society","issue":"2","funder":[{"DOI":"10.13039\/100000050","name":"HHS | NIH | National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["HL123301"],"award-info":[{"award-number":["HL123301"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"HHS | NIH | National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["HL007736"],"award-info":[{"award-number":["HL007736"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"HHS | NIH | National Cancer Institute","doi-asserted-by":"publisher","award":["2P30CA118100"],"award-info":[{"award-number":["2P30CA118100"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.physiology.org"],"crossmark-restriction":true},"short-container-title":["American Journal of Physiology-Heart and Circulatory Physiology"],"published-print":{"date-parts":[[2021,2,1]]},"abstract":"<jats:p> These results suggest that CSE\u2019s protective role in the vasculature is impaired by simulated sleep apnea, which also upregulates CSE in the carotid body. Thus, this enzyme system can exert both pro- and antihypertensive effects and may contribute to elevated SNS outflow in sleep apnea. <\/jats:p>","DOI":"10.1152\/ajpheart.00672.2019","type":"journal-article","created":{"date-parts":[[2020,12,4]],"date-time":"2020-12-04T18:51:21Z","timestamp":1607107881000},"page":"H511-H519","update-policy":"https:\/\/doi.org\/10.1152\/aps-crossmark-policy","source":"Crossref","is-referenced-by-count":9,"title":["Simulated sleep apnea alters hydrogen sulfide regulation of blood flow and pressure"],"prefix":"10.1152","volume":"320","author":[{"given":"Adelaeda","family":"Barrera","sequence":"first","affiliation":[{"name":"Vascular Physiology Group, Department of Cell Biology and Physiology, School of Medicine, University of New Mexico, Albuquerque, New Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Humberto","family":"Morales-Loredo","sequence":"additional","affiliation":[{"name":"Vascular Physiology Group, Department of Cell Biology and Physiology, School of Medicine, University of New Mexico, Albuquerque, New Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joshua M.","family":"Garcia","sequence":"additional","affiliation":[{"name":"Vascular Physiology Group, Department of Cell Biology and Physiology, School of Medicine, University of New Mexico, Albuquerque, New Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gisel","family":"Fregoso","sequence":"additional","affiliation":[{"name":"Vascular Physiology Group, Department of Cell Biology and Physiology, School of Medicine, University of New Mexico, Albuquerque, New Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carolyn E.","family":"Pace","sequence":"additional","affiliation":[{"name":"Vascular Physiology Group, Department of Cell Biology and Physiology, School of Medicine, University of New Mexico, Albuquerque, New Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Perenkita J.","family":"Mendiola","sequence":"additional","affiliation":[{"name":"Vascular Physiology Group, Department of Cell Biology and Physiology, School of Medicine, University of New Mexico, Albuquerque, New Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5725-4664","authenticated-orcid":false,"given":"Jay S.","family":"Naik","sequence":"additional","affiliation":[{"name":"Vascular Physiology Group, Department of Cell Biology and Physiology, School of Medicine, University of New Mexico, Albuquerque, New Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura V.","family":"Gonzalez Bosc","sequence":"additional","affiliation":[{"name":"Vascular Physiology Group, Department of Cell Biology and Physiology, School of Medicine, University of New Mexico, Albuquerque, New Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9028-4021","authenticated-orcid":false,"given":"Nancy L.","family":"Kanagy","sequence":"additional","affiliation":[{"name":"Vascular Physiology Group, Department of Cell Biology and Physiology, School of Medicine, University of New Mexico, Albuquerque, New Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"24","reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1124\/pr.117.014050"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cellsig.2013.07.010"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1016\/j.niox.2017.10.010"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.116.08964"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00303.2019"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.110.228999"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1089\/met.2012.0045"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2008.05.002"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.91477.2007"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1016\/j.vph.2013.11.001"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00952.2015"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1016\/j.steroids.2017.12.006"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1080\/10739680801891348"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.37.2.511"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.3892\/ijmm.2016.2771"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00179.2015"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00506.2012"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00592.2013"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-36159-9"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1113\/JP275804"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00770.2003"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1113\/expphysiol.2013.073700"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00529.2011"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00444.2012"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2010.200691"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.00100.2012"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1005866107"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.00329.2016"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.0000153794.52852.04"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2010.10.087"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00341.2010"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00132.2008"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00219.2007"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.1124\/jpet.112.195412"},{"key":"B35","doi-asserted-by":"publisher","DOI":"10.1111\/j.1582-4934.2009.00929.x"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.1126\/scisignal.2005846"},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.1369\/jhc.6A7079.2006"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2006.02.082"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.1016\/j.npep.2018.12.004"},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.1126\/scisignal.aaf3204"},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2011.01.025"}],"container-title":["American Journal of Physiology-Heart and Circulatory Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.physiology.org\/doi\/pdf\/10.1152\/ajpheart.00672.2019","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,6,23]],"date-time":"2021-06-23T09:40:22Z","timestamp":1624441222000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.physiology.org\/doi\/10.1152\/ajpheart.00672.2019"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2,1]]},"references-count":41,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,2,1]]}},"alternative-id":["10.1152\/ajpheart.00672.2019"],"URL":"https:\/\/doi.org\/10.1152\/ajpheart.00672.2019","relation":{},"ISSN":["0363-6135","1522-1539"],"issn-type":[{"value":"0363-6135","type":"print"},{"value":"1522-1539","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,2,1]]},"assertion":[{"value":"2019-11-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-10-20","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-11-16","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-01-25","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}