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ET\n                    <jats:sub>B<\/jats:sub>\n                    R-mediated vasodilation is lost in postmenopausal women, but the effect of exogenous estradiol administration on ET\n                    <jats:sub>B<\/jats:sub>\n                    R function in postmenopausal women is not known. During estradiol administration, ET\n                    <jats:sub>B<\/jats:sub>\n                    R blockade did not affect cutaneous microvascular vasodilatory response to local heating. 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