{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T21:14:43Z","timestamp":1793222083766,"version":"4.5.0"},"reference-count":46,"publisher":"American Physiological Society","issue":"3","license":[{"start":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T00:00:00Z","timestamp":1768176000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":["journals.physiology.org"],"crossmark-restriction":true},"short-container-title":["American Journal of Physiology-Heart and Circulatory Physiology"],"published-print":{"date-parts":[[2026,3,1]]},"abstract":"<jats:p>This study provides the first evidence that maternal cardiovascular maladaptation in preeclampsia is directly mirrored in neonatal hemodynamics. Newborns displayed a compensatory rise in cardiac output in response to maternal systolic dysfunction, whereas changes in neonatal vascular tone remained minimal. Although maternal and neonatal circulations are traditionally examined independently, these findings underscore a tightly linked maternal-fetal hemodynamic dyad, offering new insight into the physiological continuity that spans the perinatal transition.<\/jats:p>","DOI":"10.1152\/ajpheart.00945.2025","type":"journal-article","created":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T16:50:07Z","timestamp":1768236607000},"page":"H708-H716","update-policy":"https:\/\/doi.org\/10.1152\/aps-crossmark-policy","source":"Crossref","is-referenced-by-count":5,"title":["Linking maternal and neonatal circulation in preeclampsia"],"prefix":"10.1152","volume":"330","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3338-1172","authenticated-orcid":false,"given":"Federica","family":"Piani","sequence":"first","affiliation":[{"name":"Medical University of Graz","place":["Austria"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-1388-3065","authenticated-orcid":false,"given":"Lorenzo","family":"Annesi","sequence":"additional","affiliation":[{"name":"University of Bologna","place":["Italy"]},{"name":"IRCCS Azienda Ospedaliero-Universitaria di Bologna","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Degli Esposti","sequence":"additional","affiliation":[{"name":"IRCCS Azienda Ospedaliero-Universitaria di Bologna","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sofia","family":"Vincenzi","sequence":"additional","affiliation":[{"name":"University of Bologna","place":["Italy"]},{"name":"IRCCS Azienda Ospedaliero-Universitaria di Bologna","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"De Crescenzo","sequence":"additional","affiliation":[{"name":"IRCCS Azienda Ospedaliero-Universitaria di Bologna","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna Nunzia","family":"Della Gatta","sequence":"additional","affiliation":[{"name":"University of Bologna","place":["Italy"]},{"name":"Morgagni Pierantoni Hospital","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuliana","family":"Simonazzi","sequence":"additional","affiliation":[{"name":"University of Bologna","place":["Italy"]},{"name":"IRCCS Azienda Ospedaliero-Universitaria di Bologna","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luigi","family":"Corvaglia","sequence":"additional","affiliation":[{"name":"University of Bologna","place":["Italy"]},{"name":"IRCCS Azienda Ospedaliero-Universitaria di Bologna","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2078-7114","authenticated-orcid":false,"given":"Silvia","family":"Martini","sequence":"additional","affiliation":[{"name":"University of Bologna","place":["Italy"]},{"name":"IRCCS Azienda Ospedaliero-Universitaria di Bologna","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"24","reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1016\/j.preghy.2021.03.001"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1080\/14767058.2019.1702943"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000437382.03963.88"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1186\/s12884-019-2617-8"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpobgyn.2016.05.005"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(14)60696-6"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1016\/bs.apha.2016.04.008"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2023.1144170"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.118.11191"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-022-06635-9"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1002\/uog.17516"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.110.162321"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2024.1415727"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.3390\/nu14235121"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1002\/uog.23521"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2021.625726"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2019.07.025"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacadv.2022.100059"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCIMAGING.116.005270"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.116.003906"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.3390\/biom11111625"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1016\/j.preghy.2021.09.008"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1093\/ehjci\/jex244"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2019.00482"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0287245"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1002\/uog.26121"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1016\/j.preghy.2012.04.163"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1111\/jch.14176"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2017.01.040"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1038\/s41390-025-04194-8"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.1002\/uog.5386"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.5041\/RMMJ.10379"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1111\/aogs.15072"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.1159\/000484315"},{"key":"B35","doi-asserted-by":"publisher","DOI":"10.3109\/14767058.2015.1085013"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.1080\/14767058.2016.1270935"},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2023.05.008"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.111.172387"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.1016\/j.echo.2021.01.008"},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2021.643926"},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.124.034494"},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2022.04.027"},{"key":"B43","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpobgyn.2025.102618"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.1186\/s13293-020-00299-3"},{"key":"B45","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-025-16346-1"},{"key":"B46","doi-asserted-by":"publisher","DOI":"10.1097\/HJH.0000000000003739"}],"container-title":["American Journal of Physiology-Heart and Circulatory Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.physiology.org\/doi\/pdf\/10.1152\/ajpheart.00945.2025","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T14:00:04Z","timestamp":1774533604000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.physiology.org\/doi\/10.1152\/ajpheart.00945.2025"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,1]]},"references-count":46,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,3,1]]}},"alternative-id":["10.1152\/ajpheart.00945.2025"],"URL":"https:\/\/doi.org\/10.1152\/ajpheart.00945.2025","relation":{},"ISSN":["0363-6135","1522-1539"],"issn-type":[{"value":"0363-6135","type":"print"},{"value":"1522-1539","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,1]]},"assertion":[{"value":"2025-12-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-12-22","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-02","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-13","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}