{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T19:46:03Z","timestamp":1776973563965,"version":"3.51.4"},"reference-count":52,"publisher":"American Physiological Society","issue":"4","content-domain":{"domain":["journals.physiology.org"],"crossmark-restriction":true},"short-container-title":["American Journal of Physiology-Lung Cellular and Molecular Physiology"],"published-print":{"date-parts":[[2026,4,1]]},"abstract":"<jats:p>Following its inhalation, coal dust disrupts the homeostasis of iron in lung cells to decrease availability. This occurs through a complexation, or binding, of the cell\u2019s required iron by the coal dust. The decreased iron concentrations available to the cell initiate inflammatory and fibrotic lung injuries, with the latter recognized as coal workers\u2019 pneumoconiosis.<\/jats:p>","DOI":"10.1152\/ajplung.00156.2025","type":"journal-article","created":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T11:40:44Z","timestamp":1771674044000},"page":"L434-L445","update-policy":"https:\/\/doi.org\/10.1152\/aps-crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Coal dust complexes host cell iron to impact metal homeostasis and pneumoconiosis"],"prefix":"10.1152","volume":"330","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0502-6448","authenticated-orcid":false,"given":"Andrew J.","family":"Ghio","sequence":"first","affiliation":[{"name":"US Environmental Protection Agency","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joleen M.","family":"Soukup","sequence":"additional","affiliation":[{"name":"US Environmental Protection Agency","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lisa A.","family":"Dailey","sequence":"additional","affiliation":[{"name":"US Environmental Protection Agency","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rahul G.","family":"Sangani","sequence":"additional","affiliation":[{"name":"West Virginia University","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9598-3369","authenticated-orcid":false,"given":"Elizabeth N.","family":"Pavlisko","sequence":"additional","affiliation":[{"name":"Duke University Medical Center","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victor L.","family":"Roggli","sequence":"additional","affiliation":[{"name":"Duke University Medical Center","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"24","reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201301-0042CI"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1038\/227445a0"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1136\/oem.36.3.206"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.2307\/3430516"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2020.02.007"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1021\/j100786a007"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.1994.267.2.L173"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrestox.5b00270"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1136\/oem.29.2.160"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-94949-0"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.3390\/su13168969"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1021\/es900173w"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1021\/jp212226j"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.4319\/lo.1968.13.4.0598"},{"key":"B15","first-page":"671","volume":"16","author":"Erdogan S","year":"2007","journal-title":"Polish J Environ Stud"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1016\/j.pupt.2011.07.001"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1016\/j.taap.2013.11.002"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.00099.2013"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1007\/BF02796396"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.3346\/jkms.2015.30.2.140"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1080\/09593330.2012.692716"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1016\/s0014-5793(01)03189-1"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1080\/17435390.2017.1398357"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrestox.0c00036"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1177\/0192623320961017"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1007\/s12517-021-09419-8"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1615\/JEnvironPatholToxicolOncol.2020036292"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.3390\/cells12212519"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2017-02-768580"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1080\/10715762.2023.2191813"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.1016\/j.abb.2023.109737"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2018.02014"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1007\/s13105-016-0529-x"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-3054.1983.tb00757.x"},{"key":"B35","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.89.9.3869"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.1016\/s0013-9351(05)80127-6"},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.1021\/es048766c"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.1165\/rcmb.2003-0070OC"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm\/136.6.1429"},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm\/140.6.1674"},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.1080\/00984100290071360"},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.1002\/jcb.21367"},{"key":"B43","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2407-7-176"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.1007\/s12011-015-0295-6"},{"key":"B45","doi-asserted-by":"publisher","DOI":"10.1007\/s11064-022-03611-2"},{"key":"B46","doi-asserted-by":"publisher","DOI":"10.1164\/arrd.1976.113.4.531"},{"key":"B47","first-page":"375","volume":"103","author":"Pathology standards for coal workers' pneumoconiosis","year":"1979","journal-title":"Arch Pathol Lab Med"},{"key":"B48","doi-asserted-by":"publisher","DOI":"10.1080\/03630269.2022.2083970"},{"key":"B49","doi-asserted-by":"publisher","DOI":"10.1002\/ajim.20418"},{"key":"B50","doi-asserted-by":"publisher","DOI":"10.1378\/chest.12-2085"},{"key":"B51","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-92587-0"},{"key":"B52","volume-title":"Black Lung: Anatomy of a Public Health Disaster","author":"Derickson A","year":"1998"}],"container-title":["American Journal of Physiology-Lung Cellular and Molecular Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.physiology.org\/doi\/pdf\/10.1152\/ajplung.00156.2025","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T19:30:11Z","timestamp":1776972611000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.physiology.org\/doi\/10.1152\/ajplung.00156.2025"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,1]]},"references-count":52,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,4,1]]}},"alternative-id":["10.1152\/ajplung.00156.2025"],"URL":"https:\/\/doi.org\/10.1152\/ajplung.00156.2025","relation":{},"ISSN":["1040-0605","1522-1504"],"issn-type":[{"value":"1040-0605","type":"print"},{"value":"1522-1504","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,1]]},"assertion":[{"value":"2025-05-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-11","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-07","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-27","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}