{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T12:12:30Z","timestamp":1790338350184,"version":"4.1.0"},"reference-count":51,"publisher":"American Physiological Society","issue":"2","funder":[{"DOI":"10.13039\/501100000038","name":"Gouvernement du Canada | Natural Sciences and Engineering Research Council of Canada (Conseil de Recherches en Sciences Naturelles et en G\u00e9nie du Canada)","doi-asserted-by":"publisher","award":["386143-2010"],"award-info":[{"award-number":["386143-2010"]}],"id":[{"id":"10.13039\/501100000038","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American Journal of Physiology-Regulatory, Integrative and Comparative Physiology"],"published-print":{"date-parts":[[2017,8,1]]},"abstract":"<jats:p> Some studies have observed a functional relationship between sweating and skin blood flow. However, the implications of this relationship during physiologically relevant conditions remain unclear. We manipulated sudomotor activity through changes in sweating efficiency to determine if parallel changes in vasomotor activity are observed. Eight young men completed two trials at 36\u00b0C and two trials at 42\u00b0C. During these trials, air temperature remained constant while ambient vapor pressure increased from 1.6 to 5.6 kPa over 2 h. Forced airflow across the skin was used to create conditions of high (HiS<jats:sub>eff<\/jats:sub>) or low (LoS<jats:sub>eff<\/jats:sub>) sweating efficiency. Local sweat rate (LSR), local skin blood flow (SkBF), as well as mean skin and esophageal temperatures were measured continuously. It took longer for LSR to increase during HiS<jats:sub>eff<\/jats:sub> at 36\u00b0C (HiS<jats:sub>eff<\/jats:sub>: 99\u2009\u00b1\u200911 vs. LoS<jats:sub>eff<\/jats:sub>: 77\u2009\u00b1\u200911 min, P &lt; 0.01) and 42\u00b0C (HiS<jats:sub>eff<\/jats:sub>: 72\u2009\u00b1\u200916 vs. LoS<jats:sub>eff<\/jats:sub>: 51\u2009\u00b1\u200915 min, P &lt; 0.01). In general, an increase in LSR preceded the increase in SkBF when expressed as ambient vapor pressure and time for all conditions ( P &lt; 0.05). However, both responses were activated at a similar change in mean body temperature (average across all trials, LSR: 0.26\u2009\u00b1\u20090.15 vs. SkBF: 0.30\u2009\u00b1\u20090.18\u00b0C, P = 0.26). These results demonstrate that altering the point at which LSR is initiated during heat exposure is paralleled by similar shifts for the increase in SkBF. However, local sweat production occurs before an increase in SkBF, suggesting that SkBF is not necessarily a prerequisite for sweating. <\/jats:p>","DOI":"10.1152\/ajpregu.00033.2017","type":"journal-article","created":{"date-parts":[[2017,5,31]],"date-time":"2017-05-31T20:20:12Z","timestamp":1496262012000},"page":"R140-R148","source":"Crossref","is-referenced-by-count":13,"title":["Sustained increases in skin blood flow are not a prerequisite to initiate sweating during passive heat exposure"],"prefix":"10.1152","volume":"313","author":[{"given":"Nicholas","family":"Ravanelli","sequence":"first","affiliation":[{"name":"Faculty of Health Sciences, University of Ottawa, Ottawa, Ontario, Canada;"},{"name":"Thermal Ergonomics Laboratory, Faculty of Health Sciences, University of Sydney, Sydney, 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