{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,9]],"date-time":"2023-09-09T15:55:21Z","timestamp":1694274921082},"reference-count":32,"publisher":"American Physiological Society","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American Journal of Physiology-Regulatory, Integrative and Comparative Physiology"],"published-print":{"date-parts":[[2005,8]]},"abstract":"<jats:p>Surgical removal of body fat (lipectomy) triggers compensatory increases in nonexcised white adipose tissue (WAT), thus restoring adiposity levels in many species, including Siberian hamsters. In Siberian hamsters, when their lipectomized WAT is transplanted to another site (autologous grafts, no net change in body fat), healthy grafts result, but the lipectomy-induced compensatory increases in nonexcised WAT masses are exaggerated, an effect that apparently occurs only when the grafts contact intact WAT. When WAT is added to nonlipectomized hamsters to increase body fat, native WAT pads do not decrease. Thus WAT addition or removal-replacement does not induce compensatory WAT responses consistent with total body fat regulation as does WAT subtraction. Therefore, we tested whether the exaggerated response to lipectomy occurring with autologous WAT transplantation is dependent on graft site placement and whether the donor graft source [inguinal or epididymal WAT (IWAT, EWAT), sibling vs. nonsibling] affected body fat responses to WAT additions in nonlipectomized hamsters. Lipectomized hamsters received subcutaneous autologous EWAT grafts placed remotely from other WAT (ventrum) or in contact with intact WAT (dorsum), whereas intact hamsters received EWAT or IWAT grafts from sibling or nonsibling donors. The exaggerated response to lipectomy only occurred when grafts were in contact with intact WAT. EWAT, but not IWAT, additions to nonlipectomized siblings or nonsiblings increased native IWAT and retroperitoneal WAT mass but not EWAT mass compared with controls. Collectively, WAT transplantation to either lipectomized or nonlipectomized hamsters increased body fat contingent on graft contact with intact or native WAT.<\/jats:p>","DOI":"10.1152\/ajpregu.00116.2005","type":"journal-article","created":{"date-parts":[[2005,4,1]],"date-time":"2005-04-01T01:37:24Z","timestamp":1112319444000},"page":"R380-R388","source":"Crossref","is-referenced-by-count":16,"title":["Effects of white adipose tissue grafts on total body fat and cellularity are dependent on graft type and location"],"prefix":"10.1152","volume":"289","author":[{"given":"Eva L.","family":"Lacy","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Timothy J.","family":"Bartness","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"24","reference":[{"key":"R1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.1998.275.1.R291"},{"key":"R2","doi-asserted-by":"publisher","DOI":"10.1113\/expphysiol.1937.sp000731"},{"key":"R3","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00558.2003"},{"key":"R4","doi-asserted-by":"crossref","unstructured":"Cantu RCand Goodman HM.Effects of denervation and fasting on white adipose tissue.Am J Physiol212: 207\u2013212, 1967.","DOI":"10.1152\/ajplegacy.1967.212.1.207"},{"key":"R5","doi-asserted-by":"publisher","DOI":"10.1016\/0026-0495(74)90110-3"},{"key":"R6","doi-asserted-by":"publisher","DOI":"10.1210\/endo.133.5.8404678"},{"key":"R7","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.2001.281.5.R1499"},{"key":"R8","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.2000.278.6.R1401"},{"key":"R9","unstructured":"Ellenbogen R.Fat transfer: current use in practice.Clin Plast Surg27: 545\u2013556, 2000."},{"key":"R10","unstructured":"Faust IM.Role of the fat cell in energy balance physiology. In:Eating and Its Disorders, edited by Stunkard AJ and Stellar E. New York: Raven, 1984, p. 97\u2013107."},{"key":"R11","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.1987.253.6.R942"},{"key":"R12","doi-asserted-by":"publisher","DOI":"10.1007\/BF02284791"},{"key":"R13","doi-asserted-by":"publisher","DOI":"10.1096\/fasebj.4.15.2253845"},{"key":"R14","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00339.2002"},{"key":"R15","unstructured":"Hausman DB, Bartness TJ, DiGirolamo M, Fine JB, Plunkett SS, and Martin RJ.Proliferative activity of adipose tissue conditioned media correlates with fat cell size in animal models of obesity.Adipocytes1:25\u201333, 2005."},{"key":"R16","doi-asserted-by":"publisher","DOI":"10.1046\/j.1467-789X.2001.00042.x"},{"key":"R17","doi-asserted-by":"crossref","unstructured":"Hirsch Jand Gallian E.Methods for the determination of adipose cell size in man and animals.J Lipid Res9: 110\u2013119, 1968.","DOI":"10.1016\/S0022-2275(20)43151-7"},{"key":"R18","doi-asserted-by":"publisher","DOI":"10.1098\/rspb.1953.0009"},{"key":"R19","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00476.2003"},{"key":"R20","doi-asserted-by":"publisher","DOI":"10.1016\/S0031-9384(97)00233-3"},{"key":"R21","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.1994.266.3.R870"},{"key":"R22","doi-asserted-by":"crossref","unstructured":"Mauer MMand Bartness TJ.A role for testosterone in the maintenance of seasonally-appropriate body mass, but not in lipectomy-induced body fat compensation in Siberian hamsters.Obes Res3: 31\u201341, 1995.","DOI":"10.1002\/j.1550-8528.1995.tb00118.x"},{"key":"R23","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.1997.273.6.R2117"},{"key":"R24","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.1997.272.1.R68"},{"key":"R25","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.1996.270.2.R383"},{"key":"R26","doi-asserted-by":"publisher","DOI":"10.1016\/S0149-7634(00)00047-6"},{"key":"R27","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-3940(99)00054-3"},{"key":"R28","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00634.2003"},{"key":"R29","doi-asserted-by":"publisher","DOI":"10.1016\/j.physbeh.2004.02.023"},{"key":"R30","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.00295.2004"},{"key":"R31","doi-asserted-by":"publisher","DOI":"10.1126\/science.280.5368.1378"},{"key":"R32","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.1998.275.5.R1488"}],"container-title":["American Journal of Physiology-Regulatory, Integrative and Comparative Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.physiology.org\/doi\/pdf\/10.1152\/ajpregu.00116.2005","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,7]],"date-time":"2021-07-07T15:48:26Z","timestamp":1625672906000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.physiology.org\/doi\/10.1152\/ajpregu.00116.2005"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,8]]},"references-count":32,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2005,8]]}},"alternative-id":["10.1152\/ajpregu.00116.2005"],"URL":"https:\/\/doi.org\/10.1152\/ajpregu.00116.2005","relation":{},"ISSN":["0363-6119","1522-1490"],"issn-type":[{"value":"0363-6119","type":"print"},{"value":"1522-1490","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,8]]}}}