{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T15:26:10Z","timestamp":1781277970578,"version":"3.54.1"},"reference-count":92,"publisher":"American Physiological Society","issue":"2","funder":[{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["1927616"],"award-info":[{"award-number":["1927616"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007810","name":"UNC | University of North Carolina Wilmington","doi-asserted-by":"publisher","award":["N\/A"],"award-info":[{"award-number":["N\/A"]}],"id":[{"id":"10.13039\/100007810","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.physiology.org"],"crossmark-restriction":true},"short-container-title":["American Journal of Physiology-Regulatory, Integrative and Comparative Physiology"],"published-print":{"date-parts":[[2024,2,1]]},"abstract":"<jats:p> This is the first study to determine the red blood cell lifespan in a marine mammal species. High concentrations of carbon monoxide (CO) were found in the blood of bottlenose dolphins and in the blood and breath of belugas compared with healthy humans. Red blood cell turnover accounted for these high levels in bottlenose dolphins, but there may be alternative mechanisms of endogenous CO production that are contributing to the CO concentrations observed in belugas. <\/jats:p>","DOI":"10.1152\/ajpregu.00172.2023","type":"journal-article","created":{"date-parts":[[2023,11,20]],"date-time":"2023-11-20T09:14:56Z","timestamp":1700471696000},"page":"R134-R146","update-policy":"https:\/\/doi.org\/10.1152\/aps-crossmark-policy","source":"Crossref","is-referenced-by-count":3,"title":["Relationship between red blood cell lifespan and endogenous carbon monoxide in the common bottlenose dolphin and beluga"],"prefix":"10.1152","volume":"326","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9526-5586","authenticated-orcid":false,"given":"Anna B.","family":"Pearson","sequence":"first","affiliation":[{"name":"Department of Biology and Marine Biology, University of North Carolina Wilmington, Wilmington, North Carolina, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2453-7350","authenticated-orcid":false,"given":"Luis A.","family":"H\u00fcckst\u00e4dt","sequence":"additional","affiliation":[{"name":"Department of Biology and Marine Biology, University of North Carolina Wilmington, Wilmington, North Carolina, United States"},{"name":"Centre for Ecology and Conservation, University of Exeter, Penryn, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2479-9617","authenticated-orcid":false,"given":"Stephen T.","family":"Kinsey","sequence":"additional","affiliation":[{"name":"Department of Biology and Marine Biology, University of North Carolina Wilmington, Wilmington, North Carolina, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Todd L.","family":"Schmitt","sequence":"additional","affiliation":[{"name":"SeaWorld Parks and Entertainment, San Diego, California, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8573-5070","authenticated-orcid":false,"given":"Todd R.","family":"Robeck","sequence":"additional","affiliation":[{"name":"SeaWorld Parks and Entertainment, San Diego, California, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6213-3429","authenticated-orcid":false,"given":"Judy","family":"St. Leger","sequence":"additional","affiliation":[{"name":"Cornell University College of Veterinary Medicine, Cornell University, Ithaca, New York, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1556-770X","authenticated-orcid":false,"given":"Paul J.","family":"Ponganis","sequence":"additional","affiliation":[{"name":"Scripps Institution of Oceanography, University of California San Diego, La Jolla, California, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0563-0509","authenticated-orcid":false,"given":"Michael S.","family":"Tift","sequence":"additional","affiliation":[{"name":"Department of Biology and Marine Biology, University of North Carolina Wilmington, Wilmington, North Carolina, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"24","reference":[{"key":"B1","first-page":"767","volume":"87","author":"Berk PD","year":"1976","journal-title":"J Lab Clin Med"},{"key":"B3","first-page":"273","volume-title":"Carbon Monoxide and Cardiovascular Functions","author":"Vreman H","year":"2002"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1172\/JCI104802"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1038\/jp.2014.66"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1172\/JCI2484"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.22504"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1974.36.1.49"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1172\/JCI105296"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1023\/a:1009982011226"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)56856-3"},{"key":"B12","first-page":"47","volume":"14","author":"Landaw SA","year":"1988","journal-title":"Blood Cells"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.1988.68.2.503"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1177\/003591576205501104"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1111\/j.1423-0410.1958.tb03617.x"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(17)35201-8"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2010.02926.x"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1084\/jem.29.3.267"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1016\/0304-4157(89)90006-3"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.2001.81.3.1353"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1016\/j.tracli.2006.02.017"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1007\/BF01870583"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1007\/s10522-019-09804-7"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1016\/0300-9629(81)92990-X"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2014.00084"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1159\/000089839"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbpa.2010.11.029"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1016\/s1532-0456(02)00075-3"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2010.00146"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2019.01199"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.1016\/j.jembe.2007.02.003"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1016\/s1095-6433(02)00253-2"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbpc.2010.02.007"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.1139\/z81-066"},{"key":"B35","doi-asserted-by":"publisher","DOI":"10.1111\/mms.12391"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2020.00886"},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.171.3.1572"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.1038\/74680"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.00360.2016"},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.1242\/jeb.100677"},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.1038\/183074a0"},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.1139\/z84-344"},{"key":"B43","doi-asserted-by":"publisher","DOI":"10.1017\/CBO9781139045490"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.1126\/science.151.3709.456"},{"key":"B45","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.23866"},{"key":"B46","doi-asserted-by":"publisher","DOI":"10.1007\/BF01965368"},{"key":"B47","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.21148"},{"key":"B48","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00174.2012"},{"key":"B49","doi-asserted-by":"publisher","DOI":"10.1159\/000357986"},{"key":"B50","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3148.2012.01139.x"},{"key":"B51","doi-asserted-by":"publisher","DOI":"10.1590\/s0100-879x1999000600003"},{"key":"B52","first-page":"81","volume":"33","author":"Kaymaz AA","year":"2005","journal-title":"Clin Hemorheol Microcirc"},{"key":"B53","doi-asserted-by":"publisher","DOI":"10.1006\/abio.1976.9999"},{"key":"B54","doi-asserted-by":"publisher","DOI":"10.1016\/j.zool.2008.06.001"},{"key":"B55","doi-asserted-by":"publisher","DOI":"10.1093\/clinchem\/30.8.1382"},{"key":"B56","doi-asserted-by":"publisher","DOI":"10.1016\/s0006-291x(02)02668-2"},{"key":"B57","doi-asserted-by":"publisher","DOI":"10.1016\/j.cccn.2004.06.005"},{"key":"B58","doi-asserted-by":"publisher","DOI":"10.1006\/bbrc.1998.8244"},{"key":"B59","doi-asserted-by":"publisher","DOI":"10.1378\/chest.125.6.2160"},{"key":"B60","doi-asserted-by":"publisher","DOI":"10.1080\/01652176.2020.1845415"},{"key":"B61","doi-asserted-by":"publisher","DOI":"10.1638\/2012-0172R"},{"key":"B62","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.56.7418"},{"key":"B63","doi-asserted-by":"publisher","DOI":"10.1053\/jhep.2003.50304"},{"key":"B64","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.1997.287"},{"key":"B65","doi-asserted-by":"publisher","DOI":"10.1644\/05-MAMM-A-365R1.1"},{"key":"B66","doi-asserted-by":"publisher","DOI":"10.1007\/s00360-011-0612-0"},{"key":"B67","doi-asserted-by":"publisher","DOI":"10.1578\/AM.40.4.2014.350"},{"key":"B68","doi-asserted-by":"publisher","DOI":"10.1242\/jeb.192211"},{"key":"B69","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00658.2016"},{"key":"B70","doi-asserted-by":"publisher","DOI":"10.1378\/chest.07-2904"},{"key":"B71","doi-asserted-by":"publisher","DOI":"10.1016\/s0091-6749(00)90075-7"},{"key":"B72","doi-asserted-by":"publisher","DOI":"10.1016\/s1095-6433(00)00182-3"},{"key":"B73","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbpa.2023.111438"},{"key":"B74","doi-asserted-by":"publisher","DOI":"10.1159\/000457630"},{"key":"B75","doi-asserted-by":"publisher","DOI":"10.1097\/00005176-198508000-00027"},{"key":"B76","doi-asserted-by":"publisher","DOI":"10.1128\/jb.112.3.1310-1315.1972"},{"key":"B77","doi-asserted-by":"publisher","DOI":"10.1038\/189510a0"},{"key":"B78","doi-asserted-by":"publisher","DOI":"10.2174\/1381612824666180723161811"},{"key":"B79","doi-asserted-by":"publisher","DOI":"10.1016\/0034-5687(83)90072-5"},{"key":"B80","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbpa.2016.12.013"},{"key":"B81","doi-asserted-by":"publisher","DOI":"10.1084\/jem.101.5.451"},{"key":"B82","doi-asserted-by":"publisher","DOI":"10.1126\/science.137.3531.673"},{"key":"B83","first-page":"917","volume":"20","author":"Cornelius CE","year":"1959","journal-title":"Am J Vet Res"},{"key":"B84","doi-asserted-by":"publisher","DOI":"10.1159\/000342524"},{"key":"B85","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1951.sp004530"},{"key":"B86","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2257.1998.00014.x"},{"key":"B87","first-page":"427","volume":"77","author":"Mafuvadze B","year":"2007","journal-title":"Veterinarski Arhiv"},{"key":"B88","doi-asserted-by":"publisher","DOI":"10.1660\/0022-8443(2006)109[149:COEOFA]2.0.CO;2"},{"key":"B89","doi-asserted-by":"publisher","DOI":"10.3233\/CH-2012-1546"},{"key":"B90","first-page":"57","volume":"43","author":"Castellini M","year":"2006","journal-title":"Biorheology"},{"key":"B91","doi-asserted-by":"publisher","DOI":"10.3109\/00365519109091645"},{"key":"B92","doi-asserted-by":"publisher","DOI":"10.1016\/j.plefa.2013.12.005"},{"key":"B93","doi-asserted-by":"publisher","DOI":"10.1016\/j.ab.2005.03.019"}],"container-title":["American Journal of Physiology-Regulatory, Integrative and Comparative Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.physiology.org\/doi\/pdf\/10.1152\/ajpregu.00172.2023","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,19]],"date-time":"2024-01-19T18:01:52Z","timestamp":1705687312000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.physiology.org\/doi\/10.1152\/ajpregu.00172.2023"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2,1]]},"references-count":92,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,2,1]]}},"alternative-id":["10.1152\/ajpregu.00172.2023"],"URL":"https:\/\/doi.org\/10.1152\/ajpregu.00172.2023","relation":{},"ISSN":["0363-6119","1522-1490"],"issn-type":[{"value":"0363-6119","type":"print"},{"value":"1522-1490","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,2,1]]},"assertion":[{"value":"2023-07-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-10-17","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-11-15","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-01-19","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}