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Experiments were performed on nine unanesthetized, chemo- and barodenervated, decerebrate adult rats, in which asphyxia elicited hyperpnea, followed by apnea and gasping. A gated fast Fourier transform (FFT) analysis and a novel time-frequency representation (TFR) analysis were developed and applied to whole phrenic and to medial branch hypoglossal nerve recordings. Our results revealed one MFO and one HFO peak in the phrenic output during eupnea, where HFO was prominent in the first two-thirds of the burst and MFO was prominent in the latter two-thirds of the burst. The hypoglossal activity contained broadband power distribution with several distinct peaks. During gasping, two high-amplitude MFO peaks were present in phrenic activity, and this state was characterized by a conspicuous loss in HFO power. Hypoglossal activity showed a significant reduction in power and a shift in its distribution toward lower frequencies during gasping. TFR analysis of phrenic activity revealed the increasing importance of an initial low-frequency \u201cstart-up\u201d burst that grew in relative intensity as hypoxic conditions persisted. Significant changes in MFO and HFO rhythm generation during the transition from eupnea to gasping presumably reflect a reconfiguration of the respiratory network and\/or alterations in signal processing by the circuitry associated with the two motor pools. <\/jats:p>","DOI":"10.1152\/ajpregu.00217.2006","type":"journal-article","created":{"date-parts":[[2006,7,7]],"date-time":"2006-07-07T00:44:56Z","timestamp":1152233096000},"page":"R1414-R1429","source":"Crossref","is-referenced-by-count":16,"title":["Selective loss of high-frequency oscillations in phrenic and hypoglossal activity in the decerebrate rat during gasping"],"prefix":"10.1152","volume":"291","author":[{"given":"Vitaliy","family":"Marchenko","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert F.","family":"Rogers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"24","reference":[{"key":"R1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(83)90299-8"},{"key":"R2","doi-asserted-by":"crossref","unstructured":"Akay M, Melton JE, Welkowitz W, Edelman NH, and Neubauer JA. 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