{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T14:43:47Z","timestamp":1791384227026,"version":"4.3.3"},"reference-count":58,"publisher":"American Physiological Society","issue":"11","funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science (JSPS)","doi-asserted-by":"publisher","award":["A-15H05361"],"award-info":[{"award-number":["A-15H05361"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American Journal of Physiology-Regulatory, Integrative and Comparative Physiology"],"published-print":{"date-parts":[[2015,12,1]]},"abstract":"<jats:p> Herein, we investigated the effects of passive heat stress on human somatosensory processing recorded by somatosensory-evoked potentials (SEPs). Fifteen healthy subjects received a median nerve stimulation at the left wrist under two thermal conditions: Heat Stress and normothermic Time Control. The latencies and amplitudes of P14, N20, P25, N35, P45, and N60 at C4\u2032 and P14, N18, P22, and N30 at Fz were evaluated. Under the Heat Stress condition, SEPs were recorded at normothermic baseline (1st), early in heat stress (2nd), when esophageal temperature had increased by \u223c1.0\u00b0C (3rd) and \u223c2.0\u00b0C (4th), and after heat stress (5th). In the Time Control condition, SEPs were measured at the same time intervals as those in the Heat Stress condition. The peak latencies and amplitudes of SEPs did not change early in heat stress. However, the latencies of P14, N20, and N60 at C4\u2032 and P14, N18, and P22 at Fz were significantly shorter in the 4th session than in the 1st session. Furthermore, the peak amplitudes of P25 and N60 at C4\u2032, and P22 and N30 at Fz decreased with increases in body temperature. On the other hand, under the Time Control condition, no significant differences were observed in the amplitudes or latencies of any component of SEPs. These results suggested that the conduction velocity of the ascending somatosensory input was accelerated by increases in body temperature, and hyperthermia impaired the neural activity of cortical somatosensory processing. <\/jats:p>","DOI":"10.1152\/ajpregu.00280.2015","type":"journal-article","created":{"date-parts":[[2015,10,14]],"date-time":"2015-10-14T23:39:28Z","timestamp":1444865968000},"page":"R1387-R1396","source":"Crossref","is-referenced-by-count":21,"title":["Effects of passive heat stress on human somatosensory processing"],"prefix":"10.1152","volume":"309","author":[{"given":"Hiroki","family":"Nakata","sequence":"first","affiliation":[{"name":"Department of Health Sciences, Faculty of Human Life and Environment, Nara Women's University, Nara, Japan; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Misaki","family":"Oshiro","sequence":"additional","affiliation":[{"name":"Graduate School of Humanities and Sciences, Nara Women's University, Nara, 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