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The salt appetite response was age dependent with \u201cmiddle-aged\u201d rats ingesting the most saline solution followed in order by young and then old rats. While old rats drank the least saline solution, the amounts of saline ingested still were copious and comprise an unambiguous demonstration of salt appetite in old rats. Middle-aged rats had the highest saline preference ratios of the groups under baseline conditions and throughout testing consistent with an increased avidity for sodium taste. There were age differences in renal handling of water and sodium that were consistent with a renal contribution to the greater saline intakes by middle-aged rats. There was evidence of impaired renal function in old rats, but this did not account for the reduced saline intakes of the oldest rats.<\/jats:p>","DOI":"10.1152\/ajpregu.00349.2013","type":"journal-article","created":{"date-parts":[[2013,10,17]],"date-time":"2013-10-17T04:20:33Z","timestamp":1381983633000},"page":"R1498-R1505","source":"Crossref","is-referenced-by-count":10,"title":["Effects of aging on mineralocorticoid-induced salt appetite in rats"],"prefix":"10.1152","volume":"305","author":[{"given":"Robert L.","family":"Thunhorst","sequence":"first","affiliation":[{"name":"Departments of 1Psychology,"},{"name":"Cardiovascular Center, University of Iowa, Iowa City, Iowa"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Terry G.","family":"Beltz","sequence":"additional","affiliation":[{"name":"Departments of 1Psychology,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alan 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