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Here, we extend the initial observations in several ways, including the fundamental demonstration that core body temperature (T<jats:sub>c<\/jats:sub>) drops substantially (about 1.5\u00b0C) in response to the light stimulation at CT15 or CT18 in a manner suggesting that the change is a direct response to light rather than simply a result of the locomotor suppression. The results show that 1) the decline of locomotion and T<jats:sub>c<\/jats:sub> begin soon after nocturnal light stimulation; 2) the variability in the magnitude and onset of light-induced locomotor suppression is very large, whereas the variability in T<jats:sub>c<\/jats:sub> is very small; 3) T<jats:sub>c<\/jats:sub> recovers from the light-induced decline in advance of the recovery of locomotion; 4) under entrained and freerunning conditions, the daily late afternoon T<jats:sub>c<\/jats:sub> increase occurs in advance of the corresponding increase in wheel running; and 5) toward the end of the subjective night, the nocturnally elevated T<jats:sub>c<\/jats:sub> persists longer than does locomotor activity. Finally, EEG measurements confirm light-induced sleep and, when T<jats:sub>c<\/jats:sub> or locomotion was measured, show their temporal association with sleep onset. Both EEG- and immobility-based sleep detection methods confirm rapid induction of light-induced sleep. The similarities between light-induced loss of locomotion and drop in T<jats:sub>c<\/jats:sub> suggest a common cause for parallel responses. The photosomnolence response may be contingent upon both the absence of locomotion and a simultaneous low T<jats:sub>c<\/jats:sub>. <\/jats:p>","DOI":"10.1152\/ajpregu.00460.2012","type":"journal-article","created":{"date-parts":[[2013,1,30]],"date-time":"2013-01-30T22:45:58Z","timestamp":1359585958000},"page":"R459-R471","source":"Crossref","is-referenced-by-count":29,"title":["Brief light stimulation during the mouse nocturnal activity phase simultaneously induces a decline in core temperature and locomotor activity followed by EEG-determined sleep"],"prefix":"10.1152","volume":"304","author":[{"given":"Keith M.","family":"Studholme","sequence":"first","affiliation":[{"name":"Department of Psychiatry, Stony Brook Medical Center, Stony Brook, New York;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heinrich S.","family":"Gompf","sequence":"additional","affiliation":[{"name":"Department of Neurology, Program in Neuroscience and Division of Sleep Medicine, Harvard 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