{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,24]],"date-time":"2025-09-24T09:44:33Z","timestamp":1758707073452},"reference-count":0,"publisher":"American Physiological Society","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American Journal of Physiology-Regulatory, Integrative and Comparative Physiology"],"published-print":{"date-parts":[[1992,8,1]]},"abstract":"<jats:p> Electrophysiological analysis of the neural control of the vas deferens was performed in urethan-anesthetized rats. Intraluminal distension (0.2 ml\/min) or electrical stimulation of hypogastric (threshold 1-5 V, 20 Hz) and pelvic nerves (2-5 V, 20 Hz) produced contractions of the vas deferens. Distension-evoked contractile activity was not abolished by nicotinic ganglionic blockade or ipsilateral hypogastric and pelvic nerve transection. Contractions following hypogastric nerve stimulation were abolished by prazosin, while pelvic nerve-evoked responses were partially blocked by atropine. Hypogastric nerve, pelvic nerve, and sympathetic chain stimulation evoked volleys with latencies of 10-30 ms in vasal nerves. Crude estimates for conduction velocities for these responses (less than 0.5 m\/s) corresponded to activation of unmyelinated C-fibers. Stimulation of the dorsal nerve of the penis (DNP) (10-16 V, 10-40 Hz) or administration of 5-methoxy-N,N-dimethyltryptamine, both of which produce seminal emission, elicited reflex discharges in nerves to the vas deferens. Hypogastric nerve but not pelvic nerve transection abolished both spontaneous and evoked (105- to 380-ms latency) reflex activity. These experiments provide insight into the organization of afferents in the DNP and efferents conveyed by autonomic pathways that regulate male reproduction. <\/jats:p>","DOI":"10.1152\/ajpregu.1992.263.2.r331","type":"journal-article","created":{"date-parts":[[2017,12,24]],"date-time":"2017-12-24T15:58:02Z","timestamp":1514131082000},"page":"R331-R338","source":"Crossref","is-referenced-by-count":6,"title":["Neural regulation of the vas deferens in the rat: an electrophysiological analysis"],"prefix":"10.1152","volume":"263","author":[{"given":"S. C.","family":"Kolbeck","sequence":"first","affiliation":[{"name":"Department of Urology, University of Virginia Health Sciences Center,Charlottesville 22908."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W. D.","family":"Steers","sequence":"additional","affiliation":[{"name":"Department of Urology, University of Virginia Health Sciences Center,Charlottesville 22908."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"24","container-title":["American Journal of Physiology-Regulatory, Integrative and Comparative Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.physiology.org\/doi\/pdf\/10.1152\/ajpregu.1992.263.2.R331","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,8]],"date-time":"2019-09-08T22:38:23Z","timestamp":1567982303000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.physiology.org\/doi\/10.1152\/ajpregu.1992.263.2.R331"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1992,8,1]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1992,8,1]]}},"alternative-id":["10.1152\/ajpregu.1992.263.2.R331"],"URL":"https:\/\/doi.org\/10.1152\/ajpregu.1992.263.2.r331","relation":{},"ISSN":["0363-6119","1522-1490"],"issn-type":[{"value":"0363-6119","type":"print"},{"value":"1522-1490","type":"electronic"}],"subject":[],"published":{"date-parts":[[1992,8,1]]}}}