{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T23:54:39Z","timestamp":1790639679496,"version":"4.1.0"},"reference-count":39,"publisher":"American Physiological Society","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American Journal of Physiology-Regulatory, Integrative and Comparative Physiology"],"published-print":{"date-parts":[[2002,1,1]]},"abstract":"<jats:p>Siberian hamsters exhibit seasonal fluctuations in white adipose tissue (WAT) mass, with peaks in long \u201csummerlike\u201d days (LDs) and nadirs in short \u201cwinterlike\u201d days (SDs). These responses can be mimicked in the laboratory after transfer from LDs to SDs. The purpose of the present study was to test whether changes in WAT and brown adipose tissue (BAT) gene expression that are mediated by the sympathetic nervous system in other obesity models are also associated with seasonal adiposity changes in Siberian hamsters. SDs decreased WAT mass and leptin mRNA, increased WAT \u03b2<jats:sub>3<\/jats:sub>-adrenoceptor mRNA, and induced retroperitoneal WAT uncoupling protein-1 mRNA (the latter measured by RT-PCR, others measured by ribonuclease protection assay) while increasing BAT uncoupling protein-1 and peroxisome proliferator-activated receptor-\u03b3 coactivator-1 mRNAs. These effects were not due to SD-induced gonadal regression and largely occurred before the usual SD-induced decreases in food intake. Thus the SD-induced decreased adiposity of Siberian hamsters may be due to a coordinated suite of WAT and BAT gene transcription changes ultimately increasing lipid mobilization and utilization.<\/jats:p>","DOI":"10.1152\/ajpregu.2002.282.1.r114","type":"journal-article","created":{"date-parts":[[2017,12,21]],"date-time":"2017-12-21T13:11:03Z","timestamp":1513861863000},"page":"R114-R121","source":"Crossref","is-referenced-by-count":34,"title":["Photoperiodic regulation of gene expression in brown and white adipose tissue of Siberian hamsters (<i>Phodopus sungorus<\/i>)"],"prefix":"10.1152","volume":"282","author":[{"given":"Gregory E.","family":"Demas","sequence":"first","affiliation":[{"name":"Center for Behavioral Neuroscience and"},{"name":"Department of Biology, Georgia State University, Atlanta, Georgia 30303;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert R.","family":"Bowers","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology 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