{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T19:07:42Z","timestamp":1778699262994,"version":"3.51.4"},"reference-count":54,"publisher":"American Physiological Society","issue":"6","funder":[{"DOI":"10.13039\/100000062","name":"HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases","doi-asserted-by":"publisher","award":["K08DK115833"],"award-info":[{"award-number":["K08DK115833"]}],"id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000062","name":"HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases","doi-asserted-by":"publisher","award":["R01DK137784"],"award-info":[{"award-number":["R01DK137784"]}],"id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100017618","name":"HHS | NIH | NIDDK | Division of Diabetes, Endocrinology, and Metabolic Diseases","doi-asserted-by":"publisher","award":["P30DK056336"],"award-info":[{"award-number":["P30DK056336"]}],"id":[{"id":"10.13039\/100017618","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100017618","name":"HHS | NIH | NIDDK | Division of Diabetes, Endocrinology, and Metabolic Diseases","doi-asserted-by":"publisher","award":["P30DK079626"],"award-info":[{"award-number":["P30DK079626"]}],"id":[{"id":"10.13039\/100017618","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100017618","name":"HHS | NIH | NIDDK | Division of Diabetes, Endocrinology, and Metabolic Diseases","doi-asserted-by":"publisher","award":["P30AG050886A"],"award-info":[{"award-number":["P30AG050886A"]}],"id":[{"id":"10.13039\/100017618","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100017618","name":"HHS | NIH | NIDDK | Division of Diabetes, Endocrinology, and Metabolic Diseases","doi-asserted-by":"publisher","award":["U54 DK137307"],"award-info":[{"award-number":["U54 DK137307"]}],"id":[{"id":"10.13039\/100017618","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100017618","name":"HHS | NIH | NIDDK | Division of Diabetes, Endocrinology, and Metabolic Diseases","doi-asserted-by":"publisher","award":["R01DK126774"],"award-info":[{"award-number":["R01DK126774"]}],"id":[{"id":"10.13039\/100017618","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.physiology.org"],"crossmark-restriction":true},"short-container-title":["American Journal of Physiology-Renal Physiology"],"published-print":{"date-parts":[[2026,6,1]]},"abstract":"<jats:p>Metabolic dysfunction-associated steatotic liver disease (MASLD) has been reported to lead to increased oxalate synthesis in mouse models. We show here that changes in oxalate synthesis, mediated by complex changes in enzymes involved in glyoxylate metabolism, are dependent on the degree of severity of MASLD, resulting in limited increases in urinary oxalate in mild MASLD, but marked increases in steatohepatitis.<\/jats:p>","DOI":"10.1152\/ajprenal.00308.2025","type":"journal-article","created":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T08:51:16Z","timestamp":1776934276000},"page":"F702-F711","update-policy":"https:\/\/doi.org\/10.1152\/aps-crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Endogenous oxalate synthesis in mouse models of metabolic dysfunction-associated steatotic liver disease"],"prefix":"10.1152","volume":"330","author":[{"given":"Xingsheng","family":"Li","sequence":"first","affiliation":[{"name":"University of Alabama at Birmingham","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Owen P.","family":"Cunneely","sequence":"additional","affiliation":[{"name":"University of Alabama at Birmingham","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6621-6096","authenticated-orcid":false,"given":"Jeremy B.","family":"Foote","sequence":"additional","affiliation":[{"name":"University of Alabama at Birmingham","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zachary R.","family":"Burns","sequence":"additional","affiliation":[{"name":"University of Alabama at Birmingham","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7451-7481","authenticated-orcid":false,"given":"Sonia","family":"Fargue","sequence":"additional","affiliation":[{"name":"University of Alabama at Birmingham","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dean G.","family":"Assimos","sequence":"additional","affiliation":[{"name":"University of Alabama at Birmingham","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Knight","sequence":"additional","affiliation":[{"name":"University of Alabama at Birmingham","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3518-9563","authenticated-orcid":false,"given":"Kyle D.","family":"Wood","sequence":"additional","affiliation":[{"name":"University of Alabama at Birmingham","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"24","reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1186\/s12902-022-00980-1"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.15280\/jlm.2015.5.1.7"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000012092"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1097\/MEG.0000000000002555"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejro.2016.07.004"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.18383\/j.tom.2020.00020"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1089\/end.2020.0486"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2016.11.097"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1111\/j.1523-1755.2005.00599.x"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2012.03.052"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.2003.00917.x"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1016\/j.mayocp.2015.07.016"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.07610715"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1089\/end.2015.0676"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2017.10.046"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.2001.00488.x"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1007\/s00240-016-0868-7"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymthe.2018.05.016"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbadis.2019.04.017"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-013-2444-5"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2021.109526"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfad106"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1038\/s42255-024-01134-4"},{"key":"B24","first-page":"67","volume":"7","author":"Jones AS","year":"2009","journal-title":"Int J Body Compos Res"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbadis.2015.12.001"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0607218103"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1152\/ajprenal.00473.2011"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1177\/12.5.333"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1002\/hep.20701"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1002\/hep.24127"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.1007\/s10735-025-10449-9"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-023-37908-9"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/7347068"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.1999.01377.x"},{"key":"B35","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.0000000000000176"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbadis.2016.02.004"},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbadis.2015.09.016"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.4254\/wjh.v11.i8.619"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.1016\/j.acthis.2022.151937"},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.1186\/s12876-020-01356-2"},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2017040390"},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.1016\/j.ab.2011.10.041"},{"key":"B43","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/819202"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrestox.1c00221"},{"key":"B45","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2021.595371"},{"key":"B46","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2019.12.025"},{"key":"B47","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2018.7614"},{"key":"B48","doi-asserted-by":"publisher","DOI":"10.3390\/antiox10020174"},{"key":"B49","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.16855"},{"key":"B50","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0271651"},{"key":"B51","doi-asserted-by":"publisher","DOI":"10.2337\/db15-0982"},{"key":"B52","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.00266.2018"},{"key":"B53","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms9050957"},{"key":"B54","doi-asserted-by":"publisher","DOI":"10.1002\/oby.20811"}],"container-title":["American Journal of Physiology-Renal Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.physiology.org\/doi\/pdf\/10.1152\/ajprenal.00308.2025","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T18:20:13Z","timestamp":1778696413000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.physiology.org\/doi\/10.1152\/ajprenal.00308.2025"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,1]]},"references-count":54,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,6,1]]}},"alternative-id":["10.1152\/ajprenal.00308.2025"],"URL":"https:\/\/doi.org\/10.1152\/ajprenal.00308.2025","relation":{},"ISSN":["1931-857X","1522-1466"],"issn-type":[{"value":"1931-857X","type":"print"},{"value":"1522-1466","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,1]]},"assertion":[{"value":"2025-08-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-09-04","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-20","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-13","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}