{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T21:36:54Z","timestamp":1778276214643,"version":"3.51.4"},"reference-count":7,"publisher":"American Physiological Society","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American Journal of Physiology-Renal Physiology"],"published-print":{"date-parts":[[2004,11]]},"abstract":"<jats:p> This essay looks at the historical significance of five APS classic papers that are freely available online: <\/jats:p><jats:p> Wearn JT and Richards AN. Observations on the composition of glomerular urine, with particular reference to the problem of reabsorption in the renal tubules. Am J Physiol 71: 209\u2014227, 1924 ( http:\/\/ajplegacy.physiology.org\/cgi\/reprint\/71\/1\/209 ). <\/jats:p><jats:p> Richards AN and Walker AM. Methods of collecting fluid from known regions of the renal tubules of Amphibia and of perfusing the lumen of a single tubule. Am J Physiol 118: 111\u2014120, 1936 ( http:\/\/ajplegacy.physiology.org\/cgi\/reprint\/118\/1\/111 ). <\/jats:p><jats:p> Walker AM and Hudson CL. The reabsorption of glucose from the renal tubule in Amphibia and the action of phlorhizin upon it. Am J Physiol 118: 130\u2014143, 1936 ( http:\/\/ajplegacy.physiology.org\/cgi\/reprint\/118\/1\/130 ). <\/jats:p><jats:p> Walker AM and Oliver J. Methods for the collection of fluid from single glomeruli and tubules of the mammalian kidney. Am J Physiol 134: 562\u2014579, 1941 ( http:\/\/ajplegacy.physiology.org\/cgi\/reprint\/134\/3\/562 ). <\/jats:p><jats:p> Walker AM, Bott PA, Oliver J, and MacDowell MC. The collection and analysis of fluid from single nephrons of the mammalian kidney. Am J Physiol 134: 580\u2014595, 1941 ( http:\/\/ajplegacy.physiology.org\/cgi\/reprint\/134\/3\/580 ). <\/jats:p>","DOI":"10.1152\/classicessays.00019.2004","type":"journal-article","created":{"date-parts":[[2004,10,8]],"date-time":"2004-10-08T22:52:57Z","timestamp":1097275977000},"page":"F866-F867","source":"Crossref","is-referenced-by-count":8,"title":["Micropuncture: unlocking the secrets of renal function"],"prefix":"10.1152","volume":"287","author":[{"given":"Jeff M.","family":"Sands","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"24","reference":[{"key":"R1","doi-asserted-by":"crossref","unstructured":"Burg M, Grantham J, Abramow M, and Orloff J. Preparation and study of fragments of single rabbit nephrons. Am J Physiol 210: 1293\u20131298, 1966.","DOI":"10.1152\/ajplegacy.1966.210.6.1293"},{"key":"R2","unstructured":"Gottschalk CW. A history of renal physiology to 1950. In: The Kidney. Physiology and Pathophysiology, edited by Seldin DW and Giebisch G. New York: Raven, 1992, p. 1\u201329."},{"key":"R3","doi-asserted-by":"crossref","unstructured":"Richards AN and Walker AM. Methods of collecting fluid from known regions of the renal tubules of Amphibia and of perfusing the lumen of a single tubule. Am J Physiol 118: 111\u2013120, 1936.","DOI":"10.1152\/ajplegacy.1936.118.1.111"},{"key":"R4","doi-asserted-by":"crossref","unstructured":"Walker AM, Bott PA, Oliver J, and MacDowell MC. The collection and analysis of fluid from single nephrons of the mammalian kidney. Am J Physiol 134: 580\u2013595, 1941.","DOI":"10.1152\/ajplegacy.1941.134.3.580"},{"key":"R5","doi-asserted-by":"crossref","unstructured":"Walker AM and Hudson CL. The reabsorption of glucose from the renal tubule in Amphibia and the action of phlorhizin upon it. Am J Physiol 118: 130\u2013143, 1936.","DOI":"10.1152\/ajplegacy.1936.118.1.130"},{"key":"R6","doi-asserted-by":"crossref","unstructured":"Walker AM and Oliver J. Methods for the collection of fluid from single glomeruli and tubules of the mammalian kidney. Am J Physiol 134: 562\u2013579, 1941.","DOI":"10.1152\/ajplegacy.1941.134.3.562"},{"key":"R7","doi-asserted-by":"crossref","unstructured":"Wearn JT and Richards AN. Observations on the composition of glomerular urine, with particular reference to the problem of reabsorption in the renal tubules. Am J Physiol 71: 209\u2013227, 1924.","DOI":"10.1152\/ajplegacy.1924.71.1.209"}],"container-title":["American Journal of Physiology-Renal Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.physiology.org\/doi\/pdf\/10.1152\/classicessays.00019.2004","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,8]],"date-time":"2019-09-08T17:52:42Z","timestamp":1567965162000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.physiology.org\/doi\/10.1152\/classicessays.00019.2004"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,11]]},"references-count":7,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2004,11]]}},"alternative-id":["10.1152\/classicessays.00019.2004"],"URL":"https:\/\/doi.org\/10.1152\/classicessays.00019.2004","relation":{},"ISSN":["1931-857X","1522-1466"],"issn-type":[{"value":"1931-857X","type":"print"},{"value":"1522-1466","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,11]]}}}