{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T06:15:42Z","timestamp":1772172942355,"version":"3.50.1"},"reference-count":0,"publisher":"American Physiological Society","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Applied Physiology"],"published-print":{"date-parts":[[1963,5,1]]},"abstract":"<jats:p> A trial is described in which 19 fit volunteers and 49 patients with malignant tumors have breathed oxygen at a pressure of 3\u20134 atm abs for periods of from 21 to 67 min in a pressure chamber filled with oxygen. Subjects at complete rest will not safely tolerate 4 atm abs for frac12 hr but are unlikely to show signs of oxygen toxicity in a similar period at 3 atm abs. One patient convulsed during decompression after 46frac14 min at 3 atm pressure. A slow, even rate of pressurization did not prevent the occurrence of otitic barotrauma in nine of the volunteers. The patients had myringotomies performed. Temperature and pulse rate changes are described. <\/jats:p><jats:p> Submitted on May 31, 1962 <\/jats:p>","DOI":"10.1152\/jappl.1963.18.3.492","type":"journal-article","created":{"date-parts":[[2017,12,24]],"date-time":"2017-12-24T17:47:54Z","timestamp":1514137674000},"page":"492-496","source":"Crossref","is-referenced-by-count":10,"title":["Response to high pressure oxygen of conscious volunteers and patients"],"prefix":"10.1152","volume":"18","author":[{"given":"C. A.","family":"Foster","sequence":"first","affiliation":[{"name":"Departments of Anaesthetics and Radiotherapy, St. Thomas' Hospital, London, England"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I.","family":"Churchill-Davidson","sequence":"additional","affiliation":[{"name":"Departments of Anaesthetics and Radiotherapy, St. Thomas' Hospital, London, England"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"24","container-title":["Journal of Applied Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.physiology.org\/doi\/pdf\/10.1152\/jappl.1963.18.3.492","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,8]],"date-time":"2019-09-08T23:03:41Z","timestamp":1567983821000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.physiology.org\/doi\/10.1152\/jappl.1963.18.3.492"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1963,5,1]]},"references-count":0,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1963,5,1]]}},"alternative-id":["10.1152\/jappl.1963.18.3.492"],"URL":"https:\/\/doi.org\/10.1152\/jappl.1963.18.3.492","relation":{},"ISSN":["8750-7587","1522-1601"],"issn-type":[{"value":"8750-7587","type":"print"},{"value":"1522-1601","type":"electronic"}],"subject":[],"published":{"date-parts":[[1963,5,1]]}}}