{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T21:41:10Z","timestamp":1778708470799,"version":"3.51.4"},"reference-count":0,"publisher":"American Physiological Society","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Applied Physiology"],"published-print":{"date-parts":[[1980,5,1]]},"abstract":"<jats:p> The mechanisms involved in producing intestinal vasoconstriction during a hyperthermia-producing intestinal vasoconstriction during a hyperthermia-producing environmental heat stress are unknown. Five conscious baboons (Papio anubis), each with chronically implanted catheters and a flow probe around the superior mesenteric artery, were subjected to environmental heating (Ta 40-45 degrees C) to raise their arterial blood temperature (Tbl) 2.0-2.6 degrees C to approximately 39.5 degrees C. Accompanying the gradual rise in Tbl was a fall in mean superior mesenteric artery blood flow (MSMF) and a progressive rise in superior mesenteric vascular resistance (SMR). At peak Tbl, MSMF had fallen 28.8 \u00b1 0.6% (mean \u00b1SE) and SMR had risen 50.2 \u00b1 4.2%. To determine the involvement of the sympathetic nervous system in producing this intestinal vasoconstriction, the baboon was subjected to environmental heating after induction of alpha-adrenergic receptor blockade by phenoxybenzamine or phentolamine. In this state, the rise in Tbl was accompanied by no change in MSMF and a slight, but not statistically significant, rise (7.8 \u00b1 3.8%) in SMR. Since alpha-receptor blockade nearly completely abolishes intestinal vasoconstriction during heat stress, this intestinal vasoconstriction must be mediated primarily by elevated sympathetic outflow. <\/jats:p>","DOI":"10.1152\/jappl.1980.48.5.759","type":"journal-article","created":{"date-parts":[[2017,12,25]],"date-time":"2017-12-25T06:36:19Z","timestamp":1514183779000},"page":"759-764","source":"Crossref","is-referenced-by-count":28,"title":["alpha-Adrenergic control of intestinal circulation in heat-stressed baboons"],"prefix":"10.1152","volume":"48","author":[{"given":"D. W.","family":"Proppe","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"24","container-title":["Journal of Applied Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.physiology.org\/doi\/pdf\/10.1152\/jappl.1980.48.5.759","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,9]],"date-time":"2019-09-09T06:04:19Z","timestamp":1568009059000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.physiology.org\/doi\/10.1152\/jappl.1980.48.5.759"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1980,5,1]]},"references-count":0,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1980,5,1]]}},"alternative-id":["10.1152\/jappl.1980.48.5.759"],"URL":"https:\/\/doi.org\/10.1152\/jappl.1980.48.5.759","relation":{},"ISSN":["8750-7587","1522-1601"],"issn-type":[{"value":"8750-7587","type":"print"},{"value":"1522-1601","type":"electronic"}],"subject":[],"published":{"date-parts":[[1980,5,1]]}}}