{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T14:52:56Z","timestamp":1758811976762},"reference-count":0,"publisher":"American Physiological Society","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Applied Physiology"],"published-print":{"date-parts":[[1982,4,1]]},"abstract":"<jats:p> Transpulmonary mechanics of anesthetized intubated dogs were studied during control breathing and hemorrhage-induced hyperventilation by least-mean-squares parameter estimation using several model versions. The classical elastance-resistance model was modified to include nonlinear elastic and viscous pressure terms with and without a linear inertive pressure component. Inclusion of the nonlinear terms decreased the root-mean-square error of fitting (q) of the classical model on the average to 67% in the control period and to 58% during hyperventilation. An additional decrease due to inertance was 4% (control) and 22% (hyperventilation) and was associated with acceptable estimates of inertance [0.056 +\/- 0.02 (SD) and 0.063 +\/- 0.008 cmH2O . l'1 . s2, respectively]. When inertance alone was added to the classical model, negligible improvement in q and unrealistic values of inertance were obtained. Conventional measures (Edyn and midvolume resistance) were close to the corresponding least-mean-squares estimates (E and R) of all model versions, except that in hyperventilation neglecting the inertance caused Edyn to markedly overestimate E of nonlinear inertive model. <\/jats:p>","DOI":"10.1152\/jappl.1982.52.4.955","type":"journal-article","created":{"date-parts":[[2017,12,24]],"date-time":"2017-12-24T23:46:56Z","timestamp":1514159216000},"page":"955-963","source":"Crossref","is-referenced-by-count":15,"title":["Parameter estimation of transpulmonary mechanics by a nonlinear inertive model"],"prefix":"10.1152","volume":"52","author":[{"given":"Z.","family":"Hantos","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Daroczy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Klebniczki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Dombos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Nagy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"24","container-title":["Journal of Applied Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.physiology.org\/doi\/pdf\/10.1152\/jappl.1982.52.4.955","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,9]],"date-time":"2019-09-09T00:35:48Z","timestamp":1567989348000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.physiology.org\/doi\/10.1152\/jappl.1982.52.4.955"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1982,4,1]]},"references-count":0,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1982,4,1]]}},"alternative-id":["10.1152\/jappl.1982.52.4.955"],"URL":"https:\/\/doi.org\/10.1152\/jappl.1982.52.4.955","relation":{},"ISSN":["8750-7587","1522-1601"],"issn-type":[{"value":"8750-7587","type":"print"},{"value":"1522-1601","type":"electronic"}],"subject":[],"published":{"date-parts":[[1982,4,1]]}}}