{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T22:57:14Z","timestamp":1771628234068,"version":"3.50.1"},"reference-count":0,"publisher":"American Physiological Society","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Applied Physiology"],"published-print":{"date-parts":[[1983,1,1]]},"abstract":"<jats:p> The purpose of this study was to determine if training in a cool (23 degrees C) environment would alter the potential for mortality or for tissue damage (as indicated by serum transaminase concentrations) during a work-heat tolerance test (WHTT) to exhaustion. Twenty-nine male Sprague-Dawley rats were trained (T) on a motorized treadmill for 6 wk, while 34 control animals of similar weight remained sedentary (S). Tissue damage among survivors 24 h following the WHTT and percent mortality were the same in both groups; however, T survivors 1) continued the test 44% longer (P less than 0.05), 2) performed significantly more work (P less than 0.05), and 3) sustained a 120% larger (P less than 0.05) thermal load [product of time and colonic temperature (Tc) above 40 degrees C] than S survivors. Mortality first occurred at a range in Tc of 40.6\u201341.0 degrees C in the S group compared with a range of 41.6\u201342.0 degrees C in the T group. Thus endurance T rats can run longer in the heat, sustain greater thermal loads, and are less susceptible to work-induced thermal fatality than S rats. <\/jats:p>","DOI":"10.1152\/jappl.1983.54.1.249","type":"journal-article","created":{"date-parts":[[2017,12,25]],"date-time":"2017-12-25T05:20:41Z","timestamp":1514179241000},"page":"249-253","source":"Crossref","is-referenced-by-count":23,"title":["Work-heat tolerance in endurance-trained rats"],"prefix":"10.1152","volume":"54","author":[{"given":"J. M.","family":"Fruth","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. V.","family":"Gisolfi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"24","container-title":["Journal of Applied Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.physiology.org\/doi\/pdf\/10.1152\/jappl.1983.54.1.249","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,9]],"date-time":"2019-09-09T05:39:08Z","timestamp":1568007548000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.physiology.org\/doi\/10.1152\/jappl.1983.54.1.249"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1983,1,1]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1983,1,1]]}},"alternative-id":["10.1152\/jappl.1983.54.1.249"],"URL":"https:\/\/doi.org\/10.1152\/jappl.1983.54.1.249","relation":{},"ISSN":["8750-7587","1522-1601"],"issn-type":[{"value":"8750-7587","type":"print"},{"value":"1522-1601","type":"electronic"}],"subject":[],"published":{"date-parts":[[1983,1,1]]}}}