{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T14:06:01Z","timestamp":1792677961592,"version":"4.5.0"},"reference-count":0,"publisher":"American Physiological Society","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Applied Physiology"],"published-print":{"date-parts":[[1985,4,1]]},"abstract":"<jats:p> In a controlled study of 11 male volunteers the following changes (means +\/- SD) were observed in venous blood during (D) and 75 min after (A) a period of 20 min of voluntary hyperventilation in comparison with before (B) hyperventilation (P values referring to the difference between D and B) erythrocyte count 5.18 +\/- 0.17 X 10(6) (B), 5.70 +\/- 0.21 X 10(6) (D) (P less than 0.001), and 5.18 +\/- 0.16 X 10(6)\/microliter (A); hemoglobin 15.7 +\/- 0.6 (B), 17.2 +\/- 0.7 (D) (P less than 0.001), and 15.8 +\/- 0.6 g\/dl (A); centrifuged hematocrit 46.6 +\/- 1.0 (B), 50.4 +\/- 1.7 (D) (P less than 0.001), and 47.0 +\/- 1.8% (A). The platelets increased from 159 +\/- 30 X 10(3) (B) to 205 +\/- 40 X 10(3) (D) (P less than 0.001) and returned to 157 +\/- 26 X 10(3)\/microliter (A). The leukocytes (WBC) were 4,210 +\/- 630 (B), 6,220 +\/- 1,660 (D) (P less than 0.001), and 6,190 +\/- 1,870\/microliter (A) (P less than 0.002, as compared with B). The rise of WBC during hyperventilation was mainly due to a 83% increase of lymphocytes, whereas a 93% increase of neutrophil leukocytes accounted for the increased WBC 75 min posthyperventilation. The increase of the ratio of band forms to segmented neutrophils from 9 (B) to 19% (A) (P less than 0.01) indicates that band forms were released from the bone marrow. The results show that WBC and platelets can be mobilized by hyperventilation by as yet unidentified mechanisms. <\/jats:p>","DOI":"10.1152\/jappl.1985.58.4.1170","type":"journal-article","created":{"date-parts":[[2017,12,21]],"date-time":"2017-12-21T08:16:32Z","timestamp":1513844192000},"page":"1170-1175","source":"Crossref","is-referenced-by-count":7,"title":["Hyperventilation-induced changes of the blood picture"],"prefix":"10.1152","volume":"58","author":[{"given":"M.","family":"Staubli","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"U. P.","family":"Stauble","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"U.","family":"Waber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P. W.","family":"Straub","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"24","container-title":["Journal of Applied Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.physiology.org\/doi\/pdf\/10.1152\/jappl.1985.58.4.1170","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,8]],"date-time":"2019-09-08T11:21:16Z","timestamp":1567941676000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.physiology.org\/doi\/10.1152\/jappl.1985.58.4.1170"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1985,4,1]]},"references-count":0,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1985,4,1]]}},"alternative-id":["10.1152\/jappl.1985.58.4.1170"],"URL":"https:\/\/doi.org\/10.1152\/jappl.1985.58.4.1170","relation":{},"ISSN":["8750-7587","1522-1601"],"issn-type":[{"value":"8750-7587","type":"print"},{"value":"1522-1601","type":"electronic"}],"subject":[],"published":{"date-parts":[[1985,4,1]]}}}