{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T08:23:00Z","timestamp":1790497380984,"version":"4.1.0"},"reference-count":0,"publisher":"American Physiological Society","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Applied Physiology"],"published-print":{"date-parts":[[1992,5,1]]},"abstract":"<jats:p> This study examined the time course of glycogen accumulation in skeletal muscle depleted by concentric work and subsequently subjected to eccentric exercise. Eight men exercised to exhaustion on a cycle ergometer [70% of maximal O2 consumption (VO2max)] and were placed on a carbohydrate-restricted diet. Approximately 12 h later they exercised one leg to subjective failure by repeated eccentric action of the knee extensors against a resistance equal to 120% of their one-repetition maximum concentric knee extension force (ECC leg). The contralateral leg was not exercised and served as a control (CON leg). During the 72-h recovery period, subjects consumed 7 g carbohydrate.kg body wt-1.day-1. Moderate soreness was experienced in the ECC leg 24\u201372 h after eccentric exercise. Muscle biopsies from the vastus lateralis of the ECC and CON legs revealed similar glycogen levels immediately after eccentric exercise (40.2 +\/- 5.2 and 47.6 +\/- 6.4 mmol\/kg wet wt, respectively; P greater than 0.05). There was no difference in the glycogen content of ECC and CON legs after 6 h of recovery (77.7 +\/- 7.9 and 85.1 +\/- 4.9 mmol\/kg wet wt, respectively; P greater than 0.05), but 18 h later, the ECC leg contained 15% less glycogen than the CON leg (90.2 +\/- 8.2 vs. 105.8 +\/- 8.9 mmol\/kg wet wt; P less than 0.05). After 72 h of recovery, this difference had increased to 24% (115.8 +\/- 8.0 vs. 153.0 +\/- 12.2 mmol\/kg wet wt; P less than 0.05). These data confirm that glycogen accumulation is impaired in eccentrically exercised muscle.(ABSTRACT TRUNCATED AT 250 WORDS) <\/jats:p>","DOI":"10.1152\/jappl.1992.72.5.1999","type":"journal-article","created":{"date-parts":[[2017,12,22]],"date-time":"2017-12-22T06:18:30Z","timestamp":1513923510000},"page":"1999-2004","source":"Crossref","is-referenced-by-count":44,"title":["Time course of glycogen accumulation after eccentric exercise"],"prefix":"10.1152","volume":"72","author":[{"given":"J. J.","family":"Widrick","sequence":"first","affiliation":[{"name":"Human Performance Laboratory, Ball State University, Muncie, Indiana 47306."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. L.","family":"Costill","sequence":"additional","affiliation":[{"name":"Human Performance Laboratory, Ball State University, Muncie, Indiana 47306."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G. K.","family":"McConell","sequence":"additional","affiliation":[{"name":"Human Performance Laboratory, Ball State University, Muncie, Indiana 47306."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. E.","family":"Anderson","sequence":"additional","affiliation":[{"name":"Human Performance Laboratory, Ball State University, Muncie, Indiana 47306."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. R.","family":"Pearson","sequence":"additional","affiliation":[{"name":"Human Performance Laboratory, Ball State University, Muncie, Indiana 47306."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. J.","family":"Zachwieja","sequence":"additional","affiliation":[{"name":"Human Performance Laboratory, Ball State University, Muncie, Indiana 47306."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"24","container-title":["Journal of Applied Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.physiology.org\/doi\/pdf\/10.1152\/jappl.1992.72.5.1999","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,8]],"date-time":"2019-09-08T17:15:08Z","timestamp":1567962908000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.physiology.org\/doi\/10.1152\/jappl.1992.72.5.1999"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1992,5,1]]},"references-count":0,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1992,5,1]]}},"alternative-id":["10.1152\/jappl.1992.72.5.1999"],"URL":"https:\/\/doi.org\/10.1152\/jappl.1992.72.5.1999","relation":{},"ISSN":["8750-7587","1522-1601"],"issn-type":[{"value":"8750-7587","type":"print"},{"value":"1522-1601","type":"electronic"}],"subject":[],"published":{"date-parts":[[1992,5,1]]}}}