{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T14:28:21Z","timestamp":1776090501352,"version":"3.50.1"},"reference-count":0,"publisher":"American Physiological Society","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Applied Physiology"],"published-print":{"date-parts":[[1993,4,1]]},"abstract":"<jats:p> In 31 anesthetized rabbits, after removal of superficial tissues, glass micropipettes filled with 0.5 M NaCl solution and connected to an electrohydraulic servo-null system were used to measure extraperitoneal interstitial fluid pressure (Pi,per) and peritoneal liquid pressure (Pliq,per) at various heights. Linear regressions relating pressure to recording height (H) were Pi,per = 1.07 \u2013 0.27H and Pliq,per = 0.9 \u2013 0.64H, respectively. Protein concentration (Cp;g\/dl) and colloid osmotic pressure (II; cmH2O) of plasma and of peritoneal and pleural liquids were 5.48 +\/- 0.38 and 24.61 +\/- 3.23, 3.07 +\/- 0.5 and 13.29 +\/- 1.87, and 1.76 +\/- 0.42 and 8.45 +\/- 2, respectively. The equation relating II to Cp was II = 4.64Cp + 0.0027Cp2. Tissue fluid samples were collected with saline-soaked wicks implanted in vivo or dry wicks inserted postmortem in extraperitoneal and extrapleural interstitial spaces. After 60 and 15 min, respectively, wicks were withdrawn and centrifuged; wick fluid was analyzed in colloid osmometer for small samples. Average extraperitoneal and extrapleural II values were 14.2 +\/- 2.49 and 11.94 +\/- 1.52 cmH2O, corresponding to Cp of 3.07 and 2.57 g\/dl, respectively. The average net pressure gradient, assuming reflection coefficient and hydraulic conductivity (Negrini et al. J. Appl. Physiol. 69: 625\u2013630, 1990; 71: 2543\u20132547, 1991), was 1.18 and 0.98 cmH2O for parietal peritoneal and pleural mesothelia, respectively, favoring filtration from the extraserosal interstitia into the serosal cavities. Total parietal peritoneal filtration was 1.49 ml.kg-1.h-1, approximately 15-fold higher than that for pleural mesothelium. <\/jats:p>","DOI":"10.1152\/jappl.1993.74.4.1779","type":"journal-article","created":{"date-parts":[[2017,12,21]],"date-time":"2017-12-21T18:46:02Z","timestamp":1513881962000},"page":"1779-1784","source":"Crossref","is-referenced-by-count":25,"title":["Fluid exchanges across the parietal peritoneal and pleural mesothelia"],"prefix":"10.1152","volume":"74","author":[{"given":"D.","family":"Negrini","sequence":"first","affiliation":[{"name":"Istituto di Fisiologia Umana, Universita degli Studi, Milan, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"del Fabbro","sequence":"additional","affiliation":[{"name":"Istituto di Fisiologia Umana, Universita degli Studi, Milan, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Venturoli","sequence":"additional","affiliation":[{"name":"Istituto di Fisiologia Umana, Universita degli Studi, Milan, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"24","container-title":["Journal of Applied Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.physiology.org\/doi\/pdf\/10.1152\/jappl.1993.74.4.1779","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,8]],"date-time":"2019-09-08T12:28:21Z","timestamp":1567945701000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.physiology.org\/doi\/10.1152\/jappl.1993.74.4.1779"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1993,4,1]]},"references-count":0,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1993,4,1]]}},"alternative-id":["10.1152\/jappl.1993.74.4.1779"],"URL":"https:\/\/doi.org\/10.1152\/jappl.1993.74.4.1779","relation":{},"ISSN":["8750-7587","1522-1601"],"issn-type":[{"value":"8750-7587","type":"print"},{"value":"1522-1601","type":"electronic"}],"subject":[],"published":{"date-parts":[[1993,4,1]]}}}