{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T10:57:26Z","timestamp":1769165846100,"version":"3.49.0"},"reference-count":13,"publisher":"American Physiological Society","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Applied Physiology"],"published-print":{"date-parts":[[1996,10,1]]},"abstract":"<jats:p>Carvalho, Paula, Jacob Hildebrandt, and Nirmal B. Charan.Changes in bronchial and pulmonary arterial blood flow with progressive tension pneumothorax. J. Appl. Physiol. 81(4): 1664\u20131669, 1996.\u2014We studied the effects of unilateral tension pneumothorax and its release on bronchial and pulmonary arterial blood flow and gas exchange in 10 adult anesthetized and mechanically ventilated sheep with chronically implanted ultrasonic flow probes. Right pleural pressure (Ppl) was increased in two steps from \u22125 to 10 and 25 cmH<jats:sub>2<\/jats:sub>O and then decreased to 10 and \u22125 cmH<jats:sub>2<\/jats:sub>O. Each level of Ppl was maintained for 5 min. Bronchial blood flow, right and left pulmonary arterial flows, cardiac output (Q\u02d9t), hemodynamic measurements, and arterial blood gases were obtained at the end of each period. Pneumothorax resulted in a 66% decrease inQ\u02d9t, bronchial blood flow decreased by 84%, and right pulmonary arterial flow decreased by 80% at Ppl of 25 cmH<jats:sub>2<\/jats:sub>O ( P &lt; 0.001). At peak Ppl, the majority ofQ\u02d9t was due to blood flow through the left pulmonary artery. With resolution of pneumothorax, hemodynamic parameters normalized, although abnormalities in gas exchange persisted for 60\u201390 min after recovery and were associated with a decrease in total respiratory compliance.<\/jats:p>","DOI":"10.1152\/jappl.1996.81.4.1664","type":"journal-article","created":{"date-parts":[[2017,12,22]],"date-time":"2017-12-22T07:23:31Z","timestamp":1513927411000},"page":"1664-1669","source":"Crossref","is-referenced-by-count":15,"title":["Changes in bronchial and pulmonary arterial blood flow with progressive tension pneumothorax"],"prefix":"10.1152","volume":"81","author":[{"given":"Paula","family":"Carvalho","sequence":"first","affiliation":[{"name":"Pulmonary Research Laboratory, Department of Veterans Affairs Medical Center, Boise, Idaho 83702; and Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Washington, Seattle, Washington 98195"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacob","family":"Hildebrandt","sequence":"additional","affiliation":[{"name":"Pulmonary Research Laboratory, Department of Veterans Affairs Medical Center, Boise, Idaho 83702; and Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Washington, Seattle, Washington 98195"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nirmal B.","family":"Charan","sequence":"additional","affiliation":[{"name":"Pulmonary Research Laboratory, Department of Veterans Affairs Medical Center, Boise, Idaho 83702; and Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Washington, Seattle, Washington 98195"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"24","reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1984.56.5.1289"},{"key":"B2","doi-asserted-by":"crossref","first-page":"280","DOI":"10.2460\/ajvr.1989.50.02.280","volume":"50","author":"Bennett R. 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