{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T14:14:10Z","timestamp":1773756850206,"version":"3.50.1"},"reference-count":26,"publisher":"American Physiological Society","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Applied Physiology"],"published-print":{"date-parts":[[1997,8,1]]},"abstract":"<jats:p> Beaumont, Maurice, Damien Lejeune, Henri Marotte, Alain Harf, and Fr\u00e9d\u00e9ric Lofaso. Effects of chest wall counterpressures on lung mechanics under high levels of CPAP in humans. J. Appl. Physiol. 83(2): 591\u2013598, 1997.\u2014We assessed the respective effects of thoracic (TCP) and abdominal\/lower limb (ACP) counterpressures on end-expiratory volume (EEV) and respiratory muscle activity in humans breathing at 40 cmH<jats:sub>2<\/jats:sub>O of continuous positive airway pressure (CPAP). Expiratory activity was evaluated on the basis of the inspiratory drop in gastric pressure (\u0394Pga) from its maximal end-expiratory level, whereas inspiratory activity was evaluated on the basis of the transdiaphragmatic pressure-time product (PTPdi). CPAP induced hyperventilation (+320%) and only a 28% increase in EEV because of a high level of expiratory activity (\u0394Pga = 24 \u00b1 5 cmH<jats:sub>2<\/jats:sub>O), contrasting with a reduction in PTPdi from 17 \u00b1 2 to 9 \u00b1 7 cmH<jats:sub>2<\/jats:sub>O \u22c5 s<jats:sup>\u22121<\/jats:sup> \u22c5 cycle<jats:sup>\u22121<\/jats:sup>during 0 and 40 cmH<jats:sub>2<\/jats:sub>O of CPAP, respectively. When ACP, TCP, or both were added, hyperventilation decreased and PTPdi increased (19 \u00b1 5, 21 \u00b1 5, and 35 \u00b1 7 cmH<jats:sub>2<\/jats:sub>O \u22c5 s<jats:sup>\u22121<\/jats:sup> \u22c5 cycle<jats:sup>\u22121<\/jats:sup>, respectively), whereas \u0394Pga decreased (19 \u00b1 6, 9 \u00b1 4, and 2 \u00b1 2 cmH<jats:sub>2<\/jats:sub>O, respectively). We concluded that during high-level CPAP, TCP and ACP limit lung hyperinflation and expiratory muscle activity and restore diaphragmatic activity. <\/jats:p>","DOI":"10.1152\/jappl.1997.83.2.591","type":"journal-article","created":{"date-parts":[[2017,12,22]],"date-time":"2017-12-22T18:39:11Z","timestamp":1513967951000},"page":"591-598","source":"Crossref","is-referenced-by-count":7,"title":["Effects of chest wall counterpressures on lung mechanics  under high levels of CPAP in humans"],"prefix":"10.1152","volume":"83","author":[{"given":"Maurice","family":"Beaumont","sequence":"first","affiliation":[{"name":"Laboratoire de M\u00e9decine A\u00e9rospatiale, Centre d\u2019Essais en Vol, F-91228 Br\u00e9tigny-sur-Orge C\u00e9dex, and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Damien","family":"Lejeune","sequence":"additional","affiliation":[{"name":"Laboratoire de M\u00e9decine A\u00e9rospatiale, Centre d\u2019Essais en Vol, F-91228 Br\u00e9tigny-sur-Orge C\u00e9dex, and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henri","family":"Marotte","sequence":"additional","affiliation":[{"name":"Laboratoire de M\u00e9decine A\u00e9rospatiale, Centre d\u2019Essais en Vol, F-91228 Br\u00e9tigny-sur-Orge C\u00e9dex, and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alain","family":"Harf","sequence":"additional","affiliation":[{"name":"Service de Physiologie-Explorations fonctionnelles and Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale U296, H\u00f4pital H. Mondor, F-94010 Cr\u00e9teil, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fr\u00e9d\u00e9ric","family":"Lofaso","sequence":"additional","affiliation":[{"name":"Service de Physiologie-Explorations fonctionnelles and Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale U296, H\u00f4pital H. Mondor, F-94010 Cr\u00e9teil, France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"24","reference":[{"key":"B1","first-page":"753","volume":"49","author":"Ackles K. N.","year":"1978","journal-title":"Aviat. Space Environ. Med."},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1962.17.2.215"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1987.62.5.2026"},{"key":"B5","first-page":"599","volume":"49","author":"Balldin U. I.","year":"1978","journal-title":"Aviat. Space Environ. Med."},{"key":"B6","first-page":"851","volume":"51","author":"Balldin U. I.","year":"1980","journal-title":"Aviat. Space Environ. 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