{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T11:01:37Z","timestamp":1793271697516,"version":"4.5.0"},"reference-count":29,"publisher":"American Physiological Society","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Applied Physiology"],"published-print":{"date-parts":[[1997,10,1]]},"abstract":"<jats:p> Franklin, Karl A., Erik Sandstr\u00f6m, G\u00f6ran Johansson, and Eva M. B\u00e5lfors. Hemodynamics, cerebral circulation, and oxygen saturation in Cheyne-Stokes respiration. J. Appl. Physiol. 83(4): 1184\u20131191, 1997.\u2014Because cardiovascular disorders and stroke may induce Cheyne-Stokes respiration, our purpose was to study the interaction among cerebral activity, cerebral circulation, blood pressure, and blood gases during Cheyne-Stokes respiration. Ten patients with heart failure or a previous stroke were investigated during Cheyne-Stokes respiration with recordings of daytime polysomnography, cerebral blood flow velocity, intra-arterial blood pressure, and intra-arterial oxygen saturation with and without oxygen administration. There were simultaneous changes in wakefulness, cerebral blood flow velocity, and respiration with accompanying changes in blood pressure and heart rate \u223c10 s later. Cerebral blood flow velocity, blood pressure, and heart rate had a minimum occurrence in apnea and a maximum occurrence during hyperpnea. The apnea-induced oxygen desaturations were diminished during oxygen administration, but the hemodynamic alterations persisted. Oxygen desaturations were more severe and occurred earlier according to intra-arterial measurements than with finger oximetry. It is not possible to explain Cheyne-Stokes respiration by alterations in blood gases and circulatory time alone. Cheyne-Stokes respiration may be characterized as a state of phase-linked cyclic changes in cerebral, respiratory, and cardiovascular functions probably generated by variations in central nervous activity. <\/jats:p>","DOI":"10.1152\/jappl.1997.83.4.1184","type":"journal-article","created":{"date-parts":[[2017,12,22]],"date-time":"2017-12-22T18:35:16Z","timestamp":1513967716000},"page":"1184-1191","source":"Crossref","is-referenced-by-count":78,"title":["Hemodynamics, cerebral circulation, and oxygen saturation  in Cheyne-Stokes respiration"],"prefix":"10.1152","volume":"83","author":[{"given":"Karl A.","family":"Franklin","sequence":"first","affiliation":[{"name":"Departments of Pulmonary Medicine,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erik","family":"Sandstr\u00f6m","sequence":"additional","affiliation":[{"name":"Thoracic Surgery, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G\u00f6ran","family":"Johansson","sequence":"additional","affiliation":[{"name":"Anesthesia and Critical Care Medicine, University Hospital, S-901 85 Ume\u00e5, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva M.","family":"B\u00e5lfors","sequence":"additional","affiliation":[{"name":"Anesthesia and Critical Care Medicine, University Hospital, S-901 85 Ume\u00e5, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"24","reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1982.57.6.0769"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(96)00024-1"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1172\/JCI100480"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.150.6.7952619"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.17.5.913"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/15.2.173"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(02)21857-7"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(61)90173-5"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1988.64.3.1000"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197305032881810"},{"key":"B11","first-page":"216","volume":"2","author":"Cheyne J.","year":"1818","journal-title":"Dublin Hosp. 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