{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T15:34:52Z","timestamp":1791300892895,"version":"4.1.0"},"reference-count":21,"publisher":"American Physiological Society","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Applied Physiology"],"published-print":{"date-parts":[[1998,6,1]]},"abstract":"<jats:p> Our laboratory has shown previously that a low level of dynamic exercise induced by electrical stimulation of the mesencephalic locomotor region (MLR) stimulated group III and IV muscle afferents in decerebrate unanesthetized cats (C. M. Adreani, J. M. Hill, and M. P. Kaufman. J. Appl. Physiol. 83: 1811\u20131817, 1997). In the present study, we have extended these findings by examining the effect of occluding the arterial supply to the dynamically exercising muscles on the afferents\u2019 responses to MLR stimulation. In decerebrate cats, we found that arterial occlusion increased the responsiveness to a low level of dynamic exercise in 44% of the group III and 47% of the group IV afferents tested. Occlusion, compared with the freely perfused state, did not increase the concentrations of either hydrogen ion or lactate ion in the venous effluent from the exercising muscles. We conclude that arterial occlusion caused some unspecified substance to accumulate in the working muscles to increase the sensitivity of equal percentages of group III and IV afferents to dynamic exercise. <\/jats:p>","DOI":"10.1152\/jappl.1998.84.6.1827","type":"journal-article","created":{"date-parts":[[2017,12,22]],"date-time":"2017-12-22T15:09:52Z","timestamp":1513955392000},"page":"1827-1833","source":"Crossref","is-referenced-by-count":112,"title":["Effect of arterial occlusion on responses of group III  and IV afferents to dynamic exercise"],"prefix":"10.1152","volume":"84","author":[{"given":"Christine M.","family":"Adreani","sequence":"first","affiliation":[{"name":"Division of Cardiovascular Medicine, Departments of Internal Medicine and Human Physiology, University of California, Davis, California 95616"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc P.","family":"Kaufman","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Medicine, Departments of Internal Medicine and Human Physiology, University of California, Davis, California 95616"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"24","reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1997.82.6.1811"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1937.sp003485"},{"issue":"13","key":"B3","first-page":"H546","volume":"244","author":"Bockman E. 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