{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,14]],"date-time":"2026-03-14T03:12:48Z","timestamp":1773457968195,"version":"3.50.1"},"reference-count":29,"publisher":"American Physiological Society","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Applied Physiology"],"published-print":{"date-parts":[[1998,7,1]]},"abstract":"<jats:p>The etiology of exercise hypocapnia is unknown. The contributions of exercise intensity (ExInt), lactic acid, environmental temperature, rectal temperature (T<jats:sub>re<\/jats:sub>), and physical conditioning to the variance in arterial CO<jats:sub>2<\/jats:sub>tension ([Formula: see text]) in the exercising sheep were quantified. We hypothesized that thermal drive contributes to hyperventilation. Four unshorn sheep were exercised at \u223c30, 50, and 70% of maximal O<jats:sub>2<\/jats:sub>consumption for 30 min, or until exhaustion, both before and after 5 wk of physical conditioning. In addition, two of the sheep were shorn and exercised at each intensity in a cold (&lt;15\u00b0C) environment. T<jats:sub>re<\/jats:sub>and O<jats:sub>2<\/jats:sub>consumption were measured continuously. Lactic acid and [Formula: see text] were measured at 5- to 10-min intervals. Data were analyzed by multiple regression on[Formula: see text]. During exercise, T<jats:sub>re<\/jats:sub>rose and[Formula: see text] fell, except at the lowest ExInt in the cold environment. T<jats:sub>re<\/jats:sub>explained 77% of the variance in [Formula: see text], and ExInt explained 5%. All other variables were insignificant. We conclude that, in sheep, thermal drive contributes to hyperventilation during exercise.<\/jats:p>","DOI":"10.1152\/jappl.1998.85.1.318","type":"journal-article","created":{"date-parts":[[2017,12,22]],"date-time":"2017-12-22T20:06:46Z","timestamp":1513973206000},"page":"318-325","source":"Crossref","is-referenced-by-count":21,"title":["Thermal drive contributes to hyperventilation during exercise in sheep"],"prefix":"10.1152","volume":"85","author":[{"given":"Pauline L.","family":"Entin","sequence":"first","affiliation":[{"name":"Department of Physiology, Cornell University, Ithaca, New York 14853"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Robertshaw","sequence":"additional","affiliation":[{"name":"Department of Physiology, Cornell University, Ithaca, New York 14853"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard E.","family":"Rawson","sequence":"additional","affiliation":[{"name":"Department of Physiology, Cornell University, Ithaca, New York 14853"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"24","reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.ph.44.030182.000505"},{"key":"B2","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1111\/j.2042-3306.1995.tb04884.x","volume":"18","author":"Bayly W.","year":"1995","journal-title":"Equine Vet. 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