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The severities of hind leg splaying and wobbling were quantifiable, whereas nose down and belly dragging were expressed in all-or-none fashion. Interrater reliabilities were substantial (0.75 \u2264 r \u2264 0.99). Splay scores (rated 0\u20135) displayed significant effects of strain, dose, and time point. Wobbling (rated 0\u20134) was dependent on strain and time point. Ethanol affected wobbling (most strains scored &gt;0 at some time), but all doses were equally effective. Incidence of nose down and belly dragging behaviors increased strain dependently after ethanol, but strains did not differentially respond to dose. Ethanol-induced splaying was modestly, and negatively, genetically correlated with wobbling. Nose down and belly dragging tended to be associated with splaying and wobbling at later times. Four distinct ataxia-related behaviors were sensitive to ethanol. Strains differed in ethanol sensitivity for all measures. Modest strain mean correlations among behaviors indicate that these behaviors are probably under control of largely different genes and that ataxia rating scales should rate separate behaviors on discrete scales. <\/jats:p>","DOI":"10.1152\/japplphysiol.00086.2004","type":"journal-article","created":{"date-parts":[[2004,3,23]],"date-time":"2004-03-23T01:53:39Z","timestamp":1080006819000},"page":"360-368","source":"Crossref","is-referenced-by-count":31,"title":["Observer-rated ataxia: rating scales for assessment of genetic differences in ethanol-induced intoxication in mice"],"prefix":"10.1152","volume":"97","author":[{"given":"Pamela","family":"Metten","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karyn L.","family":"Best","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andy J.","family":"Cameron","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alisha B.","family":"Saultz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jessica M.","family":"Zuraw","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chia-Hua","family":"Yu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Douglas","family":"Wahlsten","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John C.","family":"Crabbe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"24","reference":[{"key":"R1","doi-asserted-by":"publisher","DOI":"10.1016\/S0920-1211(98)00085-0"},{"key":"R2","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)80086-0"},{"key":"R3","doi-asserted-by":"publisher","DOI":"10.1037\/0735-7044.114.2.401"},{"key":"R4","unstructured":"Bogo V, Hill TA, and Young RW. 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