{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,19]],"date-time":"2025-11-19T11:34:48Z","timestamp":1763552088562,"version":"3.40.5"},"reference-count":57,"publisher":"American Physiological Society","issue":"1","content-domain":{"domain":["journals.physiology.org"],"crossmark-restriction":true},"short-container-title":["Journal of Applied Physiology"],"published-print":{"date-parts":[[2021,1,1]]},"abstract":"<jats:p> NEW &amp; NOTEWORTHY: We provide novel data demonstrating that the presence of muscle pain interferes with estimations of torque produced by the knee extensors, which could impair judgment of work rate during endurance exercise. The novelty of our study is in the application of the hypertonic saline experimental model into a quadriceps muscle during short, submaximal isometric contractions at an intensity that provides a more translatable assessment of the impact of exercise-induced pain on work-rate regulation during whole body exercise. <\/jats:p>","DOI":"10.1152\/japplphysiol.00139.2020","type":"journal-article","created":{"date-parts":[[2020,11,5]],"date-time":"2020-11-05T20:21:18Z","timestamp":1604607678000},"page":"57-68","update-policy":"https:\/\/doi.org\/10.1152\/aps-crossmark-policy","source":"Crossref","is-referenced-by-count":11,"title":["Muscle pain from an intramuscular injection of hypertonic saline increases variability in knee extensor torque reproduction"],"prefix":"10.1152","volume":"130","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0833-0878","authenticated-orcid":false,"given":"Samuel A.","family":"Smith","sequence":"first","affiliation":[{"name":"Endurance Research Group, School of Sport and Exercise Sciences, University of Kent, Chatham Maritime, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dominic","family":"Micklewright","sequence":"additional","affiliation":[{"name":"School of Sport, Rehabilitation and Exercise Sciences, University of Essex, Wivenhoe Park, Colchester, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samantha L.","family":"Winter","sequence":"additional","affiliation":[{"name":"Endurance Research Group, School of Sport and Exercise Sciences, University of Kent, Chatham Maritime, United Kingdom"},{"name":"School of Sport, Exercise and Health Sciences, Loughborough University, Ashby Road, Loughborough, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6685-5800","authenticated-orcid":false,"given":"Alexis R.","family":"Mauger","sequence":"additional","affiliation":[{"name":"Endurance Research Group, School of Sport and Exercise Sciences, University of Kent, Chatham Maritime, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"24","reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.3109\/00207459809003340"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2001.013385"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.2147\/OAJSM.S38599"},{"key":"B4","first-page":"119","volume":"27","author":"O\u2019Connor PJ","year":"1999","journal-title":"Exerc Sport Sci Rev"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1113\/expphysiol.2013.075812"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2015.284380"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1007\/s40279-013-0091-4"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1136\/bjsm.2008.050799"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2010.10.020"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00761.2009"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2008.163303"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2011.213769"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1016\/S0924-980X(96)96554-6"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1007\/s00421-020-04425-2"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1016\/j.humov.2004.08.012"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440-1681.2003.03880.x"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1080\/0899022031000083816"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1007\/s00221-011-2991-6"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.3109\/08990220.2010.483204"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.3758\/BF03193146"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1037\/0022-3514.54.6.1063"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1249\/00005768-198025000-00008"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1097\/00005768-199708000-00004"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1007\/s00421-016-3532-6"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3959(75)90044-5"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00280.2014"},{"volume-title":"Human Kinetics","year":"1998","author":"Borg GA","key":"B27"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1016\/j.gaitpost.2013.11.020"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1037\/0033-2909.125.3.356"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.2001.81.4.1725"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.1017\/S0140525X0007254X"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1002\/(sici)1097-4598(199911)22:11<1564::aid-mus12>3.0.co;2-3"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1016\/S1388-2457(01)00631-9"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainresbull.2011.11.003"},{"key":"B35","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.88.6.2297"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.2000.278.6.H2039"},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.1037\/0096-1523.25.3.837"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.1249\/MSS.0000000000001445"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-0102(99)00006-1"},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.1007\/s00421-012-2343-7"},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.1016\/S0966-6362(01)00157-6"},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00048.2011"},{"key":"B43","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2004.03.005"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.1139\/y91-102"},{"key":"B45","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejpain.2010.03.006"},{"key":"B46","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2008.10.029"},{"key":"B47","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.5211-08.2009"},{"key":"B48","doi-asserted-by":"publisher","DOI":"10.1080\/17461391.2019.1599450"},{"key":"B49","doi-asserted-by":"publisher","DOI":"10.1113\/EP087295"},{"key":"B50","doi-asserted-by":"publisher","DOI":"10.1007\/s00421-014-3036-1"},{"key":"B51","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2013.04.011"},{"key":"B52","doi-asserted-by":"publisher","DOI":"10.1152\/jn.2000.84.4.1708"},{"key":"B53","doi-asserted-by":"publisher","DOI":"10.2522\/ptj.20100330"},{"key":"B54","doi-asserted-by":"publisher","DOI":"10.1016\/j.orthres.2004.06.008"},{"key":"B55","doi-asserted-by":"publisher","DOI":"10.1053\/eujp.2002.0332"},{"key":"B56","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2011.11.026"},{"key":"B57","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00920.2005"}],"container-title":["Journal of Applied Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.physiology.org\/doi\/pdf\/10.1152\/japplphysiol.00139.2020","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,6,23]],"date-time":"2021-06-23T09:57:46Z","timestamp":1624442266000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.physiology.org\/doi\/10.1152\/japplphysiol.00139.2020"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1,1]]},"references-count":57,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,1,1]]}},"alternative-id":["10.1152\/japplphysiol.00139.2020"],"URL":"https:\/\/doi.org\/10.1152\/japplphysiol.00139.2020","relation":{},"ISSN":["8750-7587","1522-1601"],"issn-type":[{"type":"print","value":"8750-7587"},{"type":"electronic","value":"1522-1601"}],"subject":[],"published":{"date-parts":[[2021,1,1]]},"assertion":[{"value":"2020-02-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-10-30","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-01-14","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}