{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T19:25:40Z","timestamp":1790623540245,"version":"4.1.0"},"reference-count":72,"publisher":"American Physiological Society","issue":"3","funder":[{"DOI":"10.13039\/100006133","name":"DOE | Advanced Research Projects Agency - Energy (ARPA-E)","doi-asserted-by":"publisher","award":["DE-AR0000529"],"award-info":[{"award-number":["DE-AR0000529"]}],"id":[{"id":"10.13039\/100006133","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006133","name":"DOE | Advanced Research Projects Agency - Energy (ARPA-E)","doi-asserted-by":"publisher","award":["DE-AR0000529"],"award-info":[{"award-number":["DE-AR0000529"]}],"id":[{"id":"10.13039\/100006133","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Applied Physiology"],"published-print":{"date-parts":[[2018,9,1]]},"abstract":"<jats:p> The ability of hands and feet to convey skin thermal sensations is an important contributor to our experience of the surrounding world. Surprisingly, the detailed topographical distribution of warm and cold thermosensitivity across hands and feet has not been mapped, although sensitivity maps exist for touch and pain. Using a recently developed quantitative sensory test, we mapped warm and cold thermosensitivity of 103 skin sites over glabrous and hairy skin of hands and feet in male (M; 30.2\u2009\u00b1\u20095.8 yr) and female (F; 27.7\u2009\u00b1\u20095.1 yr) adults matched for body surface area (M: 1.77\u2009\u00b1\u20090.2 m<jats:sup>2<\/jats:sup>; F: 1.64\u2009\u00b1\u20090.1 m<jats:sup>2<\/jats:sup>; P = 0.155). Findings indicated that warm and cold thermosensitivity varies by fivefold across glabrous and hairy skin of hands and feet and that hands (warm\/cold sensitivity: 1.25\/2.14 vote\/\u00b0C) are twice as sensitive as the feet (warm\/cold sensitivity: 0.51\/0.99 vote\/\u00b0C). Opposite to what is known for touch and pain sensitivity, we observed a characteristic distal-to-proximal increase in thermosensitivity over both hairy and glabrous skin (i.e., from fingers and toes to body of hands and feet), and found that hairy skin is more sensitive than glabrous. Finally, we show that body surface area-matched men and women presented small differences in thermosensitivity and that these differences are constrained to glabrous skin only. Our high-density thermosensory micromapping provides the most detailed thermosensitivity maps of hands and feet in young adults available to date. These maps offer a window into peripheral and central mechanisms of thermosensory integration in humans and will help guide future developments in smart skin and sensory neuroprostheses, in wearable, energy-efficient personal comfort systems, and in sport and protective clothing. <\/jats:p><jats:p> NEW &amp; NOTEWORTHY We provide the most detailed thermosensitivity maps across glabrous and hairy skin of hands and feet in men and women available to date. Our maps show that thermosensitivity varies by fivefold across hands and feet, distal regions (e.g., fingers, toes) are less sensitive than proximal (e.g., palm, sole), hands are twice as sensitive as feet, and men and women present small thermosensitivity differences. These findings will help guide developments in sensory neuroprostheses, wearable comfort systems, and sport\/protective clothing. <\/jats:p>","DOI":"10.1152\/japplphysiol.00158.2018","type":"journal-article","created":{"date-parts":[[2018,6,7]],"date-time":"2018-06-07T12:23:10Z","timestamp":1528374190000},"page":"723-736","source":"Crossref","is-referenced-by-count":91,"title":["Thermosensory micromapping of warm and cold sensitivity across glabrous and hairy skin of male and female hands and feet"],"prefix":"10.1152","volume":"125","author":[{"given":"Davide","family":"Filingeri","sequence":"first","affiliation":[{"name":"THERMOSENSELAB, Environmental Ergonomics Research Centre, Loughborough University, Loughborough, United Kingdom"},{"name":"Center for the Built Environment, University of California at Berkeley, Berkeley, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Zhang","sequence":"additional","affiliation":[{"name":"Center for the 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