{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T17:53:34Z","timestamp":1782150814164,"version":"3.54.5"},"reference-count":49,"publisher":"American Physiological Society","issue":"6","funder":[{"DOI":"10.13039\/501100003407","name":"Ministero dell'Istruzione, dell'Universit\u00e0 e della Ricerca","doi-asserted-by":"publisher","award":["2020477RW5"],"award-info":[{"award-number":["2020477RW5"]}],"id":[{"id":"10.13039\/501100003407","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003407","name":"Ministero dell'Istruzione, dell'Universit\u00e0 e della Ricerca","doi-asserted-by":"publisher","award":["P2022FNCPR"],"award-info":[{"award-number":["P2022FNCPR"]}],"id":[{"id":"10.13039\/501100003407","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"HHS | NIH | National Institute on Aging","doi-asserted-by":"publisher","award":["AG048262"],"award-info":[{"award-number":["AG048262"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.physiology.org"],"crossmark-restriction":true},"short-container-title":["Journal of Applied Physiology"],"published-print":{"date-parts":[[2026,6,1]]},"abstract":"<jats:p>\n                    We report in vivo neuromuscular function, single-fiber mechanics, and denervation markers in a 91-yr-old female who holds the W90\n                    <jats:sup>+<\/jats:sup>\n                    200 m world record. Despite reduced muscle size, force, and power, as well as pronounced fast-fiber atrophy, markers of denervation were similar to those in young females and single-fiber force in slow fibers was preserved. Together, these data highlight the differential effects of lifelong sprint training and aging on neural versus muscular components of the neuromuscular system.\n                  <\/jats:p>","DOI":"10.1152\/japplphysiol.00280.2026","type":"journal-article","created":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T16:01:52Z","timestamp":1778083312000},"page":"1605-1613","update-policy":"https:\/\/doi.org\/10.1152\/aps-crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["The other half of the sprinting coin: the neuromuscular profile of a 91-yr-old female world record sprinter"],"prefix":"10.1152","volume":"140","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6181-492X","authenticated-orcid":false,"given":"Marta","family":"Colosio","sequence":"first","affiliation":[{"name":"University of Pavia","place":["Italy"]},{"name":"University of Wisconsin\u2013Madison","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabell","family":"Dobrzycki","sequence":"additional","affiliation":[{"name":"University of Wisconsin\u2013Madison","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura E.","family":"Teigen","sequence":"additional","affiliation":[{"name":"University of Wisconsin\u2013Madison","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0877-7960","authenticated-orcid":false,"given":"Marco","family":"Carbonaro","sequence":"additional","affiliation":[{"name":"Politecnico di Torino","place":["Italy"]},{"name":"University of Twente","place":["The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Massimiliano","family":"Ansaldo","sequence":"additional","affiliation":[{"name":"University of Pavia","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6370-7925","authenticated-orcid":false,"given":"Marco","family":"Gatti","sequence":"additional","affiliation":[{"name":"University of Pavia","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2013-1652","authenticated-orcid":false,"given":"Clarissa Muller","family":"Brusco","sequence":"additional","affiliation":[{"name":"University of Padova","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monica","family":"Canepari","sequence":"additional","affiliation":[{"name":"University of Pavia","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4960-7490","authenticated-orcid":false,"given":"Roberto","family":"Bottinelli","sequence":"additional","affiliation":[{"name":"University of Pavia","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Botter","sequence":"additional","affiliation":[{"name":"Politecnico di Torino","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9494-0858","authenticated-orcid":false,"given":"Simone","family":"Porcelli","sequence":"additional","affiliation":[{"name":"University of Pavia","place":["Italy"]},{"name":"Fondazione IRCCS Policlinico San Matteo","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3165-4536","authenticated-orcid":false,"given":"Martino V.","family":"Franchi","sequence":"additional","affiliation":[{"name":"University of Padova","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6709-4078","authenticated-orcid":false,"given":"Christopher W.","family":"Sundberg","sequence":"additional","affiliation":[{"name":"University of Wisconsin\u2013Madison","place":["United States"]},{"name":"University of Wisconsin\u2013Madison","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"24","reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00299.2006"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00475.2016"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.14283\/jfa.2020.19"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.01141.2017"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00319.2022"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.2165\/11590560-000000000-00000"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.2165\/11590550-000000000-00000"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1016\/j.cophys.2019.05.004"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00921.2002"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1097\/JES.0b013e318258e1c1"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00279.2026"},{"key":"B12","doi-asserted-by":"publisher","unstructured":"Carbonaro M, Boccardo M, Brusco CM, Pilotto AM, Re R, Lauretani F, Porcelli S, Franchi MV, Botter A. Motor unit behaviour adaptations across the lifespan: sex differences in young, middle-aged and old adults (Preprint). bioRxiv 2025. doi:10.64898\/2025.12.19.695460.","DOI":"10.64898\/2025.12.19.695460"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1249\/MSS.0000000000000929"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1046\/j.1532-5415.2002.50216.x"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/61.10.1059"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1093\/bmb\/ldq008"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1016\/j.exger.2013.02.012"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1113\/JP282298"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.00575.2019"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.00445.2025"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1113\/EP092222"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.70005"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2020.00946"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1159\/000524843"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1002\/jcsm.12720"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1249\/MSS.0000000000003015"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1249\/MSS.0000000000002123"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1109\/TNSRE.2022.3140220"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1088\/1741-2560\/13\/2\/026027"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1016\/j.jelekin.2020.102426"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00159.2026"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1113\/JP276018"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.00206.2014"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.1016\/0076-6879(88)57093-3"},{"key":"B35","first-page":"463","volume":"75","author":"Fabiato A","year":"1979","journal-title":"J Physiol (Paris)"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.1002\/jcsm.13531"},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.1002\/mus.26638"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.1007\/s11357-013-9517-z"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.1002\/JCSM.12477"},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.1016\/j.arr.2018.07.005"},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.1016\/j.exger.2016.12.021"},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/glaa013"},{"key":"B43","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00773.2023"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.1113\/JP280679"},{"key":"B45","doi-asserted-by":"publisher","DOI":"10.1002\/mus.20392"},{"key":"B46","doi-asserted-by":"publisher","DOI":"10.1111\/apha.13803"},{"key":"B47","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00459.2019"},{"key":"B48","doi-asserted-by":"publisher","DOI":"10.1113\/JP270561"},{"key":"B49","doi-asserted-by":"publisher","DOI":"10.1113\/JP278261"}],"container-title":["Journal of Applied Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.physiology.org\/doi\/pdf\/10.1152\/japplphysiol.00280.2026","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T17:40:30Z","timestamp":1782150030000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.physiology.org\/doi\/10.1152\/japplphysiol.00280.2026"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,1]]},"references-count":49,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,6,1]]}},"alternative-id":["10.1152\/japplphysiol.00280.2026"],"URL":"https:\/\/doi.org\/10.1152\/japplphysiol.00280.2026","relation":{},"ISSN":["8750-7587","1522-1601"],"issn-type":[{"value":"8750-7587","type":"print"},{"value":"1522-1601","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,1]]},"assertion":[{"value":"2026-03-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-03","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-29","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-27","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}