{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,5]],"date-time":"2026-07-05T02:09:01Z","timestamp":1783217341727,"version":"3.54.6"},"reference-count":29,"publisher":"American Physiological Society","issue":"4","funder":[{"DOI":"10.13039\/100000897","name":"Cystic Fibrosis Foundation","doi-asserted-by":"publisher","award":["MCNALL19K0"],"award-info":[{"award-number":["MCNALL19K0"]}],"id":[{"id":"10.13039\/100000897","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100023551","name":"Cystic Fibrosis Ireland","doi-asserted-by":"publisher","award":["RECOVER01"],"award-info":[{"award-number":["RECOVER01"]}],"id":[{"id":"10.13039\/501100023551","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000292","name":"Cystic Fibrosis Trust","doi-asserted-by":"publisher","award":["VIA083"],"award-info":[{"award-number":["VIA083"]}],"id":[{"id":"10.13039\/501100000292","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000850","name":"National Heart and Lung Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000850","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.physiology.org"],"crossmark-restriction":true},"short-container-title":["Journal of Applied Physiology"],"published-print":{"date-parts":[[2024,10,1]]},"abstract":"<jats:p> We consider the term \u201ctrapped air\u201d either in the use of imaging or pulmonary function testing, something of a misnomer that can lead to an inaccurate assessment of an important physiological feature. Instead, we propose the term underventilated lung units (UVLU). Of the many pulmonary function methods we used in this study, we found that the use of multiple breath washout with short extension (MBW<jats:sub>ShX<\/jats:sub>) to be the best nonimaging method. <\/jats:p>","DOI":"10.1152\/japplphysiol.00340.2024","type":"journal-article","created":{"date-parts":[[2024,8,8]],"date-time":"2024-08-08T19:48:55Z","timestamp":1723146535000},"page":"883-891","update-policy":"https:\/\/doi.org\/10.1152\/aps-crossmark-policy","source":"Crossref","is-referenced-by-count":6,"title":["Silence of the lungs: comparing measures of slow and noncommunicating lung units from pulmonary function tests with computed tomography"],"prefix":"10.1152","volume":"137","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3131-7639","authenticated-orcid":false,"given":"Christopher","family":"Short","sequence":"first","affiliation":[{"name":"National Heart and Lung Institute, Imperial College London, London, United Kingdom"},{"name":"Royal Brompton and Harefield Hospitals, Guys and St Thomas\u2019 Trust, London, United Kingdom"},{"name":"European Cystic Fibrosis Society, Lung Clearance Index Core Facility, London, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Semple","sequence":"additional","affiliation":[{"name":"National Heart and Lung Institute, Imperial College London, London, United Kingdom"},{"name":"Royal Brompton and Harefield Hospitals, Guys and St Thomas\u2019 Trust, London, United Kingdom"},{"name":"Paediatrics and Child Health, Imperial College London, London, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary","family":"Abkir","sequence":"additional","affiliation":[{"name":"National Heart and Lung Institute, Imperial College London, London, United Kingdom"},{"name":"Royal Brompton and Harefield Hospitals, Guys and St Thomas\u2019 Trust, London, United Kingdom"},{"name":"European Cystic Fibrosis Society, Lung Clearance Index Core Facility, London, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon","family":"Padley","sequence":"additional","affiliation":[{"name":"National Heart and Lung Institute, Imperial College London, London, United Kingdom"},{"name":"Royal Brompton and Harefield Hospitals, Guys and St Thomas\u2019 Trust, London, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Rosenthal","sequence":"additional","affiliation":[{"name":"National Heart and Lung Institute, Imperial College London, London, United Kingdom"},{"name":"Royal Brompton and Harefield Hospitals, Guys and St Thomas\u2019 Trust, London, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"McNally","sequence":"additional","affiliation":[{"name":"RCSI University of Medicine and Health Sciences, Dublin, Ireland"},{"name":"Children\u2019s Health Ireland, Dublin, Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harm","family":"Tiddens","sequence":"additional","affiliation":[{"name":"Department of Paediatric Pulmonology and Allergology, Erasmus MC\u2014Sophia Children\u2019s Hospital, Rotterdam, The Netherlands"},{"name":"Department of Radiology and Nuclear Medicine, Erasmus MC, Rotterdam, The Netherlands"},{"name":"Thirona, Nijmegen, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daan","family":"Caudri","sequence":"additional","affiliation":[{"name":"Department of Paediatric Pulmonology and Allergology, Erasmus MC\u2014Sophia Children\u2019s Hospital, Rotterdam, The Netherlands"},{"name":"Department of Radiology and Nuclear Medicine, Erasmus MC, Rotterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Bush","sequence":"additional","affiliation":[{"name":"National Heart and Lung Institute, Imperial College London, London, United Kingdom"},{"name":"Royal Brompton and Harefield Hospitals, Guys and St Thomas\u2019 Trust, London, United Kingdom"},{"name":"Paediatrics and Child Health, Imperial College London, London, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jane C.","family":"Davies","sequence":"additional","affiliation":[{"name":"National Heart and Lung Institute, Imperial College London, London, United Kingdom"},{"name":"Royal Brompton and Harefield Hospitals, Guys and St Thomas\u2019 Trust, London, United Kingdom"},{"name":"European Cystic Fibrosis Society, Lung Clearance Index Core Facility, London, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"24","reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.157.5.rsaa-2"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.1971.51.2.368"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.20879"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcf.2020.07.023"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcf.2013.09.005"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcf.2020.10.007"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1159\/000193921"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1159\/000194281"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.1950170410"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.10221"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.10310"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcf.2021.06.013"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201908-1590ST"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00080312"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.00289-2020"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00069712"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcf.2019.11.006"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201501-0061OC"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.3390\/medicina57050503"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.24646"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197801052980103"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1002\/ppul.24931"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2020191429"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1513\/AnnalsATS.201606-448FR"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcf.2013.05.012"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1976.40.5.819"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.27030"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.25992"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1016\/S1569-1993(23)00294-1"}],"container-title":["Journal of Applied Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.physiology.org\/doi\/pdf\/10.1152\/japplphysiol.00340.2024","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,24]],"date-time":"2024-09-24T02:14:34Z","timestamp":1727144074000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.physiology.org\/doi\/10.1152\/japplphysiol.00340.2024"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,1]]},"references-count":29,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,10,1]]}},"alternative-id":["10.1152\/japplphysiol.00340.2024"],"URL":"https:\/\/doi.org\/10.1152\/japplphysiol.00340.2024","relation":{},"ISSN":["8750-7587","1522-1601"],"issn-type":[{"value":"8750-7587","type":"print"},{"value":"1522-1601","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10,1]]},"assertion":[{"value":"2024-05-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-07-24","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-08-06","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-09-23","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}