{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T10:52:51Z","timestamp":1773312771208,"version":"3.50.1"},"reference-count":80,"publisher":"American Physiological Society","issue":"5","funder":[{"DOI":"10.13039\/100000002","name":"HHS | National Institutes of Health","doi-asserted-by":"publisher","award":["R01 HL096787"],"award-info":[{"award-number":["R01 HL096787"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"HHS | National Institutes of Health","doi-asserted-by":"publisher","award":["R01 HL161233"],"award-info":[{"award-number":["R01 HL161233"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.physiology.org"],"crossmark-restriction":true},"short-container-title":["Journal of Applied Physiology"],"published-print":{"date-parts":[[2024,5,1]]},"abstract":"<jats:p> The mechanisms of decreased incidence of cardiovascular disease (CVD) in reproductive-age women compared with age-matched men are unknown. The strong association between elevated sympathetic activity and CVD led us to characterize splanchnic sympathetic bursts in female and male rats. Prepubescent males and females exhibited narrower sympathetic bursts, whereas young adult males had higher resting burst frequency compared with age-matched females. Sex-based regulation of sympathetic activity suggests a need for sex-dependent therapeutic strategies to combat CVD. <\/jats:p>","DOI":"10.1152\/japplphysiol.00649.2023","type":"journal-article","created":{"date-parts":[[2024,3,21]],"date-time":"2024-03-21T08:01:45Z","timestamp":1711008105000},"page":"1170-1181","update-policy":"https:\/\/doi.org\/10.1152\/aps-crossmark-policy","source":"Crossref","is-referenced-by-count":4,"title":["Influence of sex and sedentary conditions on sympathetic burst characteristics in prepubertal, postpubertal, and young adult rats"],"prefix":"10.1152","volume":"136","author":[{"given":"Shivansh A.","family":"Desai","sequence":"first","affiliation":[{"name":"Department of Physiology, Wayne State University School of Medicine, Detroit, Michigan, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Umme Aiman","family":"Mirza","sequence":"additional","affiliation":[{"name":"Department of Physiology, Wayne State University School of Medicine, Detroit, Michigan, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7720-1519","authenticated-orcid":false,"given":"Patrick J.","family":"Mueller","sequence":"additional","affiliation":[{"name":"Department of Physiology, Wayne State University School of Medicine, Detroit, Michigan, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"24","reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1161\/hc4601.099487"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2017-015857"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2010.02.112"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1016\/j.annepidem.2009.01.019"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1016\/j.pcad.2014.08.002"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.4082\/kjfm.2017.38.3.111"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1007\/s12471-010-0841-y"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1161\/01.hyp.37.4.1053"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjhyper.2007.06.007"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1186\/2042-6410-3-7"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.117.07802"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2009-0997"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1136\/pgmj.2006.048371"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.0000160318.46725.46"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.4070\/kcj.2018.0448"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1038\/nrn1902"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1093\/acprof:oso\/9780195306637.003.0005"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1097\/00004872-200110000-00002"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.1994.74.2.323"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1972.32.2.213"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.108.119990"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00078.2013"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2009.186387"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2010.200691"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.109.145110"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.107.090696"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.1993.265.2.R365"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2016.00290"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00961.2011"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00537.2013"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.1113\/JP281757"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.1986.251.4.R700"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1097\/00004872-199917060-00001"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00703.2016"},{"key":"B35","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00397.2021"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.1007\/s11906-011-0196-9"},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00841.2017"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.1016\/s0301-0082(98)00030-6"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00004.2020"},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.120.15208"},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.1996.271.6.H2563"},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.1016\/0165-1838(92)90200-z"},{"key":"B43","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1681.1997.tb02693.x"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00366.2016"},{"key":"B45","doi-asserted-by":"publisher","DOI":"10.1210\/endo-109-6-2032"},{"key":"B46","doi-asserted-by":"publisher","DOI":"10.1177\/0192623308315665"},{"key":"B47","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00191.2009"},{"key":"B48","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.1992.263.4.H1311"},{"key":"B49","doi-asserted-by":"publisher","DOI":"10.1016\/0165-1838(93)90125-e"},{"key":"B50","doi-asserted-by":"publisher","DOI":"10.1161\/01.hyp.21.4.498"},{"key":"B51","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00026.2019"},{"key":"B52","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.111.181131"},{"key":"B53","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.116.07792"},{"key":"B54","doi-asserted-by":"publisher","DOI":"10.1113\/EP085472"},{"key":"B55","doi-asserted-by":"publisher","DOI":"10.1113\/expphysiol.2008.046300"},{"key":"B56","doi-asserted-by":"publisher","DOI":"10.1016\/j.autneu.2015.08.004"},{"key":"B57","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.0000055190.81716.ab"},{"key":"B58","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.0000052949.85257.8E"},{"key":"B59","doi-asserted-by":"publisher","DOI":"10.1385\/ENDO:25:1:15"},{"key":"B60","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00820.2004"},{"key":"B61","doi-asserted-by":"publisher","DOI":"10.1016\/j.autneu.2014.02.005"},{"key":"B62","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00813.2004"},{"key":"B63","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00474.2004"},{"key":"B64","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.1989.257.5.E654"},{"key":"B65","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.106.085548"},{"key":"B66","doi-asserted-by":"publisher","DOI":"10.1111\/sms.14300"},{"key":"B67","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.1998.275.5.R1600"},{"key":"B68","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00450.2022"},{"key":"B69","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2003-030722"},{"key":"B70","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2011.212753"},{"key":"B71","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2011.224642"},{"key":"B72","doi-asserted-by":"publisher","DOI":"10.1113\/JP272167"},{"key":"B73","doi-asserted-by":"publisher","DOI":"10.1007\/s10286-020-00722-0"},{"key":"B74","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.1998.275.6.R1909"},{"key":"B75","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.1998.274.4.H1194"},{"key":"B76","doi-asserted-by":"publisher","DOI":"10.1016\/s1566-0702(02)00132-7"},{"key":"B77","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00544.2001"},{"key":"B78","doi-asserted-by":"publisher","DOI":"10.1007\/s11906-011-0188-9"},{"key":"B79","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.101.8.862"},{"key":"B80","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.01197.2008"}],"container-title":["Journal of Applied Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.physiology.org\/doi\/pdf\/10.1152\/japplphysiol.00649.2023","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,8]],"date-time":"2024-05-08T02:38:34Z","timestamp":1715135914000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.physiology.org\/doi\/10.1152\/japplphysiol.00649.2023"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5,1]]},"references-count":80,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2024,5,1]]}},"alternative-id":["10.1152\/japplphysiol.00649.2023"],"URL":"https:\/\/doi.org\/10.1152\/japplphysiol.00649.2023","relation":{},"ISSN":["8750-7587","1522-1601"],"issn-type":[{"value":"8750-7587","type":"print"},{"value":"1522-1601","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,5,1]]},"assertion":[{"value":"2023-09-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-03-07","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-03-15","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-05-07","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}