{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T02:50:39Z","timestamp":1788922239555,"version":"build-2803163510"},"reference-count":71,"publisher":"American Physiological Society","issue":"1","funder":[{"DOI":"10.13039\/100000090","name":"DOD | MHS | Congressionally Directed Medical Research Programs","doi-asserted-by":"publisher","award":["Applied Pain Research Program"],"award-info":[{"award-number":["Applied Pain Research Program"]}],"id":[{"id":"10.13039\/100000090","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100013132","name":"Combat Casualty Care Research Program","doi-asserted-by":"publisher","award":["D_007_2017_USAISR"],"award-info":[{"award-number":["D_007_2017_USAISR"]}],"id":[{"id":"10.13039\/100013132","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Clinical and Rehabilitative Medicine Research Program"}],"content-domain":{"domain":["journals.physiology.org"],"crossmark-restriction":true},"short-container-title":["Journal of Applied Physiology"],"published-print":{"date-parts":[[2025,7,1]]},"abstract":"<jats:p> Administration of an analgesic dose of either morphine, fentanyl, or sufentanil produced only modest and transient effects on cardiorespiratory function after either moderate (37% blood volume) or severe (50%) hemorrhage in conscious rats with extremity trauma. Under the conditions of these experiments, analgesic doses of these commonly used opioids also did not alter survival after traumatic hemorrhage. <\/jats:p>","DOI":"10.1152\/japplphysiol.00708.2024","type":"journal-article","created":{"date-parts":[[2025,3,17]],"date-time":"2025-03-17T13:01:26Z","timestamp":1742216486000},"page":"145-161","update-policy":"https:\/\/doi.org\/10.1152\/aps-crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["Effects of analgesic doses of opioids on cardiorespiratory responses and survival to hemorrhage and trauma in rats"],"prefix":"10.1152","volume":"139","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-3544-0942","authenticated-orcid":false,"given":"Stephanie M.","family":"Marshall-Lipiec","sequence":"first","affiliation":[{"name":"US Army Institute of Surgical Research","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathy L.","family":"Ryan","sequence":"additional","affiliation":[{"name":"US Army Institute of Surgical Research","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariam L.","family":"Calderon","sequence":"additional","affiliation":[{"name":"US Army Institute of Surgical Research","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cassandra M.","family":"Rodriguez","sequence":"additional","affiliation":[{"name":"US Army Institute of Surgical Research","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian S.","family":"Connor","sequence":"additional","affiliation":[{"name":"US Army Institute of Surgical Research","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7104-3305","authenticated-orcid":false,"given":"Carmen","family":"Hinojosa-Laborde","sequence":"additional","affiliation":[{"name":"US Army Institute of Surgical Research","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9499-0599","authenticated-orcid":false,"given":"Harold G.","family":"Klemcke","sequence":"additional","affiliation":[{"name":"US Army Institute of Surgical Research","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"24","reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.17226\/23511"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.3109\/10903127.2013.844873"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.7205\/MILMED-D-14-00383"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1093\/milmed\/usac211"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.55460\/8CBI-GAOD"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1016\/j.wem.2023.09.003"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00476.2020"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1944.62850170001007"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.7205\/milmed-d-10-00172"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1007\/s00204-021-03068-2"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1172\/JCI107869"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1007\/s11906-022-01205-5"},{"key":"B13","first-page":"48","volume":"18","author":"Zweifach BW","year":"1945","journal-title":"Surgery"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1152\/ajplegacy.1947.148.2.269"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1152\/ajplegacy.1949.157.2.259"},{"key":"B16","first-page":"567","volume":"55","author":"Chasnow EA","year":"1964","journal-title":"Surgery"},{"key":"B17","first-page":"293","volume":"19","author":"Feuerstein G","year":"1986","journal-title":"Circ Shock"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.1987.253.3.H507"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1111\/j.1472-8206.1998.tb00996.x"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1097\/01.shk.0000126904.67614.21"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1943.01220160010002"},{"key":"B22","first-page":"375","volume":"9","author":"Isoyama T","year":"1982","journal-title":"Circ Shock"},{"key":"B23","first-page":"219","volume":"27","author":"Feuerstein G","year":"1989","journal-title":"Circ Shock"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1016\/s0006-8993(97)00379-x"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1097\/00005373-199812000-00009"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1113\/eph8702432"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00191.2022"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1097\/TA.0000000000001833"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1080\/10903127.2019.1657213"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajem.2023.04.020"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.1080\/14656566.2020.1766025"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1016\/j.anclin.2010.08.010"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1345\/aph.1P438"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.1097\/TA.0000000000002604"},{"key":"B35","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0000000000004654"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.1097\/shk.0b013e31815cfe30"},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00837.2003"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.2134\/agronj2013.0148"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00528.2013"},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.1097\/TA.0000000000003711"},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1681.1995.tb01945.x"},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.1080\/10903120500373264"},{"key":"B43","doi-asserted-by":"publisher","DOI":"10.7205\/MILMED-D-14-00257"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-199907000-00024"},{"key":"B45","doi-asserted-by":"publisher","DOI":"10.1213\/00000539-199102000-00006"},{"key":"B46","doi-asserted-by":"publisher","DOI":"10.1213\/00000539-198303000-00003"},{"key":"B47","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.1991.260.2.H305"},{"key":"B48","doi-asserted-by":"publisher","DOI":"10.1016\/S1566-0702(03)00152-8"},{"key":"B49","doi-asserted-by":"publisher","DOI":"10.1016\/j.resp.2013.11.005"},{"key":"B50","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3565(25)25010-8"},{"key":"B51","doi-asserted-by":"publisher","DOI":"10.1124\/jpet.121.000675"},{"key":"B52","doi-asserted-by":"publisher","DOI":"10.1016\/j.jemermed.2005.02.007"},{"key":"B53","doi-asserted-by":"publisher","DOI":"10.3109\/10903120903572301"},{"key":"B54","doi-asserted-by":"publisher","DOI":"10.1016\/j.annemergmed.2010.03.020"},{"key":"B55","first-page":"239","volume":"23","author":"Brown JW","year":"2005","journal-title":"Shock"},{"key":"B56","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2005.01.069"},{"key":"B57","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.1998.275.3.E440"},{"key":"B58","doi-asserted-by":"publisher","DOI":"10.1007\/s12272-013-0072-z"},{"key":"B59","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-200007000-00047"},{"key":"B60","doi-asserted-by":"publisher","DOI":"10.4103\/2231-4040.191414"},{"key":"B61","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3565(25)31057-8"},{"key":"B62","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3565(24)37304-5"},{"key":"B63","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00640.2013"},{"key":"B64","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00006.2018"},{"key":"B65","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00217.2021"},{"key":"B66","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00003.2024"},{"key":"B67","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjao.2023.100204"},{"key":"B68","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00091.2022"},{"key":"B69","doi-asserted-by":"publisher","DOI":"10.1097\/TA.0000000000003252"},{"key":"B70","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-020-05428-y"},{"key":"B71","doi-asserted-by":"publisher","DOI":"10.1016\/j.injury.2016.10.037"}],"container-title":["Journal of Applied Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.physiology.org\/doi\/pdf\/10.1152\/japplphysiol.00708.2024","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,28]],"date-time":"2025-07-28T15:38:32Z","timestamp":1753717112000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.physiology.org\/doi\/10.1152\/japplphysiol.00708.2024"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,1]]},"references-count":71,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,7,1]]}},"alternative-id":["10.1152\/japplphysiol.00708.2024"],"URL":"https:\/\/doi.org\/10.1152\/japplphysiol.00708.2024","relation":{},"ISSN":["8750-7587","1522-1601"],"issn-type":[{"value":"8750-7587","type":"print"},{"value":"1522-1601","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,1]]},"assertion":[{"value":"2024-09-17","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-11-18","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-03-05","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-30","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}