{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T23:38:05Z","timestamp":1782949085355,"version":"3.54.5"},"reference-count":34,"publisher":"American Physiological Society","issue":"6","funder":[{"DOI":"10.13039\/100000050","name":"HHS | NIH | National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["R01HL-057354"],"award-info":[{"award-number":["R01HL-057354"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000968","name":"American Heart Association","doi-asserted-by":"publisher","award":["23CDA1051777"],"award-info":[{"award-number":["23CDA1051777"]}],"id":[{"id":"10.13039\/100000968","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"HHS | NIH | National Institute on Aging","doi-asserted-by":"publisher","award":["5P30AG028716-18"],"award-info":[{"award-number":["5P30AG028716-18"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.physiology.org"],"crossmark-restriction":true},"short-container-title":["Journal of Applied Physiology"],"published-print":{"date-parts":[[2025,6,1]]},"abstract":"<jats:p> This exploratory analysis investigated longitudinal effects of accumulating similar total exercise program volumes at different weekly exercise energy expenditures on cardiorespiratory fitness and metabolic syndrome measures over months to years. In general, adaptations are similar; however, factors other than total energy cost\u2014such as exercise frequency or duration\u2014may modulate longitudinal improvements in cardiorespiratory fitness and skeletal muscle insulin sensitivity over 33 mo of training among sedentary adults with overweight or obesity and dyslipidemia. <\/jats:p>","DOI":"10.1152\/japplphysiol.00743.2024","type":"journal-article","created":{"date-parts":[[2025,5,30]],"date-time":"2025-05-30T16:10:24Z","timestamp":1748621424000},"page":"1532-1542","update-policy":"https:\/\/doi.org\/10.1152\/aps-crossmark-policy","source":"Crossref","is-referenced-by-count":3,"title":["Cumulative effects of training at different weekly energy expenditures on cardiorespiratory fitness and markers of metabolic syndrome in STRRIDE-Extension"],"prefix":"10.1152","volume":"138","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6576-3469","authenticated-orcid":false,"given":"Garrett A.","family":"Moseley","sequence":"first","affiliation":[{"name":"Duke University School of Medicine","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1407-1622","authenticated-orcid":false,"given":"Leanna M.","family":"Ross","sequence":"additional","affiliation":[{"name":"Duke University School of Medicine Durham","place":["United States"]},{"name":"Duke University School of Medicine","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9712-8980","authenticated-orcid":false,"given":"Katherine A.","family":"Collins-Bennett","sequence":"additional","affiliation":[{"name":"Duke University School of Medicine Durham","place":["United States"]},{"name":"Duke University School of Medicine","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2877-3801","authenticated-orcid":false,"given":"Rebecca","family":"North","sequence":"additional","affiliation":[{"name":"Duke University School of Medicine","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9766-1814","authenticated-orcid":false,"given":"Johanna L.","family":"Johnson","sequence":"additional","affiliation":[{"name":"Duke University School of Medicine Durham","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1930-9684","authenticated-orcid":false,"given":"William E.","family":"Kraus","sequence":"additional","affiliation":[{"name":"Duke University School of Medicine Durham","place":["United States"]},{"name":"Duke University School of Medicine","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"24","reference":[{"key":"B1","volume-title":"2018 Physical Activity Guidelines Advisory Committee Scientific Report","author":"Committee PAGA","year":"2018"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1089\/jwh.2008.0790"},{"key":"B3","first-page":"881","volume":"4","author":"Alizadeh Z","year":"2013","journal-title":"Int J Prev Med"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1097\/00005768-199801000-00021"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1001\/jama.290.10.1323"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1001\/jama.297.19.2081"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa020194"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-publhealth-031210-101151"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1136\/bjsports-2018-100393"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.7326\/M14-1189"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1038\/oby.2007.178"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/78.4.684"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00071.2018"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1007\/s40279-019-01145-2"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.116.136408"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1123\/jpah.2013-0047"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1097\/01.hjr.0000198921.34814.4d"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1093\/her\/14.6.803"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1177\/146642400312400109"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1378\/chest.128.4.2788"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00707.2003"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00124.2005"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2007.07.027"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1097\/00005768-200110000-00025"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1161\/ATVBAHA.117.310307"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1080\/00913847.1985.11708790"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1210\/edrv-6-1-45"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.105.169404"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1001\/jama.273.5.402"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1186\/s12905-017-0421-z"},{"key":"B31","first-page":"893","volume":"19","author":"Jakicic JM","year":"1995","journal-title":"Int J Obes Relat Metab Disord"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.163.11.1343"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.3390\/nu7053677"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/nqz054"}],"container-title":["Journal of Applied Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.physiology.org\/doi\/pdf\/10.1152\/japplphysiol.00743.2024","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,16]],"date-time":"2025-06-16T18:16:24Z","timestamp":1750097784000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.physiology.org\/doi\/10.1152\/japplphysiol.00743.2024"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,1]]},"references-count":34,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,6,1]]}},"alternative-id":["10.1152\/japplphysiol.00743.2024"],"URL":"https:\/\/doi.org\/10.1152\/japplphysiol.00743.2024","relation":{},"ISSN":["8750-7587","1522-1601"],"issn-type":[{"value":"8750-7587","type":"print"},{"value":"1522-1601","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6,1]]},"assertion":[{"value":"2024-09-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-10-15","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-05-21","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-16","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}