{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T18:14:18Z","timestamp":1785435258875,"version":"3.56.0"},"reference-count":50,"publisher":"American Physiological Society","issue":"6","content-domain":{"domain":["journals.physiology.org"],"crossmark-restriction":true},"short-container-title":["Journal of Applied Physiology"],"published-print":{"date-parts":[[2025,6,1]]},"abstract":"<jats:p>\n                    This study presents an electrical model of the cardiovascular system, capable of estimating breath-by-breath intra-trunk blood shifting (Vbs\n                    <jats:sub>IT<\/jats:sub>\n                    ) between the abdomen and thorax. The model was validated using data from healthy participants performing various breathing patterns during exercise. It allowed quantifying Vbs\n                    <jats:sub>IT<\/jats:sub>\n                    fluctuations, with significant increases during abdominal and rib cage breathing and expiratory flow limitation. This model offers a valuable tool for exploring cardiorespiratory function in health and disease, including COPD and heart failure.\n                  <\/jats:p>","DOI":"10.1152\/japplphysiol.00749.2024","type":"journal-article","created":{"date-parts":[[2025,5,26]],"date-time":"2025-05-26T13:00:57Z","timestamp":1748264457000},"page":"1581-1599","update-policy":"https:\/\/doi.org\/10.1152\/aps-crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["A data-driven model to estimate breathing-induced intra-trunk blood shifts during exercise"],"prefix":"10.1152","volume":"138","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-3658-887X","authenticated-orcid":false,"given":"Gabriele","family":"Corigliano","sequence":"first","affiliation":[{"name":"Politecnico di Milano","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Uva","sequence":"additional","affiliation":[{"name":"University of Lausanne","place":["Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9776-7501","authenticated-orcid":false,"given":"Bengt","family":"Kayser","sequence":"additional","affiliation":[{"name":"University of Lausanne","place":["Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2950-0231","authenticated-orcid":false,"given":"Andrea","family":"Aliverti","sequence":"additional","affiliation":[{"name":"Politecnico di Milano","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5548-7755","authenticated-orcid":false,"given":"Fr\u00e9d\u00e9ric","family":"Stucky","sequence":"additional","affiliation":[{"name":"University of Lausanne","place":["Switzerland"]},{"id":[{"id":"https:\/\/ror.org\/01znkr924","id-type":"ROR","asserted-by":"publisher"}],"name":"Mahidol University","place":["Thailand"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"24","reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1152\/ajplegacy.1957.189.3.609"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1007\/s10286-004-0180-4"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1097\/01.ccm.0000134348.69165.15"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2004.076422"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00458.2016"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1113\/EP086654"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1152\/ajplegacy.1951.167.3.738"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1990.69.6.1961"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm\/146.1.4"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1513\/AnnalsATS.201704-339FR"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0005550"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00576.2010"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2015.00411"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1109\/EMBC44109.2020.9176170"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1113\/EP089180"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1113\/JP283176"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1113\/JP284068"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1113\/JP284136"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1161\/01.res.58.2.281"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1136\/bjsm.2004.013037"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2342-9-2"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1987.62.5.2003"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00241.2001"},{"key":"B24","unstructured":"Montebelli.\n                      Effects of expiratory flow limitation on mechanical cardio-pulmonary interactions: a model study\n                      . Milan, Italy: Politecnico di Milano, 2005."},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.5507\/bp.2006.015"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.2001.281.6.H2661"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-201x.2000.00703.x"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1111\/cpf.12596"},{"key":"B29","volume-title":"ACSM\u2019s Advanced Exercise Physiology","author":"Farrell PA","year":"2011","edition":"2"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1093\/ehjci\/jeu022"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00750.2021"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1007\/s004210000226"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.1979.237.4.H491"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.90600.2008"},{"key":"B35","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-009-1445-0"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.1212\/wnl.49.2.507"},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2011.02.015"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.1016\/j.soard.2009.04.003"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.1080\/01443615.2020.1820470"},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2005.042473"},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1843.2007.01106.x"},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00058.2024"},{"key":"B43","first-page":"273","volume":"2","author":"Shujaat A","year":"2007","journal-title":"Int J Chron Obstruct Pulmon Dis"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.1016\/j.carpath.2011.11.007"},{"key":"B45","doi-asserted-by":"publisher","DOI":"10.1113\/EP091387"},{"key":"B46","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0065146"},{"key":"B47","doi-asserted-by":"publisher","DOI":"10.3390\/aerospace7080105"},{"key":"B48","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-82567-9"},{"key":"B49","doi-asserted-by":"publisher","DOI":"10.1109\/tbme.1975.324508"},{"key":"B50","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-374407-4.00410-6"}],"container-title":["Journal of Applied Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.physiology.org\/doi\/pdf\/10.1152\/japplphysiol.00749.2024","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,16]],"date-time":"2025-06-16T14:16:36Z","timestamp":1750083396000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.physiology.org\/doi\/10.1152\/japplphysiol.00749.2024"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,1]]},"references-count":50,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,6,1]]}},"alternative-id":["10.1152\/japplphysiol.00749.2024"],"URL":"https:\/\/doi.org\/10.1152\/japplphysiol.00749.2024","relation":{},"ISSN":["8750-7587","1522-1601"],"issn-type":[{"value":"8750-7587","type":"print"},{"value":"1522-1601","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6,1]]},"assertion":[{"value":"2024-09-26","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-10-22","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-05-14","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-16","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}