{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T11:24:55Z","timestamp":1789730695927,"version":"4.0.1"},"reference-count":43,"publisher":"American Physiological Society","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Applied Physiology"],"published-print":{"date-parts":[[2005,12]]},"DOI":"10.1152\/japplphysiol.01205.2004","type":"journal-article","created":{"date-parts":[[2005,8,19]],"date-time":"2005-08-19T00:33:54Z","timestamp":1124411634000},"page":"2108-2114","source":"Crossref","is-referenced-by-count":46,"title":["Effects of chronic hypoxia on MK-801-induced changes in the acute hypoxic ventilatory response"],"prefix":"10.1152","volume":"99","author":[{"given":"Stephen G.","family":"Reid","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank L.","family":"Powell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"24","reference":[{"key":"R1","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1993.74.4.1635"},{"key":"R2","unstructured":"Bisgard GEand Neubauer JA.Peripheral and central effects of hypoxia. In:Regulation of Breathing, edited by Dempsey JA and Pack AI. New York: Dekker, 1995."},{"key":"R3","doi-asserted-by":"publisher","DOI":"10.1016\/S0034-5687(00)00131-6"},{"key":"R4","doi-asserted-by":"publisher","DOI":"10.1016\/0034-5687(95)00045-F"},{"key":"R5","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-2999(98)00160-5"},{"key":"R6","doi-asserted-by":"publisher","DOI":"10.1016\/0306-4522(96)00112-1"},{"key":"R7","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(95)00205-5"},{"key":"R8","doi-asserted-by":"crossref","unstructured":"Coles SK, Ernsbergher P, and Dick TE.A role for NMDA receptors in posthypoxic frequency decline in the rat.Am J Physiol Regul Integr Comp Physiol274: R1546\u2013R1555, 1998.","DOI":"10.1152\/ajpregu.1998.274.6.R1546"},{"key":"R9","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(92)91537-O"},{"key":"R10","doi-asserted-by":"crossref","unstructured":"Czapla MC, Simakajornboon N, Holt GA, and Gozal D.Tyrosine kinase inhibitors modulate the ventilatory response to hypoxia in the conscious rat.J Appl Physiol87: 363\u2013369, 1999.","DOI":"10.1152\/jappl.1999.87.1.363"},{"key":"R11","doi-asserted-by":"crossref","unstructured":"Dempsey JAand Forster HV.Mediation of ventilatory adaptations.Physiol Rev62: 262\u2013346, 1982.","DOI":"10.1152\/physrev.1982.62.1.262"},{"key":"R12","doi-asserted-by":"crossref","unstructured":"Drorbaugh JEand Fenn WO.A barometric method of measuring ventilation in newborn infants.Pediatrics16: 81\u201389, 1955.","DOI":"10.1001\/archpedi.1955.02050110681007"},{"key":"R13","doi-asserted-by":"crossref","unstructured":"Dwinell MRand Powell FL.Chronic hypoxia enhances the phrenic nerve response to arterial chemoreceptor stimulation in anaesthetized rats.J Appl Physiol87: 818\u2013823, 1999.","DOI":"10.1152\/jappl.1999.87.2.817"},{"key":"R14","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(92)90458-L"},{"key":"R15","unstructured":"Forster HVand Dempsey JA.Ventilatory adaptations. In:Regulation of Breathing, edited by Hornbein TF. New York: Dekker, 1981, p. 845\u2013904."},{"key":"R16","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(89)90314-4"},{"key":"R17","doi-asserted-by":"publisher","DOI":"10.1016\/S0024-3205(01)01319-4"},{"key":"R18","doi-asserted-by":"publisher","DOI":"10.1016\/0034-5687(94)90125-2"},{"key":"R19","doi-asserted-by":"publisher","DOI":"10.1016\/S0034-5687(98)00038-3"},{"key":"R20","doi-asserted-by":"crossref","unstructured":"Gozal D, Holt GA, Graff GR, and Torres JE.Platelet-activating factor modulates cardiorespiratory responses in the conscious rat.Am J Physiol Regul Integr Comp Physiol275: R604\u2013R611, 1998.","DOI":"10.1152\/ajpregu.1998.275.2.R604"},{"key":"R21","doi-asserted-by":"crossref","unstructured":"Gozal E, Roussel AL, Holt GA, Gozal L, Gozal YM, Torres JE, and Gozal D.Protein kinase C modulation of ventilatory response to hypoxia in nucleus tractus solitarii of conscious rats.J Appl Physiol84: 1982\u20131990, 1998.","DOI":"10.1152\/jappl.1998.84.6.1982"},{"key":"R22","doi-asserted-by":"publisher","DOI":"10.1016\/S0034-5687(00)00129-8"},{"key":"R23","doi-asserted-by":"publisher","DOI":"10.1016\/S0034-5687(00)00219-X"},{"key":"R24","doi-asserted-by":"publisher","DOI":"10.1016\/S1569-9048(02)00223-9"},{"key":"R25","doi-asserted-by":"publisher","DOI":"10.1016\/S0034-5687(98)00087-5"},{"key":"R26","doi-asserted-by":"crossref","unstructured":"Housley GDand Sinclair JD.Localization by kainic acid lesions of neurons transmitting the carotid chemoreceptor stimulus for respiration in rats.J Physiol406: 99\u2013114, 1998.","DOI":"10.1113\/jphysiol.1988.sp017371"},{"key":"R27","doi-asserted-by":"crossref","unstructured":"Jacky JP.A plethysmograph for long-term measurement of ventilation in unrestrained animals.J Appl Physiol45: 644\u2013647, 1978.","DOI":"10.1152\/jappl.1978.45.4.644"},{"key":"R28","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-1838(99)00054-5"},{"key":"R29","doi-asserted-by":"publisher","DOI":"10.1016\/S0306-4522(00)00435-8"},{"key":"R30","doi-asserted-by":"crossref","unstructured":"Ling L, Karius DR, and Speck DF.Role ofN-methyl-d-aspartate receptors in the pontine pneumotaxic mechanisms in the cat.J Appl Physiol76: 1138\u20131143, 1994.","DOI":"10.1152\/jappl.1994.76.3.1138"},{"key":"R31","doi-asserted-by":"publisher","DOI":"10.1016\/0034-5687(73)90108-4"},{"key":"R32","doi-asserted-by":"publisher","DOI":"10.1590\/S0100-879X1998000700002"},{"key":"R33","unstructured":"McCrimmon DR, Dekin MS, and Mitchell GS.Glutamate, GABA and serotonin in ventilatory control. In:Regulation of Breathing, edited by Dempsey JA and Pack AI. New York: Dekker, 1995, p. 151\u2013218."},{"key":"R34","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1994.sp020229"},{"key":"R35","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3940(90)90551-J"},{"key":"R36","doi-asserted-by":"publisher","DOI":"10.1139\/y99-001"},{"key":"R37","doi-asserted-by":"crossref","unstructured":"Ohtake PJ, Torres JE, Gozal YM, Graff GR, and Gozal D.NMDA receptors mediate peripheral chemoreceptor afferent input in the conscious rat.J Appl Physiol84: 853\u2013861, 1998.","DOI":"10.1152\/jappl.1998.84.3.853"},{"key":"R38","doi-asserted-by":"publisher","DOI":"10.1016\/S0034-5687(98)00026-7"},{"key":"R39","doi-asserted-by":"publisher","DOI":"10.1016\/S0034-5687(00)00130-4"},{"key":"R40","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00759.2002"},{"key":"R41","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1994.sp020194"},{"key":"R42","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1997.82.1.317"},{"key":"R43","doi-asserted-by":"crossref","unstructured":"Vardhan A, Kachroo A, and Sapru NH.Excitatory amino acid receptors in commissural nucleus of the NTS mediate carotid chemoreceptor responses.Am J Physiol Regul Integr Comp Physiol264: R41\u2013R50, 1993.","DOI":"10.1152\/ajpregu.1993.264.1.R41"}],"container-title":["Journal of Applied Physiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.physiology.org\/doi\/pdf\/10.1152\/japplphysiol.01205.2004","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,4,9]],"date-time":"2020-04-09T02:44:49Z","timestamp":1586400289000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.physiology.org\/doi\/10.1152\/japplphysiol.01205.2004"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,12]]},"references-count":43,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2005,12]]}},"alternative-id":["10.1152\/japplphysiol.01205.2004"],"URL":"https:\/\/doi.org\/10.1152\/japplphysiol.01205.2004","relation":{},"ISSN":["8750-7587","1522-1601"],"issn-type":[{"value":"8750-7587","type":"print"},{"value":"1522-1601","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,12]]}}}