{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T13:49:26Z","timestamp":1792158566596,"version":"4.4.0"},"reference-count":89,"publisher":"American Physiological Society","issue":"4","funder":[{"DOI":"10.13039\/100000055","name":"HHS | NIH | National Institute on Deafness and Other Communication Disorders","doi-asserted-by":"publisher","award":["R21DC019711"],"award-info":[{"award-number":["R21DC019711"]}],"id":[{"id":"10.13039\/100000055","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000055","name":"HHS | NIH | National Institute on Deafness and Other Communication Disorders","doi-asserted-by":"publisher","award":["F31DC022802"],"award-info":[{"award-number":["F31DC022802"]}],"id":[{"id":"10.13039\/100000055","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000065","name":"HHS | NIH | National Institute of Neurological Disorders and Stroke","doi-asserted-by":"publisher","award":["R34NS137017"],"award-info":[{"award-number":["R34NS137017"]}],"id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"HHS | NIH | National Institute on Aging","doi-asserted-by":"publisher","award":["T32AG087922"],"award-info":[{"award-number":["T32AG087922"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"HHS | NIH | National Institute on Aging","doi-asserted-by":"publisher","award":["U24AG072122"],"award-info":[{"award-number":["U24AG072122"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000957","name":"Alzheimer's Association","doi-asserted-by":"publisher","award":["U24AG072122"],"award-info":[{"award-number":["U24AG072122"]}],"id":[{"id":"10.13039\/100000957","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100018580","name":"National Alzheimer's Coordinating Center","doi-asserted-by":"publisher","award":["U24AG072122"],"award-info":[{"award-number":["U24AG072122"]}],"id":[{"id":"10.13039\/100018580","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100001391","name":"Whitehall Foundation","doi-asserted-by":"publisher","award":["2022-12-024"],"award-info":[{"award-number":["2022-12-024"]}],"id":[{"id":"10.13039\/100001391","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.physiology.org"],"crossmark-restriction":true},"short-container-title":["Journal of Neurophysiology"],"published-print":{"date-parts":[[2026,10,1]]},"abstract":"<jats:p>We present Open-source System for ABR (OpenSABR), a new and open-source system for recording the auditory brainstem response (ABR) that costs about 50-fold less than some commercial alternatives. All hardware designs, software, and data are freely available. We demonstrate high-quality recordings in mice and new methods for quantifying the ABR, and we show that OpenSABR can detect threshold changes after hearing loss.<\/jats:p>","DOI":"10.1152\/jn.00125.2026","type":"journal-article","created":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T23:51:02Z","timestamp":1788997862000},"page":"1369-1386","update-policy":"https:\/\/doi.org\/10.1152\/aps-crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Assessing hearing and hearing loss in mice with OpenSABR (Open-source System for Auditory Brainstem Response)"],"prefix":"10.1152","volume":"136","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-3666-5204","authenticated-orcid":false,"given":"Rowan","family":"Gargiullo","sequence":"first","affiliation":[{"name":"Emory University","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9988-5168","authenticated-orcid":false,"given":"Cedric","family":"Bowe","sequence":"additional","affiliation":[{"name":"Emory University","place":["United States"]},{"name":"Emory University","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abigail F.","family":"McElroy","sequence":"additional","affiliation":[{"name":"Emory University","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica","family":"Mai","sequence":"additional","affiliation":[{"name":"Emory University","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4087-3052","authenticated-orcid":false,"given":"William N.","family":"Goolsby","sequence":"additional","affiliation":[{"name":"Emory University","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1762-3450","authenticated-orcid":false,"given":"Chris C.","family":"Rodgers","sequence":"additional","affiliation":[{"name":"Emory University","place":["United States"]},{"name":"Emory University","place":["United States"]},{"name":"Emory University","place":["United States"]},{"name":"Emory University and the Georgia Institute of Technology","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"24","reference":[{"key":"B1","volume-title":"Handbook of auditory evoked responses","author":"Hall JW","year":"1992"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-199506000-00007"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1016\/s0378-5955(99)00003-9"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2015.12.041"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-04852-y"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1007\/s10162-015-0539-3"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2018.08.023"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1016\/j.jneumeth.2005.10.017"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1016\/j.heares.2019.107782"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2006.01.107"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1783-13.2013"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1016\/j.heares.2016.08.008"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1016\/j.heares.2012.04.005"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.3109\/00206099009072847"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1159\/000259203"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1211-18.2018"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.0837-15.2015"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1007\/s10162-018-0671-y"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1098\/rspb.2022.0878"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1016\/0378-5955(95)00178-6"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1016\/0378-5955(95)00179-4"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1016\/0378-5955(95)00200-6"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbpa.2009.02.040"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2023.1106570"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1111\/gbb.12370"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2019.134705"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199909000-00001"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1992-07.2007"},{"key":"B29","doi-asserted-by":"publisher","unstructured":"Lu C, Linden JF. Distinct effects of sensory and genetic risk factors for psychosis on auditory cortical temporal acuity in a mouse model of 22q11.2 Deletion Syndrome (Preprint). bioRxiv, 2026.03.26.714426, 2026. doi:10.64898\/2026.03.26.714426v2.","DOI":"10.64898\/2026.03.26.714426v2"},{"key":"B30","doi-asserted-by":"publisher","unstructured":"Van Den Broucke A, Van Kerrebrouck J, Van Ransbeeck W, Pynckels R, Fr\u00e1ter A, Torfs G, et al Wireless and wearable auditory EEG acquisition hardware using around-the-ear cEEGrid electrodes. 2023 45th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC). Sydney, Australia, 2023, p. 1\u20134. doi:10.1109\/EMBC40787.2023.10340180. 38083060","DOI":"10.1109\/EMBC40787.2023.10340180"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.3389\/fnhum.2020.00078"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1088\/1361-6579\/abcdf2"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1109\/TBCAS.2023.3272649"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-41895-7"},{"key":"B35","author":"Gargiullo R","year":"2025","journal-title":"Zenodo"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-374245-2.00029-2"},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.5281\/zenodo.3925902"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.1017\/9781009039826"},{"key":"B39","volume-title":"Biomedical Engineering Handbook","author":"Nagel JH","year":"2000"},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/94.4.681"},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.1016\/j.neurobiolaging.2016.05.001"},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.1002\/0471142301.ns0821bs34"},{"key":"B43","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.0651-25.2025"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.1016\/j.anorl.2023.04.003"},{"key":"B45","doi-asserted-by":"publisher","DOI":"10.1088\/1741-2552\/aa5eea"},{"key":"B46","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.3000410"},{"key":"B47","doi-asserted-by":"publisher","DOI":"10.1523\/ENEURO.0513-21.2022"},{"key":"B48","doi-asserted-by":"publisher","DOI":"10.1016\/j.neurobiolaging.2009.09.009"},{"key":"B49","doi-asserted-by":"publisher","DOI":"10.21769\/bioprotoc.1768"},{"key":"B50","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-0716-2022-9_16"},{"key":"B51","doi-asserted-by":"publisher","DOI":"10.1016\/j.heares.2004.02.009"},{"key":"B52","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.2103-24.2025"},{"key":"B53","doi-asserted-by":"publisher","DOI":"10.1016\/j.heares.2012.08.010"},{"key":"B54","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/9161040"},{"key":"B55","doi-asserted-by":"publisher","unstructured":"Wallace DJ, Holmgren C, Czubayko U, Klesing J, Machado DM, Kerr JND. Acute obstructive uropathy in male C57Bl\/6 mice after general anesthesia with fentanyl, midazolam and medetomidine (Preprint). bioRxiv, 2025. doi:10.1101\/2025.02.12.636996.","DOI":"10.1101\/2025.02.12.636996"},{"key":"B56","doi-asserted-by":"publisher","unstructured":"Saunders JL, Ott LA, Wehr M. AUTOPILOT: automating experiments with lots of Raspberry Pis (Preprint). bioRxiv, 2019. doi:10.1101\/807693.","DOI":"10.1101\/807693"},{"key":"B57","doi-asserted-by":"publisher","DOI":"10.1007\/s10162-020-00754-3"},{"key":"B58","doi-asserted-by":"publisher","DOI":"10.1016\/j.heares.2012.10.004"},{"key":"B59","doi-asserted-by":"publisher","DOI":"10.1016\/j.heares.2011.12.004"},{"key":"B60","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0264.2009.00946.x"},{"key":"B61","doi-asserted-by":"publisher","DOI":"10.3791\/55054"},{"key":"B62","doi-asserted-by":"publisher","DOI":"10.1186\/s40463-018-0265-z"},{"key":"B63","volume":"40","author":"Lai P","year":"2011","journal-title":"Journal of Otolaryngology - Head and Neck Surgery"},{"key":"B64","doi-asserted-by":"publisher","DOI":"10.1109\/MCSE.2007.53"},{"key":"B65","doi-asserted-by":"crossref","unstructured":"McKinney W. Data Structures for Statistical Computing in Python. Austin, Texas, 2010 [cited 2026 Jul 16]. p. 56\u201361. Available from: https:\/\/doi.curvenote.com\/10.25080\/Majora-92bf1922-00a.","DOI":"10.25080\/Majora-92bf1922-00a"},{"key":"B66","doi-asserted-by":"publisher","DOI":"10.1109\/MCSE.2011.37"},{"key":"B67","doi-asserted-by":"publisher","DOI":"10.1038\/s41592-019-0686-2"},{"key":"B68","doi-asserted-by":"publisher","unstructured":"Seabold S, Perktold J. Statsmodels: econometric and statistical modeling with Python. In: Proceedings of the 9th Python in Science Conference. 2010. p. 92\u201396. doi:10.25080\/majora-92bf1922-011.","DOI":"10.25080\/majora-92bf1922-011"},{"key":"B69","doi-asserted-by":"publisher","DOI":"10.1109\/MCSE.2007.55"},{"key":"B70","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-026-38045-1"},{"key":"B71","doi-asserted-by":"publisher","DOI":"10.1016\/j.heares.2025.109258"},{"key":"B72","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2014.279380"},{"key":"B73","doi-asserted-by":"publisher","DOI":"10.1121\/1.411281"},{"key":"B74","volume-title":"A Wavelet Tour of Signal Processing","author":"Mallat S","year":"1998"},{"key":"B75","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-92495-3_5"},{"key":"B76","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00026.2009"},{"key":"B77","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2019.09.010"},{"key":"B78","doi-asserted-by":"publisher","DOI":"10.12659\/MSM.936373"},{"key":"B79","doi-asserted-by":"publisher","DOI":"10.1038\/s41592-024-02521-1"},{"key":"B80","doi-asserted-by":"publisher","DOI":"10.1088\/1741-2552\/ab77fa"},{"key":"B81","doi-asserted-by":"publisher","DOI":"10.1523\/ENEURO.0223-19.2019"},{"key":"B82","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.3000014"},{"key":"B83","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2019.00477"},{"key":"B84","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-024-67577-7"},{"key":"B85","doi-asserted-by":"publisher","DOI":"10.1038\/s41593-026-02262-8"},{"key":"B86","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2024.02.057"},{"key":"B87","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2025.10.017"},{"key":"B88","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2025.106926"},{"key":"B89","first-page":"173","volume":"4","author":"Henry KR","year":"1979","journal-title":"J Am Aud Soc"}],"container-title":["Journal of Neurophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.physiology.org\/doi\/pdf\/10.1152\/jn.00125.2026","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T13:08:53Z","timestamp":1792156133000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.physiology.org\/doi\/10.1152\/jn.00125.2026"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10,1]]},"references-count":89,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,10,1]]}},"alternative-id":["10.1152\/jn.00125.2026"],"URL":"https:\/\/doi.org\/10.1152\/jn.00125.2026","relation":{},"ISSN":["0022-3077","1522-1598"],"issn-type":[{"value":"0022-3077","type":"print"},{"value":"1522-1598","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,1]]},"assertion":[{"value":"2026-03-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-12","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-01","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-21","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}