{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T17:47:22Z","timestamp":1785520042719,"version":"3.56.0"},"reference-count":44,"publisher":"American Physiological Society","issue":"2","funder":[{"DOI":"10.13039\/501100006087","name":"UNAM | Direcci\u00f3n General de Asuntos del Personal Acad\u00e9mico, Universidad Nacional Aut\u00f3noma de M\u00e9xico","doi-asserted-by":"publisher","award":["IN208725"],"award-info":[{"award-number":["IN208725"]}],"id":[{"id":"10.13039\/501100006087","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006087","name":"UNAM | Direcci\u00f3n General de Asuntos del Personal Acad\u00e9mico, Universidad Nacional Aut\u00f3noma de M\u00e9xico","doi-asserted-by":"publisher","award":["PASPA"],"award-info":[{"award-number":["PASPA"]}],"id":[{"id":"10.13039\/501100006087","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006087","name":"UNAM | Direcci\u00f3n General de Asuntos del Personal Acad\u00e9mico, Universidad Nacional Aut\u00f3noma de M\u00e9xico","doi-asserted-by":"publisher","award":["IN224624"],"award-info":[{"award-number":["IN224624"]}],"id":[{"id":"10.13039\/501100006087","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.physiology.org"],"crossmark-restriction":true},"short-container-title":["Journal of Neurophysiology"],"published-print":{"date-parts":[[2026,8,1]]},"abstract":"<jats:p>To understand the olfactory and cognitive deficits observed in viral rhinitis, we described the impact of nasal inflammation, induced by the viral mimetic poly(I:C), on the circuit composed of the olfactory bulb and entorhinal cortex by measuring their individual neural network activities and their functional connectivity in the absence and presence of odors. We also evaluated signs of neuroinflammation in both structures and the animals\u2019 olfaction, revealing pathological mechanisms behind neurological manifestations associated with rhinitis.<\/jats:p>","DOI":"10.1152\/jn.00129.2026","type":"journal-article","created":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T14:51:37Z","timestamp":1784213497000},"page":"643-652","update-policy":"https:\/\/doi.org\/10.1152\/aps-crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Intranasal poly(I:C)-induced inflammation alters olfactory bulb-entorhinal cortex circuit and its coupling to breathing"],"prefix":"10.1152","volume":"136","author":[{"given":"C\u00e9sar Alexander","family":"Zaa","sequence":"first","affiliation":[{"name":"Universidad Nacional Aut\u00f3noma de M\u00e9xico","place":["M\u00e9xico"]},{"name":"Posgrado en Ciencias Biol\u00f3gicas, UNAM","place":["M\u00e9xico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8032-806X","authenticated-orcid":false,"given":"Ricardo Jair","family":"Ram\u00edrez-Carreto","sequence":"additional","affiliation":[{"name":"Universidad Nacional Aut\u00f3noma de M\u00e9xico","place":["M\u00e9xico"]},{"name":"Universidad Nacional Aut\u00f3noma de M\u00e9xico","place":["M\u00e9xico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6185-0226","authenticated-orcid":false,"given":"Benito","family":"Ordaz-S\u00e1nchez","sequence":"additional","affiliation":[{"name":"Universidad Nacional Aut\u00f3noma de M\u00e9xico","place":["M\u00e9xico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6412-0461","authenticated-orcid":false,"given":"Anah\u00ed","family":"Chavarr\u00eda","sequence":"additional","affiliation":[{"name":"Universidad Nacional Aut\u00f3noma de M\u00e9xico","place":["M\u00e9xico"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0348-4392","authenticated-orcid":false,"given":"Fernando","family":"Pe\u00f1a-Ortega","sequence":"additional","affiliation":[{"name":"Universidad Nacional Aut\u00f3noma de M\u00e9xico","place":["M\u00e9xico"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"24","reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1111\/all.13200"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0221978"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.3390\/jcm10143183"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1007\/s00441-014-1848-2"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1186\/s12974-022-02378-1"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1002\/alr.21581"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1111\/cea.12893"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2021.147368"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.02044-14"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9975(97)80078-3"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-022-07809-w"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1016\/j.resp.2021.103835"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.2006994"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-022-28090-5"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1016\/j.autneu.2018.11.002"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbi.2023.08.004"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1007\/s10753-026-02467-w"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1186\/s12576-021-00805-1"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2023.08.072"},{"key":"B20","doi-asserted-by":"publisher","unstructured":"Mena W, Baker K, Rubin A, Kohli S, Yoo Y, Bathellier B, Ziv Y, Rezaei-Mazinani S, Fleischmann A. Differential encoding of odor and place in mouse piriform and entorhinal cortex (Preprint). bioRxiv, 2025. doi:10.1101\/2023.10.05.561119.39829902","DOI":"10.1101\/2023.10.05.561119"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.3389\/fnana.2018.00115"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0332592"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1007\/s12035-025-05299-1"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1038\/s41386-020-0743-7"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.3046-10.2010"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0029754"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1038\/srep19106"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1248\/bpb.b19-00028"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0075745"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/3424906"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.1111\/ejn.15610"},{"key":"B32","volume-title":"The Mouse Brain in Stereotaxic Coordinates","author":"Paxinos GF","year":"2001","edition":"2"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1016\/j.expneurol.2021.113653"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.1007\/s11064-025-04510-y"},{"key":"B35","doi-asserted-by":"publisher","DOI":"10.2174\/156720512802455403"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.2174\/1567205015666180223091233"},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.3389\/fnagi.2022.903455"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.1002\/glia.10161"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.2174\/1567205017666191213162233"},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.1002\/lary.22190"},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awn345"},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.1016\/j.tins.2018.01.007"},{"key":"B43","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00458.2024"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.1155\/2023\/4637073"}],"container-title":["Journal of Neurophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.physiology.org\/doi\/pdf\/10.1152\/jn.00129.2026","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T16:55:56Z","timestamp":1785516956000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.physiology.org\/doi\/10.1152\/jn.00129.2026"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,1]]},"references-count":44,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,8,1]]}},"alternative-id":["10.1152\/jn.00129.2026"],"URL":"https:\/\/doi.org\/10.1152\/jn.00129.2026","relation":{},"ISSN":["0022-3077","1522-1598"],"issn-type":[{"value":"0022-3077","type":"print"},{"value":"1522-1598","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,1]]},"assertion":[{"value":"2026-03-26","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-04","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-03","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-31","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}