{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T14:12:59Z","timestamp":1761401579822},"reference-count":55,"publisher":"American Physiological Society","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Neurophysiology"],"published-print":{"date-parts":[[2012,3,1]]},"abstract":"<jats:p> The medial olivocochlear (MOC) bundle reduces the gain of the cochlear amplifier through reflexive activation by sound. Physiological results indicate that MOC-induced reduction in cochlear gain can enhance the response to signals when presented in masking noise. Some previous studies suggest that this \u201cantimasking\u201d effect of the MOC system plays a role in speech-in-noise perception. The present study set out to reinvestigate this hypothesis by correlating measures of MOC activity and speech-in-noise processing across a group of normal-hearing participants. MOC activity was measured using contralateral suppression of otoacoustic emissions (OAEs), and speech-in-noise processing was measured by measuring the effect of noise masking on performance in a consonant-vowel (CV) discrimination task and on auditory brain stem responses evoked by a CV syllable. Whereas there was a significant correlation between OAE suppression and both measures of speech-in-noise processing, the direction of this correlation was opposite to that predicted by the antimasking hypothesis, in that individuals with stronger OAE suppression tended to show greater noise-masking effects on CV processing. The current results indicate that reflexive MOC activation is not always beneficial to speech-in-noise processing. We propose an alternative to the antimasking hypothesis, whereby the MOC system benefits speech-in-noise processing through dynamic (e.g., attention- and experience-dependent), rather than reflexive, control of cochlear gain. <\/jats:p>","DOI":"10.1152\/jn.00222.2011","type":"journal-article","created":{"date-parts":[[2011,12,9]],"date-time":"2011-12-09T01:39:51Z","timestamp":1323394791000},"page":"1301-1312","source":"Crossref","is-referenced-by-count":68,"title":["What is the role of the medial olivocochlear system in speech-in-noise processing?"],"prefix":"10.1152","volume":"107","author":[{"given":"Jessica","family":"de Boer","sequence":"first","affiliation":[{"name":"MRC Institute of Hearing Research, Nottingham; and"},{"name":"MRC Institute of Hearing Research Southampton Section, Southampton, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. 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