{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T10:29:55Z","timestamp":1785407395186,"version":"3.56.0"},"reference-count":72,"publisher":"American Physiological Society","issue":"2","license":[{"start":{"date-parts":[[2025,1,21]],"date-time":"2025-01-21T00:00:00Z","timestamp":1737417600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100024571","name":"KU | Novo Nordisk Foundation Center for Protein Research, University of Copenhagen","doi-asserted-by":"publisher","award":["NNF19OC0058681"],"award-info":[{"award-number":["NNF19OC0058681"]}],"id":[{"id":"10.13039\/501100024571","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.physiology.org"],"crossmark-restriction":true},"short-container-title":["Journal of Neurophysiology"],"published-print":{"date-parts":[[2025,2,1]]},"abstract":"<jats:p>\n                    The calcium channel antagonist nimodipine significantly reduces the size of the soleus H reflex and stretch reflex in healthy individuals without affecting maximum direct motor response (M\n                    <jats:sub>max<\/jats:sub>\n                    ) or the stretch reflex during voluntary activation. This underscores the importance of exploring nimodipine as a potential antispastic medication in the future.\n                  <\/jats:p>","DOI":"10.1152\/jn.00585.2024","type":"journal-article","created":{"date-parts":[[2024,12,24]],"date-time":"2024-12-24T10:32:36Z","timestamp":1735036356000},"page":"428-439","update-policy":"https:\/\/doi.org\/10.1152\/aps-crossmark-policy","source":"Crossref","is-referenced-by-count":1,"title":["The calcium channel blocker nimodipine inhibits spinal reflex pathways in humans"],"prefix":"10.1152","volume":"133","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4797-1050","authenticated-orcid":false,"given":"Eva Rudjord","family":"Therkildsen","sequence":"first","affiliation":[{"id":[{"id":"https:\/\/ror.org\/035b05819","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Copenhagen","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5568-2916","authenticated-orcid":false,"given":"Jens Bo","family":"Nielsen","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/035b05819","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Copenhagen","place":["Denmark"]},{"name":"The Elsass FoundationCharlottenlundDenmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7634-0218","authenticated-orcid":false,"given":"Jakob","family":"Lorentzen","sequence":"additional","affiliation":[{"id":[{"id":"https:\/\/ror.org\/035b05819","id-type":"ROR","asserted-by":"publisher"}],"name":"University of Copenhagen","place":["Denmark"]},{"name":"Rigshospitalet","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"24","reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1037\/13798-000"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1007\/s002219900250"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-neuro-070815-013913"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1016\/j.pneurobio.2006.04.001"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7793.1999.203ad.x"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1988.sp017336"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1007\/BF00236551"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.20-17-06734.2000"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1989.sp017687"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2005.099119"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00391.2005"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00236.2003"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2009.12.041"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1089\/neu.1999.16.69"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00946.2003"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1152\/jn.2001.86.4.1972"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.23011"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1038\/nm.2160"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1152\/jn.01011.2010"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00775.2010"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.aay0167"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1152\/jn.1997.78.6.3061"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awh243"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00024.2001"},{"key":"B25","doi-asserted-by":"publisher","unstructured":"Beauchamp JA, Pearcey GE, Khurram OU, Negro F, Dewald JP, Heckman CJ. Intrinsic properties of spinal motoneurons degrade ankle torque control in humans (Preprint). bioRxiv 2023.10.23.563670, 2023. doi:10.1101\/2023.10.23.563670.","DOI":"10.1101\/2023.10.23.563670"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awh073"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-3940(98)00277-8"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00204.2024"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00822.2012"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00821.2012"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.1113\/JP284164"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.2165\/00003495-198937050-00004"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1016\/j.cnp.2016.02.003"},{"key":"B34","first-page":"485","volume-title":"Spasticity: Disordered Motor Control","author":"Lance JW","year":"1980"},{"key":"B35","doi-asserted-by":"publisher","DOI":"10.1111\/j.1094-7159.2005.05220.x"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.1016\/S0301-0082(00)00007-1"},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.1152\/jn.1992.67.5.1375"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.1017\/CBO9781139026727.010"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.1016\/j.pmrj.2016.11.002"},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.1177\/0883073814535504"},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.1007\/BF00248294"},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.1016\/0028-3908(94)90015-9"},{"key":"B43","doi-asserted-by":"publisher","DOI":"10.1152\/jn.1984.52.3.435"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1983.sp014732"},{"key":"B45","doi-asserted-by":"publisher","DOI":"10.1152\/jn.1998.80.2.610"},{"key":"B46","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7793.2001.00925.x"},{"key":"B47","doi-asserted-by":"publisher","DOI":"10.1152\/jn.1991.65.6.1402"},{"key":"B48","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7793.1998.267bf.x"},{"key":"B49","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7793.1997.473bn.x"},{"key":"B50","doi-asserted-by":"publisher","DOI":"10.3389\/fncir.2021.642111"},{"key":"B51","doi-asserted-by":"publisher","DOI":"10.1007\/s00221-012-3053-4"},{"key":"B52","doi-asserted-by":"publisher","DOI":"10.1016\/S1388-2457(00)00352-7"},{"key":"B53","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.56.5.515"},{"key":"B54","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410170119"},{"key":"B55","doi-asserted-by":"publisher","DOI":"10.1152\/jn.1998.79.1.45"},{"key":"B56","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7793.1998.795bv.x"},{"key":"B57","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00164.2004"},{"key":"B58","doi-asserted-by":"publisher","DOI":"10.1177\/135245850000600209"},{"key":"B59","doi-asserted-by":"publisher","DOI":"10.1124\/pr.114.009654"},{"key":"B60","doi-asserted-by":"publisher","DOI":"10.1111\/bph.16060"},{"key":"B61","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.21-16-05944.2001"},{"key":"B62","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00788.2003"},{"key":"B63","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awn050"},{"key":"B64","doi-asserted-by":"publisher","DOI":"10.1097\/01.WNP.0000158948.00901.4E"},{"key":"B65","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awq053"},{"key":"B66","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awn310"},{"key":"B67","doi-asserted-by":"publisher","DOI":"10.1017\/S0317167100032133"},{"key":"B68","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.47.10.1102"},{"key":"B69","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0404.1995.tb06997.x"},{"key":"B70","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/116.4.971"},{"key":"B71","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00372.2013"},{"key":"B72","doi-asserted-by":"publisher","DOI":"10.1111\/j.1094-7159.2005.05220.x"}],"container-title":["Journal of Neurophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.physiology.org\/doi\/pdf\/10.1152\/jn.00585.2024","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,10]],"date-time":"2025-04-10T14:59:42Z","timestamp":1744297182000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.physiology.org\/doi\/10.1152\/jn.00585.2024"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,1]]},"references-count":72,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,2,1]]}},"alternative-id":["10.1152\/jn.00585.2024"],"URL":"https:\/\/doi.org\/10.1152\/jn.00585.2024","relation":{},"ISSN":["0022-3077","1522-1598"],"issn-type":[{"value":"0022-3077","type":"print"},{"value":"1522-1598","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,2,1]]},"assertion":[{"value":"2024-12-10","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-12-17","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-12-17","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-01-21","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}