{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T03:10:39Z","timestamp":1790737839526,"version":"4.1.0"},"reference-count":22,"publisher":"American Physiological Society","issue":"2","funder":[{"DOI":"10.13039\/100000025","name":"National Institutes of Mental Health","doi-asserted-by":"crossref","award":["F32 MH114325"],"award-info":[{"award-number":["F32 MH114325"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["journals.physiology.org"],"crossmark-restriction":true},"short-container-title":["Journal of Neurophysiology"],"published-print":{"date-parts":[[2021,2,1]]},"abstract":"<jats:p> In a recent study published in The Journal of Neurophysiology, Ehrardt et al. (Ehrhardt SE, Filmer HL, Wards Y, Mattingley JB, Dux PE. J Neurophysiol 125: 385\u2013397, 2021) report that moderate intensity (1\u2009mA\/25 cm<jats:sup>2<\/jats:sup>) transcranial direct current stimulation (tDCS) is optimal for improving performance on a stimulus-response matching task, as opposed to a lower 0.7\u2009mA\/25 cm<jats:sup>2<\/jats:sup> or higher 2\u2009mA\/25 cm<jats:sup>2<\/jats:sup> dose. This result suggests that behavioral effects of tDCS do not follow a linear dose-response curve. Potential neurobiological and neurocognitive implications of these findings, as well as suggested directions for future research, are discussed. <\/jats:p>","DOI":"10.1152\/jn.00652.2020","type":"journal-article","created":{"date-parts":[[2021,1,6]],"date-time":"2021-01-06T21:03:19Z","timestamp":1609966999000},"page":"606-608","update-policy":"https:\/\/doi.org\/10.1152\/aps-crossmark-policy","source":"Crossref","is-referenced-by-count":7,"title":["What transcranial direct current stimulation intensity is best for cognitive enhancement?"],"prefix":"10.1152","volume":"125","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5656-7987","authenticated-orcid":false,"given":"Jason","family":"Smucny","sequence":"first","affiliation":[{"name":"Department of Psychiatry and Behavioral Sciences, University of California, Davis, California"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"24","reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brs.2016.04.006"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00423.2020"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1111\/ejn.13640"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1038\/s41380-019-0426-0"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2006.11.009"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2012.07.004"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyg.2019.02164"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1038\/s41380-019-0499-9"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2017.09.020"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.3389\/fnhum.2013.00602"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1038\/35086012"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2015.01.033"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2011.06.069"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyg.2020.00585"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-54469-4"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2014.00104"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2017.00147"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2017.03.005"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1016\/j.schres.2014.03.006"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhj091"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1016\/j.brs.2014.02.004"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1016\/j.brs.2014.02.003"}],"container-title":["Journal of Neurophysiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.physiology.org\/doi\/pdf\/10.1152\/jn.00652.2020","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,6,23]],"date-time":"2021-06-23T08:45:05Z","timestamp":1624437905000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.physiology.org\/doi\/10.1152\/jn.00652.2020"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2,1]]},"references-count":22,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,2,1]]}},"alternative-id":["10.1152\/jn.00652.2020"],"URL":"https:\/\/doi.org\/10.1152\/jn.00652.2020","relation":{},"ISSN":["0022-3077","1522-1598"],"issn-type":[{"value":"0022-3077","type":"print"},{"value":"1522-1598","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,2,1]]},"assertion":[{"value":"2020-11-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-12-30","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-01-01","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-02-25","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}