{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T04:39:39Z","timestamp":1790224779393,"version":"4.1.0"},"reference-count":81,"publisher":"American Physiological Society","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Neurophysiology"],"published-print":{"date-parts":[[2013,9,15]]},"abstract":"<jats:p>A module is a functional unit of the nervous system that specifies functionally relevant patterns of muscle activation. In adults, four to five modules account for muscle activation during walking. Neurological injury alters modular control and is associated with walking impairments. The effect of neurological injury on modular control in children is unknown and may differ from adults due to their immature and developing nervous systems. We examined modular control of locomotor tasks in children with incomplete spinal cord injuries (ISCIs) and control children. Five controls (8.6 \u00b1 2.7 yr of age) and five children with ISCIs (8.6 \u00b1 3.7 yr of age performed treadmill walking, overground walking, pedaling, supine lower extremity flexion\/extension, stair climbing, and crawling. Electromyograms (EMGs) were recorded in bilateral leg muscles. Nonnegative matrix factorization was applied, and the minimum number of modules required to achieve 90% of the \u201cvariance accounted for\u201d (VAF) was calculated. On average, 3.5 modules explained muscle activation in the controls, whereas 2.4 modules were required in the children with ISCIs. To determine if control is similar across tasks, the module weightings identified from treadmill walking were used to reconstruct the EMGs from each of the other tasks. This resulted in VAF values exceeding 86% for each child and each locomotor task. Our results suggest that 1) modularity is constrained in children with ISCIs and 2) for each child, similar neural control mechanisms are used across locomotor tasks. These findings suggest that interventions that activate the neuromuscular system to enhance walking also may influence the control of other locomotor tasks.<\/jats:p>","DOI":"10.1152\/jn.00676.2012","type":"journal-article","created":{"date-parts":[[2013,6,13]],"date-time":"2013-06-13T03:14:30Z","timestamp":1371093270000},"page":"1415-1425","source":"Crossref","is-referenced-by-count":57,"title":["Modular control of varied locomotor tasks in children with incomplete spinal cord injuries"],"prefix":"10.1152","volume":"110","author":[{"given":"Emily J.","family":"Fox","sequence":"first","affiliation":[{"name":"Department of Physical Therapy, University of Florida, Gainesville, Florida;"},{"name":"Brooks Rehabilitation Clinical Research Center, Brooks Rehabilitation, Jacksonville, Florida;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole J.","family":"Tester","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy, University of Florida, 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