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Stimulus-evoked reflectance changes at 690 nm were observed in 9\/10 cats but lacked stimulus-dependent topography. In two experiments, stimulus-evoked optical signals at 540 nm were compared with multiunit responses to the same stimuli recorded at multiple sites. A significant correlation ( P &lt; 0.05) between magnitude of reflectance decrease and multiunit response strength was evident in only one of five stimulus conditions in each experiment. There was no significant correlation when data were pooled across all stimulus conditions in either experiment. In one experiment, the spatial distribution of activated patches, evident in records of spontaneous activity at 540 nm, was similar to that of patches activated by tonal stimuli. These results suggest that local cerebral blood volume changes reflect the gross tonotopic organization of A1 but are not restricted to the sites of spiking neurons. <\/jats:p>","DOI":"10.1152\/jn.2001.85.3.1283","type":"journal-article","created":{"date-parts":[[2017,12,21]],"date-time":"2017-12-21T05:14:09Z","timestamp":1513833249000},"page":"1283-1298","source":"Crossref","is-referenced-by-count":39,"title":["Spontaneous and Stimulus-Evoked Intrinsic Optical Signals  in Primary Auditory Cortex of the Cat"],"prefix":"10.1152","volume":"85","author":[{"given":"Matthew W.","family":"Spitzer","sequence":"first","affiliation":[{"name":"Vision, Touch and Hearing Research Centre, Department of Physiology and Pharmacology, The University of Queensland, St. Lucia, Queensland 4072, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael B.","family":"Calford","sequence":"additional","affiliation":[{"name":"Vision, Touch and Hearing Research Centre, Department of 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