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GABA\n                    <jats:sub>A<\/jats:sub>\n                    Rs are heteropentameric ligand-gated ion channels that are found concentrated at inhibitory postsynaptic sites where they mediate phasic inhibition and at extrasynaptic sites where they mediate tonic inhibition. The efficacy of inhibition and thus neuronal excitability is critically dependent on the accumulation of specific GABA\n                    <jats:sub>A<\/jats:sub>\n                    R subtypes at inhibitory synapses. Here we evaluate how neurons control the number of GABA\n                    <jats:sub>A<\/jats:sub>\n                    Rs on the neuronal plasma membrane together with their selective stabilization at synaptic sites. We then go on to examine the impact that these processes have on the strength of synaptic inhibition and behavior.\n                  <\/jats:p>","DOI":"10.1152\/physrev.00015.2010","type":"journal-article","created":{"date-parts":[[2011,7,8]],"date-time":"2011-07-08T16:06:10Z","timestamp":1310141170000},"page":"1009-1022","source":"Crossref","is-referenced-by-count":192,"title":["The Dynamic Modulation of GABA\n                    <sub>A<\/sub>\n                    Receptor Trafficking and Its Role in Regulating the Plasticity of Inhibitory Synapses"],"prefix":"10.1152","volume":"91","author":[{"given":"Mansi","family":"Vithlani","sequence":"first","affiliation":[{"name":"Department of Neuroscience, Tufts University School of Medicine, Boston, Massachusetts; and Department of Neuroscience, Physiology, and Pharmacology, University College London, London, United 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