{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T07:07:33Z","timestamp":1791270453304,"version":"4.1.0"},"reference-count":768,"publisher":"American Physiological Society","issue":"4","funder":[{"DOI":"10.13039\/100000897","name":"Cystic Fibrosis Foundation (CFF)","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000897","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006501","name":"Cystic Fibrosis Foundation Therapeutics (Cystic Fibrosis Foundation Therapeutics, Inc.)","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006501","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Physiological Reviews"],"published-print":{"date-parts":[[2015,10]]},"abstract":"<jats:p>Submucosal glands contribute to airway surface liquid (ASL), a film that protects all airway surfaces. Glandular mucus comprises electrolytes, water, the gel-forming mucin MUC5B, and hundreds of different proteins with diverse protective functions. Gland volume per unit area of mucosal surface correlates positively with impaction rate of inhaled particles. In human main bronchi, the volume of the glands is \u223c50 times that of surface goblet cells, but the glands diminish in size and frequency distally. ASL and its trapped particles are removed from the airways by mucociliary transport. Airway glands have a tubuloacinar structure, with a single terminal duct, a nonciliated collecting duct, then branching secretory tubules lined with mucous cells and ending in serous acini. They allow for a massive increase in numbers of mucus-producing cells without replacing surface ciliated cells. Active secretion of Cl<jats:sup>\u2212<\/jats:sup>and HCO<jats:sub>3<\/jats:sub><jats:sup>\u2212<\/jats:sup>by serous cells produces most of the fluid of gland secretions. Glands are densely innervated by tonically active, mutually excitatory airway intrinsic neurons. Most gland mucus is secreted constitutively in vivo, with large, transient increases produced by emergency reflex drive from the vagus. Elevations of [cAMP]<jats:sub>i<\/jats:sub>and [Ca<jats:sup>2+<\/jats:sup>]<jats:sub>i<\/jats:sub>coordinate electrolyte and macromolecular secretion and probably occur together for baseline activity in vivo, with cholinergic elevation of [Ca<jats:sup>2+<\/jats:sup>]<jats:sub>i<\/jats:sub>being mainly responsive for transient increases in secretion. Altered submucosal gland function contributes to the pathology of all obstructive diseases, but is an early stage of pathogenesis only in cystic fibrosis.<\/jats:p>","DOI":"10.1152\/physrev.00039.2014","type":"journal-article","created":{"date-parts":[[2015,9,3]],"date-time":"2015-09-03T01:43:45Z","timestamp":1441244625000},"page":"1241-1319","source":"Crossref","is-referenced-by-count":205,"title":["Airway Gland Structure and Function"],"prefix":"10.1152","volume":"95","author":[{"given":"Jonathan H.","family":"Widdicombe","sequence":"first","affiliation":[{"name":"Department of Physiology and Membrane Biology, University of California-Davis, Davis, California; and Department of Psychology and Cystic Fibrosis Research Laboratory, Stanford University, Stanford, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey J.","family":"Wine","sequence":"additional","affiliation":[{"name":"Department of Physiology and Membrane Biology, University of California-Davis, Davis, California; and Department of Psychology and Cystic Fibrosis Research Laboratory, Stanford University, Stanford, California"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"24","reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-61779-513-8_16"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00648.2010"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.00055.2004"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1422091112"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1002\/jemt.1070230108"},{"key":"B6","first-page":"29","volume":"132","author":"Adams DR","year":"1981","journal-title":"J Anat"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1165\/ajrcmb\/6.5.550"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.3109\/01902148709064307"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00630.2006"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1378\/chest.101.4.916"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm\/140.2.477"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.165.10.5760"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1990.sp018042"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1136\/thx.30.6.687"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1085\/jgp.201110718"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1093\/glycob\/5.8.733"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9681(58)90185-1"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.88.14.6003"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1385\/CRIAI:27:1:035"},{"key":"B20","first-page":"277","volume":"347","author":"Argueso P","year":"2006","journal-title":"Methods Mol Biol"},{"key":"B21","first-page":"199","volume":"19","author":"Aspin N","year":"1976","journal-title":"Mod Probl Paediatr"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1177\/41.10.8245407"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.2500\/105065897781446685"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1016\/j.yexcr.2005.06.010"},{"key":"B25","first-page":"811","volume":"115","author":"Baker AP","year":"1977","journal-title":"Am Rev Respir Dis"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1985.sp015773"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3940(83)90236-7"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1002\/cne.902460408"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.1995.268.3.L526"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.1999.277.4.L694"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.00159.2005"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.00277.2001"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1172\/JCI2410"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.95.16.9541"},{"key":"B35","first-page":"107","volume":"104","author":"Bang BG","year":"1959","journal-title":"Bull Johns Hopkins Hosp"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.00058.2012"},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.160.2.9805081"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.1165\/ajrcmb\/3.2.165"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.1991.261.4.L223"},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.1990.258.2.L81"},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.1172\/JCI114577"},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm\/141.3.706"},{"key":"B43","doi-asserted-by":"publisher","DOI":"10.1165\/ajrcmb\/4.3.228"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.1172\/JCI114780"},{"key":"B45","first-page":"47","volume":"44","author":"Baraniuk JN","year":"1996","journal-title":"J Invest Med"},{"key":"B46","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.1992.262.1.L48"},{"key":"B47","doi-asserted-by":"publisher","DOI":"10.3109\/01902148309061513"},{"key":"B48","doi-asserted-by":"publisher","DOI":"10.1007\/BF01965397"},{"key":"B49","doi-asserted-by":"publisher","DOI":"10.1159\/000136349"},{"key":"B50","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.04-02-00508.1984"},{"key":"B51","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.ph.52.030190.000525"},{"key":"B52","doi-asserted-by":"publisher","DOI":"10.1007\/BF00216752"},{"key":"B53","doi-asserted-by":"publisher","DOI":"10.1002\/path.1711190107"},{"key":"B54","first-page":"404","volume":"57","author":"Baskerville A","year":"1976","journal-title":"Br J Exp Pathol"},{"key":"B55","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.0803022"},{"key":"B56","doi-asserted-by":"publisher","DOI":"10.1016\/S0046-8177(76)80023-8"},{"key":"B57","doi-asserted-by":"publisher","DOI":"10.1159\/000086651"},{"key":"B58","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0039888"},{"key":"B59","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2222.2011.03814.x"},{"key":"B60","doi-asserted-by":"publisher","DOI":"10.1085\/jgp.200810097"},{"key":"B61","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2013.261909"},{"key":"B62","doi-asserted-by":"publisher","DOI":"10.1016\/j.it.2003.11.007"},{"key":"B63","doi-asserted-by":"publisher","DOI":"10.1007\/s00418-010-0683-0"},{"key":"B64","doi-asserted-by":"publisher","DOI":"10.1002\/path.1726"},{"key":"B65","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201404-0670OC"},{"key":"B66","doi-asserted-by":"publisher","DOI":"10.1126\/science.177.4051.804"},{"key":"B67","first-page":"S30","volume":"1","author":"Bloom SR","year":"1985","journal-title":"Pediatr Pulmonol"},{"key":"B68","volume-title":"A Textbook of Histology","author":"Bloom W","year":"1968"},{"key":"B69","first-page":"217","volume-title":"Airway Secretion","author":"Boat TF","year":"1994"},{"key":"B70","doi-asserted-by":"publisher","DOI":"10.1378\/chest.67.2_Supplement.32S"},{"key":"B71","doi-asserted-by":"publisher","DOI":"10.1177\/000348946507400207"},{"key":"B72","first-page":"321","volume":"101","author":"Bojsen-Moller F","year":"1967","journal-title":"J Anat"},{"key":"B73","doi-asserted-by":"publisher","DOI":"10.1002\/ar.1091500103"},{"key":"B74","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1984.57.2.457"},{"key":"B75","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1980.49.6.1027"},{"key":"B76","doi-asserted-by":"publisher","DOI":"10.3109\/01902148709068812"},{"key":"B77","doi-asserted-by":"publisher","DOI":"10.1165\/ajrcmb.20.6.3475"},{"key":"B78","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1981.51.3.706"},{"key":"B79","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.95103s6229"},{"key":"B80","doi-asserted-by":"publisher","DOI":"10.1136\/thx.36.2.108"},{"key":"B81","doi-asserted-by":"publisher","DOI":"10.1136\/thx.32.2.163"},{"key":"B82","doi-asserted-by":"publisher","DOI":"10.1164\/arrd.1984.129.5.823"},{"key":"B83","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a015016"},{"key":"B84","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1972.32.2.160"},{"key":"B85","doi-asserted-by":"publisher","DOI":"10.1136\/thx.30.1.72"},{"key":"B86","doi-asserted-by":"publisher","DOI":"10.1007\/BF02593654"},{"key":"B87","doi-asserted-by":"publisher","DOI":"10.1165\/ajrcmb.20.2.3259"},{"key":"B88","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.1995.269.2.C511"},{"key":"B89","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2006.062190"},{"key":"B90","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00023.2002"},{"key":"B91","first-page":"2434","volume":"36","author":"Burnstock G","year":"1977","journal-title":"Federation Proc"},{"key":"B92","doi-asserted-by":"publisher","DOI":"10.1126\/science.1223012"},{"key":"B93","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1896.sp000618"},{"key":"B94","doi-asserted-by":"publisher","DOI":"10.1080\/00039896.1974.10666572"},{"key":"B95","doi-asserted-by":"publisher","DOI":"10.1165\/rcmb.2003-0142OC"},{"key":"B96","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.00085.2006"},{"key":"B97","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.1997.272.4.L731"},{"key":"B98","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.00347.2005"},{"key":"B99","doi-asserted-by":"publisher","DOI":"10.1126\/science.1163518"},{"key":"B100","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2559.2009.03377.x"},{"key":"B101","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm\/147.2.405"},{"key":"B102","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.02.00275802"},{"key":"B103","doi-asserted-by":"publisher","DOI":"10.1016\/0014-2999(87)90294-9"},{"key":"B104","first-page":"5541","volume":"132","author":"Carstairs R","year":"1985","journal-title":"Am Rev Repir Dis"},{"key":"B105","first-page":"69","volume":"108","author":"Chakrin LW","year":"1973","journal-title":"Am Rev Respir Dis"},{"key":"B106","doi-asserted-by":"publisher","DOI":"10.1007\/BF00168025"},{"key":"B107","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.00180.2010"},{"key":"B108","doi-asserted-by":"publisher","DOI":"10.1081\/JAS-200026405"},{"key":"B109","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2010.11.029"},{"key":"B110","doi-asserted-by":"publisher","DOI":"10.1165\/rcmb.2003-0103OC"},{"key":"B111","doi-asserted-by":"publisher","DOI":"10.1016\/0003-2697(81)90782-X"},{"key":"B112","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M411703200"},{"key":"B113","doi-asserted-by":"publisher","DOI":"10.1136\/thx.40.12.889"},{"key":"B114","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0024424"},{"key":"B115","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.00049.2010"},{"key":"B116","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2011.11.024"},{"key":"B117","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-7580.2000.19730361.x"},{"key":"B118","doi-asserted-by":"publisher","DOI":"10.1172\/JCI31992"},{"key":"B119","doi-asserted-by":"publisher","DOI":"10.1172\/JCI37284"},{"key":"B120","doi-asserted-by":"publisher","DOI":"10.1007\/BF02631327"},{"key":"B121","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.1041300202"},{"key":"B122","doi-asserted-by":"publisher","DOI":"10.2174\/156801005774912806"},{"key":"B123","doi-asserted-by":"publisher","DOI":"10.1201\/b14423-14"},{"key":"B124","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.42.10.1026"},{"key":"B125","doi-asserted-by":"crossref","first-page":"3267","DOI":"10.1128\/IAI.67.7.3267-3275.1999","volume":"67","author":"Cole AM","year":"1999","journal-title":"Infect Immun"},{"key":"B126","first-page":"531","volume":"124","author":"Coles SJ","year":"1981","journal-title":"Am Rev Respir Dis"},{"key":"B127","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1984.57.5.1323"},{"key":"B128","first-page":"40","volume":"109","author":"Coles SJ","year":"1984","journal-title":"Ciba Found Symp"},{"key":"B129","doi-asserted-by":"publisher","DOI":"10.1016\/0090-6980(83)90101-6"},{"key":"B130","doi-asserted-by":"publisher","DOI":"10.1016\/j.febslet.2006.12.025"},{"key":"B131","doi-asserted-by":"publisher","DOI":"10.1007\/BF01869469"},{"key":"B132","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.00143.2012"},{"key":"B133","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.00454.2006"},{"key":"B134","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00059009"},{"key":"B135","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1984.56.4.1076"},{"key":"B136","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2001.013300"},{"key":"B137","doi-asserted-by":"publisher","DOI":"10.1016\/j.pupt.2006.03.013"},{"key":"B138","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.89.11.5171"},{"key":"B139","doi-asserted-by":"publisher","DOI":"10.1203\/01.PDR.0000049510.15555.30"},{"key":"B140","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1986.61.4.1375"},{"key":"B141","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.1990.259.4.L198"},{"key":"B142","doi-asserted-by":"publisher","DOI":"10.1111\/j.1476-5381.2010.01058.x"},{"key":"B143","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2010.05879.x"},{"key":"B144","doi-asserted-by":"publisher","DOI":"10.1159\/000087235"},{"key":"B145","doi-asserted-by":"publisher","DOI":"10.1165\/rcmb.2005-0059OC"},{"key":"B146","doi-asserted-by":"publisher","DOI":"10.1369\/jhc.2009.954891"},{"key":"B147","doi-asserted-by":"publisher","DOI":"10.1016\/j.biocel.2007.05.013"},{"key":"B148","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1982.52.6.1416"},{"key":"B149","first-page":"547","volume":"120","author":"Davis B","year":"1979","journal-title":"Am Rev Respir Dis"},{"key":"B150","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.8035121"},{"key":"B151","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1982.53.4.985"},{"key":"B152","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1991.71.3.939"},{"key":"B153","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.physiol.70.113006.100638"},{"key":"B154","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9969(80)90030-8"},{"key":"B155","first-page":"549","volume":"22","author":"De Haller R","year":"1965","journal-title":"Med Thorac"},{"key":"B156","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00141611"},{"key":"B157","first-page":"882","volume":"133","author":"De Water R","year":"1986","journal-title":"Am Rev Respir Dis"},{"key":"B158","doi-asserted-by":"publisher","DOI":"10.1152\/physiolgenomics.2001.4.3.165"},{"key":"B159","doi-asserted-by":"publisher","DOI":"10.1021\/pr700764j"},{"key":"B160","doi-asserted-by":"publisher","DOI":"10.1096\/fj.10-179549"},{"key":"B161","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.1999.276.4.C827"},{"key":"B162","doi-asserted-by":"publisher","DOI":"10.1085\/jgp.113.5.743"},{"key":"B163","doi-asserted-by":"publisher","DOI":"10.1002\/cne.903040213"},{"key":"B164","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0185(19990201)254:2<166::AID-AR2>3.0.CO;2-E"},{"key":"B165","doi-asserted-by":"publisher","DOI":"10.1007\/BF00210505"},{"key":"B166","doi-asserted-by":"publisher","DOI":"10.1007\/BF01869084"},{"key":"B167","doi-asserted-by":"publisher","DOI":"10.1136\/thx.35.3.198"},{"key":"B168","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2007.082388"},{"key":"B169","doi-asserted-by":"publisher","DOI":"10.1016\/j.ydbio.2007.01.038"},{"key":"B170","doi-asserted-by":"crossref","first-page":"4441","DOI":"10.1242\/dev.126.20.4441","volume":"126","author":"Duan D","year":"1999","journal-title":"Development"},{"key":"B171","doi-asserted-by":"publisher","DOI":"10.1378\/chest.07-2934"},{"key":"B172","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.00326.2003"},{"key":"B173","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.13.1.27"},{"key":"B174","doi-asserted-by":"publisher","DOI":"10.1136\/thx.24.2.176"},{"key":"B175","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.1997.272.6.L1121"},{"key":"B176","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.1992.262.4.L418"},{"key":"B177","doi-asserted-by":"publisher","DOI":"10.1038\/ng1192-240"},{"key":"B178","doi-asserted-by":"publisher","DOI":"10.1172\/JCI116155"},{"key":"B179","doi-asserted-by":"publisher","DOI":"10.1016\/j.pbiomolbio.2009.10.002"},{"key":"B180","doi-asserted-by":"publisher","DOI":"10.1513\/pats.200808-087RM"},{"key":"B181","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra0910061"},{"key":"B182","doi-asserted-by":"publisher","DOI":"10.1016\/S0091-6749(95)70128-1"},{"key":"B183","first-page":"238","volume":"37","author":"Farber S","year":"1944","journal-title":"Arch Pathol"},{"key":"B184","first-page":"415","volume-title":"The Lung Scientific Foundations","author":"Finkbeiner WE","year":"1997"},{"key":"B185","first-page":"561","volume":"22","author":"Finkbeiner WE","year":"1986","journal-title":"In Vitro"},{"key":"B186","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.1994.267.2.L206"},{"key":"B187","doi-asserted-by":"publisher","DOI":"10.1007\/s11626-009-9262-x"},{"key":"B188","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.00210.2010"},{"key":"B189","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.00032.2007"},{"key":"B190","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.00421.2009"},{"key":"B191","doi-asserted-by":"publisher","DOI":"10.1007\/s00232-006-0861-0"},{"key":"B192","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.00369.2001"},{"key":"B193","first-page":"269","volume":"13","author":"Florey H","year":"1932","journal-title":"Br J Exp Pathol"},{"key":"B194","doi-asserted-by":"publisher","DOI":"10.1172\/JCI118463"},{"key":"B195","doi-asserted-by":"publisher","DOI":"10.1096\/fj.01-0036com"},{"key":"B196","doi-asserted-by":"publisher","DOI":"10.1152\/ajprenal.1979.236.1.F1"},{"key":"B197","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1101\/cshperspect.a009563","volume":"2","author":"Frizzell RA","year":"2012","journal-title":"Cold Spring Harb Perspect Med"},{"key":"B198","doi-asserted-by":"publisher","DOI":"10.1165\/ajrcmb.12.3.7873196"},{"key":"B199","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1992.73.2.625"},{"key":"B200","doi-asserted-by":"publisher","DOI":"10.1177\/0192623310378867"},{"key":"B201","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.1996.271.4.L593"},{"key":"B202","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.2000.278.1.L177"},{"key":"B203","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0009098"},{"key":"B204","doi-asserted-by":"publisher","DOI":"10.1016\/0167-4889(86)90142-4"},{"key":"B205","doi-asserted-by":"publisher","DOI":"10.1098\/rspb.1975.0151"},{"key":"B206","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4613-4172-7_7"},{"key":"B207","doi-asserted-by":"publisher","DOI":"10.1172\/JCI38662"},{"key":"B208","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M111.266734"},{"key":"B209","doi-asserted-by":"publisher","DOI":"10.1177\/00220345870660020201"},{"key":"B210","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.1986.251.2.C223"},{"key":"B211","doi-asserted-by":"publisher","DOI":"10.3109\/01902148709064311"},{"key":"B212","doi-asserted-by":"publisher","DOI":"10.1016\/0040-8166(89)90021-9"},{"key":"B213","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.ph.57.030195.003135"},{"key":"B214","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1982.52.5.1153"},{"key":"B215","first-page":"413","volume":"122","author":"German VF","year":"1980","journal-title":"Am Rev Respir Dis"},{"key":"B216","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1979.47.4.867"},{"key":"B217","doi-asserted-by":"publisher","DOI":"10.1165\/ajrcmb.22.6.3980"},{"key":"B218","doi-asserted-by":"publisher","DOI":"10.1007\/BF00218896"},{"key":"B219","doi-asserted-by":"publisher","DOI":"10.1002\/jemt.1070230203"},{"key":"B220","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.cellbio.19.031403.160043"},{"key":"B221","doi-asserted-by":"publisher","DOI":"10.1136\/thx.42.6.431"},{"key":"B222","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.86.19.7634"},{"key":"B223","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200304-505SO"},{"key":"B224","doi-asserted-by":"publisher","DOI":"10.1177\/39.2.1987263"},{"key":"B225","doi-asserted-by":"publisher","DOI":"10.1136\/thx.15.2.142"},{"key":"B226","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1963.tb16665.x"},{"key":"B227","doi-asserted-by":"publisher","DOI":"10.1016\/S1097-2765(02)00708-6"},{"key":"B228","first-page":"115","volume":"123","author":"Goodman MR","year":"1981","journal-title":"Am Rev Respir Dis"},{"key":"B229","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm\/141.1.72"},{"key":"B230","doi-asserted-by":"publisher","DOI":"10.1016\/0091-6749(89)90301-1"},{"key":"B231","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2008.111435"},{"key":"B232","doi-asserted-by":"publisher","DOI":"10.1046\/j.1475-0961.2003.00519.x"},{"key":"B233","doi-asserted-by":"publisher","DOI":"10.1053\/rmed.2001.1221"},{"key":"B234","doi-asserted-by":"publisher","DOI":"10.1038\/labinvest.3780283"},{"key":"B235","doi-asserted-by":"publisher","DOI":"10.1378\/chest.96.5.984"},{"key":"B236","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.1994.267.1.C293"},{"key":"B237","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcf.2004.05.040"},{"key":"B238","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.1997.272.3.C1058"},{"key":"B239","doi-asserted-by":"publisher","DOI":"10.1165\/rcmb.2006-0184TR"},{"key":"B240","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2002.030148"},{"key":"B241","first-page":"277","volume":"69","author":"Hahn HL","year":"1986","journal-title":"Eur J Appl Pathol Dis"},{"key":"B242","doi-asserted-by":"publisher","DOI":"10.1002\/ar.22783"},{"key":"B243","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.1992.262.3.L257"},{"key":"B244","doi-asserted-by":"publisher","DOI":"10.1042\/bst0080072"},{"key":"B245","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200704-565OC"},{"key":"B246","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.1995.269.4.C929"},{"key":"B247","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(89)90635-5"},{"key":"B248","doi-asserted-by":"publisher","DOI":"10.1016\/j.mib.2011.11.002"},{"key":"B249","doi-asserted-by":"publisher","DOI":"10.1080\/01926230600713475"},{"key":"B250","first-page":"3","volume-title":"The Airway Epithelium: Physiology, Pathology, and Pharmacology","author":"Harkema JR","year":"1991"},{"key":"B251","doi-asserted-by":"publisher","DOI":"10.3109\/01902148409087895"},{"key":"B252","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.physiol.70.113006.100659"},{"key":"B253","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.1994.266.5.L502"},{"key":"B254","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1991.71.5.1669"},{"key":"B255","doi-asserted-by":"publisher","DOI":"10.1016\/0034-5687(90)90097-I"},{"key":"B256","doi-asserted-by":"publisher","DOI":"10.1016\/0034-5687(91)90110-5"},{"key":"B257","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1991.71.5.1663"},{"key":"B258","doi-asserted-by":"publisher","DOI":"10.1007\/s00005-011-0113-6"},{"key":"B259","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200603-310OC"},{"key":"B260","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1993.75.6.2347"},{"key":"B261","first-page":"415","volume":"63","author":"Helal R","year":"2008","journal-title":"Pharmazie"},{"key":"B262","doi-asserted-by":"publisher","DOI":"10.1172\/JCI73469"},{"key":"B263","doi-asserted-by":"publisher","DOI":"10.1016\/0021-8502(86)90035-2"},{"key":"B264","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuint.2007.06.023"},{"key":"B265","doi-asserted-by":"publisher","DOI":"10.1016\/0248-4900(90)90314-S"},{"key":"B266","doi-asserted-by":"publisher","DOI":"10.1177\/00034894991080S702"},{"key":"B267","doi-asserted-by":"publisher","DOI":"10.3109\/00016488209130861"},{"key":"B268","doi-asserted-by":"publisher","DOI":"10.3109\/00016488509108597"},{"key":"B269","doi-asserted-by":"publisher","DOI":"10.1177\/000348949610500711"},{"key":"B270","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-0115(96)00093-6"},{"key":"B271","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1323633111"},{"key":"B272","doi-asserted-by":"publisher","DOI":"10.1126\/science.1255825"},{"key":"B273","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(92)91437-9"},{"key":"B274","doi-asserted-by":"publisher","DOI":"10.1007\/BF00492353"},{"key":"B275","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1214596109"},{"key":"B276","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2249.2001.01456.x"},{"key":"B277","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1922.00110120002001"},{"key":"B278","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2006.123653"},{"key":"B279","doi-asserted-by":"publisher","DOI":"10.1007\/s00424-008-0527-0"},{"key":"B280","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.1995.268.3.L361"},{"key":"B281","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.1041630123"},{"key":"B282","doi-asserted-by":"publisher","DOI":"10.1007\/BF00233950"},{"key":"B283","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200510043"},{"key":"B284","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm\/139.5.1139"},{"key":"B285","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.1998.274.5.L762"},{"key":"B286","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.1997.272.2.L372"},{"key":"B287","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.1997.272.2.L203"},{"key":"B288","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200807-1056OC"},{"key":"B289","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1843.2007.01195.x"},{"key":"B290","doi-asserted-by":"publisher","DOI":"10.1016\/S0034-5288(18)31852-6"},{"key":"B291","doi-asserted-by":"publisher","DOI":"10.1002\/path.1711060204"},{"key":"B292","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.00124.2004"},{"key":"B293","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.1990.259.6.L345"},{"key":"B294","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.1992.262.2.L223"},{"key":"B295","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1106695108"},{"key":"B296","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-291X(88)80574-6"},{"key":"B297","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1183\/09031936.93.06020169","volume":"6","author":"Jacquot J","year":"1993","journal-title":"Eur Respir J"},{"key":"B298","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.1041610303"},{"key":"B299","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.186.6.568"},{"key":"B300","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.131087598"},{"key":"B301","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.00009.2014"},{"key":"B302","doi-asserted-by":"publisher","DOI":"10.1126\/science.8211164"},{"key":"B303","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7793.1997.637bm.x"},{"key":"B304","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-011-0822-3"},{"key":"B305","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-61779-513-8_6"},{"key":"B306","doi-asserted-by":"publisher","DOI":"10.1016\/0192-0561(83)90013-9"},{"key":"B307","doi-asserted-by":"publisher","DOI":"10.1007\/BF01994273"},{"key":"B308","first-page":"917","volume":"131","author":"Johnson HG","year":"1985","journal-title":"Am Rev Respir Dis"},{"key":"B309","doi-asserted-by":"publisher","DOI":"10.1172\/JCI43466"},{"key":"B310","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0116756"},{"key":"B311","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M512766200"},{"key":"B312","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M208826200"},{"key":"B313","first-page":"280","volume":"2","author":"Joo NS","year":"2001","journal-title":"J Physiol"},{"key":"B314","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M407077200"},{"key":"B315","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M202712200"},{"key":"B316","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.90636.2008"},{"key":"B317","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.2001.281.2.L458"},{"key":"B318","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1211594110"},{"key":"B319","doi-asserted-by":"publisher","DOI":"10.1085\/jgp.200910355"},{"key":"B320","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.164.10.2106073"},{"key":"B321","doi-asserted-by":"publisher","DOI":"10.1016\/S1081-1206(10)61503-7"},{"key":"B322","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.1993.265.2.L200"},{"key":"B323","doi-asserted-by":"publisher","DOI":"10.1016\/S0925-4439(98)00084-2"},{"key":"B324","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199907153410304"},{"key":"B325","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5320(74)90068-9"},{"key":"B326","doi-asserted-by":"publisher","DOI":"10.1038\/mi.2012.81"},{"key":"B327","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.00194.2009"},{"key":"B328","doi-asserted-by":"publisher","DOI":"10.1096\/fj.08-119131"},{"key":"B329","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2010.09.064"},{"key":"B330","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.00372.2010"},{"key":"B331","first-page":"449","volume":"98","author":"Kilburn KH","year":"1968","journal-title":"Am Rev Respir Dis"},{"key":"B332","doi-asserted-by":"publisher","DOI":"10.1080\/00016480600606749"},{"key":"B333","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1996.81.5.2203"},{"key":"B334","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.00156.2006"},{"key":"B335","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.01264.2005"},{"key":"B336","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.97.10112644"},{"key":"B337","first-page":"433","volume-title":"Airway Secretion","author":"Kim KC","year":"1994"},{"key":"B338","doi-asserted-by":"publisher","DOI":"10.1378\/chest.10-2948"},{"key":"B339","doi-asserted-by":"publisher","DOI":"10.1016\/j.prrv.2006.04.199"},{"key":"B340","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200803-391OC"},{"key":"B341","doi-asserted-by":"publisher","DOI":"10.1016\/S0194-5998(97)70018-4"},{"key":"B342","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1099-0496(199903)27:3<174::AID-PPUL4>3.0.CO;2-A"},{"key":"B343","doi-asserted-by":"publisher","DOI":"10.1016\/S0034-5687(01)00214-6"},{"key":"B344","doi-asserted-by":"publisher","DOI":"10.1378\/chest.124.1.306"},{"key":"B345","doi-asserted-by":"publisher","DOI":"10.1172\/JCI0215217"},{"key":"B346","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1984.56.4.868"},{"key":"B347","doi-asserted-by":"publisher","DOI":"10.1038\/ncb1115"},{"key":"B348","doi-asserted-by":"crossref","first-page":"397","DOI":"10.4193\/Rhino11.051","volume":"49","author":"Koblizek V","year":"2011","journal-title":"Rhinology"},{"key":"B349","doi-asserted-by":"publisher","DOI":"10.1007\/BF01789555"},{"key":"B350","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-8707(30)90102-5"},{"key":"B351","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.95.11.6526"},{"key":"B352","first-page":"55","volume":"138","author":"Kratzing JE","year":"1984","journal-title":"J Anat"},{"key":"B353","first-page":"553","volume":"139","author":"Kratzing JE","year":"1984","journal-title":"J Anat"},{"key":"B354","first-page":"135","volume":"157","author":"Kratzing JE","year":"1988","journal-title":"J Anat"},{"key":"B355","doi-asserted-by":"publisher","DOI":"10.1159\/000144426"},{"key":"B356","doi-asserted-by":"publisher","DOI":"10.1165\/ajrcmb.24.3.4367"},{"key":"B357","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.E04-11-1010"},{"key":"B358","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2007.139840"},{"key":"B359","doi-asserted-by":"publisher","DOI":"10.1046\/j.1439-0264.2000.00244.x"},{"key":"B360","first-page":"167","volume":"16","author":"Kunzelmann K","year":"2001","journal-title":"News Physiol Sci"},{"key":"B361","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9343(03)00241-9"},{"key":"B362","first-page":"14","volume":"70","author":"Kyle H","year":"1987","journal-title":"Eur J Respir Dis"},{"key":"B363","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetimm.2009.01.001"},{"key":"B364","doi-asserted-by":"publisher","DOI":"10.1007\/BF00494059"},{"key":"B365","doi-asserted-by":"publisher","DOI":"10.1016\/0007-0971(72)90042-3"},{"key":"B366","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1993.74.6.2771"},{"key":"B367","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.1992.263.2.L232"},{"key":"B368","first-page":"153","volume":"306","author":"Laube DM","year":"2006","journal-title":"Curr Top Microbiol Immunol"},{"key":"B369","doi-asserted-by":"crossref","first-page":"107","DOI":"10.4193\/Rhino10.036","volume":"49","author":"Laudien M","year":"2011","journal-title":"Rhinology"},{"key":"B370","doi-asserted-by":"publisher","DOI":"10.1016\/j.coph.2009.02.004"},{"key":"B371","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M003255200"},{"key":"B372","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.1986.251.1.C115"},{"key":"B373","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1000387"},{"key":"B374","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.1999.277.1.L204"},{"key":"B375","doi-asserted-by":"publisher","DOI":"10.1001\/archoto.2009.97"},{"key":"B376","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0043188"},{"key":"B377","doi-asserted-by":"publisher","DOI":"10.1007\/s12275-014-4512-3"},{"key":"B378","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00011.2011"},{"key":"B379","doi-asserted-by":"publisher","DOI":"10.1172\/JCI42992"},{"key":"B380","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.00342.2009"},{"key":"B381","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M112.412817"},{"key":"B382","doi-asserted-by":"publisher","DOI":"10.1085\/jgp.200810017"},{"key":"B383","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2007.131995"},{"key":"B384","doi-asserted-by":"publisher","DOI":"10.3109\/01902148609061490"},{"key":"B385","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1984.56.2.426"},{"key":"B386","doi-asserted-by":"publisher","DOI":"10.1165\/rcmb.2012-0419RC"},{"key":"B387","doi-asserted-by":"publisher","DOI":"10.1165\/ajrcmb\/9.3.315"},{"key":"B388","doi-asserted-by":"publisher","DOI":"10.1177\/0022034509337114"},{"key":"B389","doi-asserted-by":"publisher","DOI":"10.1001\/jama.293.5.581"},{"key":"B390","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.1983.244.5.C391"},{"key":"B391","doi-asserted-by":"publisher","DOI":"10.1165\/ajrcmb\/1.1.41"},{"key":"B392","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.1998.275.1.C323"},{"key":"B393","doi-asserted-by":"publisher","DOI":"10.1042\/bj1750565"},{"key":"B394","doi-asserted-by":"publisher","DOI":"10.1165\/rcmb.2013-0499MA"},{"key":"B395","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjp.0702942"},{"key":"B396","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjp.0702288"},{"key":"B397","doi-asserted-by":"publisher","DOI":"10.1152\/physiolgenomics.00185.2011"},{"key":"B398","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00051512"},{"key":"B399","doi-asserted-by":"publisher","DOI":"10.1165\/ajrcmb\/5.1.71"},{"key":"B400","doi-asserted-by":"publisher","DOI":"10.1124\/jpet.110.171561"},{"key":"B401","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1406414111"},{"key":"B402","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1934.03600040074006"},{"key":"B403","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.156.6.96-10088"},{"key":"B404","first-page":"1089","volume":"11","author":"Luchtel VL","year":"1978","journal-title":"Scanning Electron Microsc"},{"key":"B405","doi-asserted-by":"publisher","DOI":"10.3109\/01902148709062842"},{"key":"B406","doi-asserted-by":"publisher","DOI":"10.1016\/S0954-6111(05)80333-6"},{"key":"B407","doi-asserted-by":"publisher","DOI":"10.1016\/0091-6749(91)90390-A"},{"key":"B408","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm\/137.2.353"},{"key":"B409","doi-asserted-by":"publisher","DOI":"10.1007\/BF01966296"},{"key":"B410","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.1990.258.2.L68"},{"key":"B411","doi-asserted-by":"publisher","DOI":"10.3109\/01902148909069606"},{"key":"B412","doi-asserted-by":"publisher","DOI":"10.1369\/jhc.6A7100.2007"},{"key":"B413","doi-asserted-by":"publisher","DOI":"10.1186\/1746-6148-9-222"},{"key":"B414","doi-asserted-by":"publisher","DOI":"10.1016\/0014-2999(91)90121-6"},{"key":"B415","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1977.00780230060008"},{"key":"B416","doi-asserted-by":"publisher","DOI":"10.1111\/j.1476-5381.1990.tb14170.x"},{"key":"B417","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M110.185074"},{"key":"B418","first-page":"253","volume":"6","author":"March ME","year":"2013","journal-title":"Int J Gen Med"},{"key":"B419","doi-asserted-by":"publisher","DOI":"10.1002\/ar.1092050304"},{"key":"B420","doi-asserted-by":"crossref","first-page":"1546","DOI":"10.1152\/ajplegacy.1976.231.5.1546","volume":"231","author":"Marin MG","year":"1976","journal-title":"Am J Physiol"},{"key":"B421","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1977.42.5.735"},{"key":"B422","doi-asserted-by":"publisher","DOI":"10.1084\/jem.161.4.657"},{"key":"B423","first-page":"499","volume":"126","author":"Marom Z","year":"1982","journal-title":"Am Rev Respir Dis"},{"key":"B425","doi-asserted-by":"publisher","DOI":"10.1172\/JCI110207"},{"key":"B426","doi-asserted-by":"publisher","DOI":"10.1172\/JCI111674"},{"key":"B427","doi-asserted-by":"publisher","DOI":"10.1084\/jem.159.3.844"},{"key":"B428","doi-asserted-by":"publisher","DOI":"10.1016\/0090-6980(84)90115-1"},{"key":"B429","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.00388.2010"},{"key":"B430","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2222.2006.02451.x"},{"key":"B431","doi-asserted-by":"publisher","DOI":"10.1172\/JCI2687"},{"key":"B432","doi-asserted-by":"publisher","DOI":"10.1165\/ajrcmb.10.6.8003339"},{"key":"B433","doi-asserted-by":"publisher","DOI":"10.1097\/MNH.0b013e3283484b06"},{"key":"B434","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.1993.264.2.L93"},{"key":"B435","doi-asserted-by":"publisher","DOI":"10.1165\/ajrcmb.15.4.8879186"},{"key":"B436","doi-asserted-by":"publisher","DOI":"10.1378\/chest.38.6.616"},{"key":"B437","doi-asserted-by":"publisher","DOI":"10.1038\/nature07005"},{"key":"B438","doi-asserted-by":"publisher","DOI":"10.1126\/science.284.5420.1635"},{"key":"B439","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201004-0643OC"},{"key":"B440","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4613-4172-7_5"},{"key":"B441","first-page":"291","volume":"107","author":"Meyrick B","year":"1970","journal-title":"J Anat"},{"key":"B442","doi-asserted-by":"publisher","DOI":"10.1136\/thx.24.6.729"},{"key":"B443","doi-asserted-by":"publisher","DOI":"10.1136\/thx.48.8.812"},{"key":"B444","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.1981.241.1.C18"},{"key":"B445","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.04.10031504"},{"key":"B446","doi-asserted-by":"publisher","DOI":"10.1136\/thorax.57.2.146"},{"key":"B447","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1989.67.6.2553"},{"key":"B448","doi-asserted-by":"publisher","DOI":"10.1513\/AnnalsATS.201404-166OC"},{"key":"B449","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.1997.273.6.L1208"},{"key":"B450","doi-asserted-by":"publisher","DOI":"10.1177\/30.11.6754808"},{"key":"B451","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(82)90671-0"},{"key":"B452","doi-asserted-by":"publisher","DOI":"10.1007\/s00232-008-9093-9"},{"key":"B453","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2010.187237"},{"key":"B454","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.291.6504.1235"},{"key":"B455","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1992.73.5.2069"},{"key":"B456","doi-asserted-by":"publisher","DOI":"10.1165\/ajrcmb\/8.4.393"},{"key":"B457","doi-asserted-by":"publisher","DOI":"10.1016\/0091-6749(92)90326-W"},{"key":"B458","doi-asserted-by":"publisher","DOI":"10.1016\/0143-4179(92)90027-T"},{"key":"B459","doi-asserted-by":"publisher","DOI":"10.1165\/rcmb.2011-0020OC"},{"key":"B460","doi-asserted-by":"publisher","DOI":"10.1016\/0165-1838(80)90004-1"},{"key":"B461","first-page":"937","volume":"132","author":"Nagai A","year":"1985","journal-title":"Am Rev Respir Dis"},{"key":"B462","doi-asserted-by":"publisher","DOI":"10.1016\/0034-5687(94)90040-X"},{"key":"B463","doi-asserted-by":"publisher","DOI":"10.1016\/0034-5687(94)90135-X"},{"key":"B464","doi-asserted-by":"publisher","DOI":"10.1016\/0034-5687(95)00042-C"},{"key":"B465","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.1996.270.6.L907"},{"key":"B466","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.00300.2001"},{"key":"B467","doi-asserted-by":"publisher","DOI":"10.1096\/fj.11-191627"},{"key":"B468","volume-title":"The Comparative Anatomy and Physiology of the Nose and Paranasal Sinuses","author":"Negus VE","year":"1958"},{"key":"B469","doi-asserted-by":"publisher","DOI":"10.1111\/j.1462-5822.2005.00566.x"},{"key":"B470","first-page":"687","volume":"44","author":"Nettesheim P","year":"1970","journal-title":"J Nat Cancer Inst"},{"key":"B471","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0602526103"},{"key":"B472","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3940(95)12001-K"},{"key":"B473","doi-asserted-by":"publisher","DOI":"10.1679\/aohc.67.159"},{"key":"B474","doi-asserted-by":"publisher","DOI":"10.1093\/chemse\/bjr052"},{"key":"B475","doi-asserted-by":"publisher","DOI":"10.1136\/thx.33.6.779"},{"key":"B476","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2005.104661"},{"key":"B477","doi-asserted-by":"publisher","DOI":"10.1016\/S0091-6749(98)70013-2"},{"key":"B478","doi-asserted-by":"publisher","DOI":"10.1165\/ajrcmb\/9.5.557"},{"key":"B479","doi-asserted-by":"publisher","DOI":"10.1007\/s00795-009-0470-y"},{"key":"B480","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.00181.2006"},{"key":"B481","doi-asserted-by":"publisher","DOI":"10.1369\/jhc.5A6843.2006"},{"key":"B482","doi-asserted-by":"publisher","DOI":"10.1165\/ajrcmb\/8.2.176"},{"key":"B483","doi-asserted-by":"publisher","DOI":"10.1016\/S0046-8177(81)80240-7"},{"key":"B484","first-page":"241","volume":"2","author":"Oppenheimer EH","year":"1975","journal-title":"Perspect Pediatr Pathol"},{"key":"B485","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.163.2.2004039"},{"key":"B486","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00028.2003"},{"key":"B487","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.22967"},{"key":"B488","first-page":"493","volume":"138","author":"Pack RJ","year":"1984","journal-title":"J Anat"},{"key":"B489","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1988.sp017246"},{"key":"B490","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742-4658.2005.04711.x"},{"key":"B491","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm\/136.4_Pt_2.S50"},{"key":"B492","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.00464.2005"},{"key":"B493","doi-asserted-by":"publisher","DOI":"10.1007\/s00424-006-0061-x"},{"key":"B494","doi-asserted-by":"publisher","DOI":"10.1152\/physiol.00028.2012"},{"key":"B495","doi-asserted-by":"publisher","DOI":"10.1007\/BF00501920"},{"key":"B496","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.1991.261.2.L172"},{"key":"B497","doi-asserted-by":"publisher","DOI":"10.1007\/s00441-004-0877-7"},{"key":"B498","doi-asserted-by":"publisher","DOI":"10.1164\/arrd.1983.128.1.89"},{"key":"B499","doi-asserted-by":"publisher","DOI":"10.1042\/cs0710179"},{"key":"B500","first-page":"210","volume":"125","author":"Peatfield AC","year":"1982","journal-title":"Am Rev Respir Dis"},{"key":"B501","doi-asserted-by":"publisher","DOI":"10.1111\/j.1476-5381.1982.tb09310.x"},{"key":"B502","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1983.sp014853"},{"key":"B503","doi-asserted-by":"publisher","DOI":"10.1016\/0014-2999(82)90351-X"},{"key":"B504","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1983.sp014854"},{"key":"B505","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1986.sp016295"},{"key":"B506","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00039.2011"},{"key":"B507","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.87.19.7638"},{"key":"B508","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm\/148.2.455"},{"key":"B509","doi-asserted-by":"publisher","DOI":"10.1007\/s00424-005-1484-5"},{"key":"B510","doi-asserted-by":"publisher","DOI":"10.1378\/chest.130.4.1129"},{"key":"B511","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.E09-08-0655"},{"key":"B512","doi-asserted-by":"publisher","DOI":"10.1177\/0192623311409594"},{"key":"B513","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.149.5.8173772"},{"key":"B514","doi-asserted-by":"publisher","DOI":"10.1016\/j.colsurfa.2013.03.010"},{"key":"B515","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.85.7.2383"},{"key":"B516","doi-asserted-by":"publisher","DOI":"10.1038\/nature11130"},{"key":"B517","doi-asserted-by":"publisher","DOI":"10.1016\/S0169-2607(01)00170-5"},{"key":"B518","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjp.0705029"},{"key":"B519","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1986.60.3.918"},{"key":"B520","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1983.55.5.1593"},{"key":"B521","first-page":"359","volume":"121","author":"Phipps RJ","year":"1980","journal-title":"Am Rev Respir Dis"},{"key":"B522","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1976.sp011574"},{"key":"B523","doi-asserted-by":"publisher","DOI":"10.1042\/cs0630023"},{"key":"B524","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.01.00228801"},{"key":"B525","doi-asserted-by":"publisher","DOI":"10.1007\/BF00824332"},{"key":"B526","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1990.68.2.726"},{"key":"B527","volume-title":"The Nose, Upper Airway Physiology and the Atmospheric Environment","author":"Proctor DF","year":"1982"},{"key":"B528","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-065X.2011.01033.x"},{"key":"B529","doi-asserted-by":"publisher","DOI":"10.1165\/ajrcmb\/8.1.16"},{"key":"B530","doi-asserted-by":"publisher","DOI":"10.1159\/000196486"},{"key":"B531","doi-asserted-by":"publisher","DOI":"10.1111\/j.1768-322X.1985.tb00418.x"},{"key":"B532","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.00358.2009"},{"key":"B533","doi-asserted-by":"publisher","DOI":"10.1038\/279551a0"},{"key":"B534","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.1981.241.1.C25"},{"key":"B535","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.00362.2010"},{"key":"B536","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.00714.2007"},{"key":"B537","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1996.sp021515"},{"key":"B538","doi-asserted-by":"publisher","DOI":"10.1111\/j.1476-5381.1996.tb15498.x"},{"key":"B539","doi-asserted-by":"publisher","DOI":"10.1016\/0091-6749(89)90389-8"},{"key":"B540","doi-asserted-by":"publisher","DOI":"10.1172\/JCI114329"},{"key":"B541","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm\/151.3_Pt_1.800"},{"key":"B542","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1978.45.2.190"},{"key":"B543","first-page":"1121","volume":"78","author":"Redl B","year":"1998","journal-title":"Lab Invest"},{"key":"B544","doi-asserted-by":"publisher","DOI":"10.1136\/thx.15.2.132"},{"key":"B545","first-page":"195","volume":"10","author":"Reid L","year":"1967","journal-title":"Mod Probl Paediat"},{"key":"B546","doi-asserted-by":"publisher","DOI":"10.1136\/thx.18.4.334"},{"key":"B547","first-page":"1","volume":"93","author":"Rhodin JAG","year":"1966","journal-title":"Am Rev Respir Dis"},{"key":"B548","doi-asserted-by":"publisher","DOI":"10.1136\/thx.39.6.420"},{"key":"B549","doi-asserted-by":"publisher","DOI":"10.1165\/ajrcmb\/6.2.158"},{"key":"B550","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.1991.261.6.L415"},{"key":"B551","doi-asserted-by":"publisher","DOI":"10.1126\/science.2475911"},{"key":"B552","doi-asserted-by":"publisher","DOI":"10.1126\/science.1163600"},{"key":"B553","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.94.07091678"},{"key":"B554","doi-asserted-by":"publisher","DOI":"10.1016\/S0034-5687(00)00209-7"},{"key":"B555","doi-asserted-by":"publisher","DOI":"10.1016\/0014-2999(89)90322-1"},{"key":"B556","doi-asserted-by":"publisher","DOI":"10.1042\/cs0720629"},{"key":"B557","doi-asserted-by":"publisher","DOI":"10.1016\/j.mam.2012.10.008"},{"key":"B558","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00010.2005"},{"key":"B559","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0185(20000901)260:1<92::AID-AR100>3.0.CO;2-#"},{"key":"B560","first-page":"302","volume":"20","author":"Rossbach MJ","year":"1882","journal-title":"Berlin Klin Wochensch"},{"key":"B561","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.00081.2006"},{"key":"B562","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2004.070433"},{"key":"B563","doi-asserted-by":"publisher","DOI":"10.1038\/nature12807"},{"key":"B564","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm\/143.1.138"},{"key":"B565","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.01.00229501"},{"key":"B566","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.156.5.9701081"},{"key":"B567","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.2001.280.1.L79"},{"key":"B568","doi-asserted-by":"publisher","DOI":"10.1165\/ajrcmb.19.2.3239"},{"key":"B569","doi-asserted-by":"publisher","DOI":"10.1016\/0167-0115(91)90222-3"},{"key":"B570","doi-asserted-by":"publisher","DOI":"10.1096\/fj.04-2879fje"},{"key":"B571","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2222.1999.00644.x"},{"key":"B572","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1242\/jcs.47.1.331","volume":"47","author":"Sanderson MJ","year":"1981","journal-title":"J Cell Sci"},{"key":"B573","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.1989.257.6.L373"},{"key":"B574","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1989.66.2.764"},{"key":"B575","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.1994.267.2.L152"},{"key":"B576","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.00454.2003"},{"key":"B577","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.69.9.5243-5248.2001"},{"key":"B578","doi-asserted-by":"publisher","DOI":"10.1080\/01902140802341710"},{"key":"B579","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M110.113621"},{"key":"B580","doi-asserted-by":"publisher","DOI":"10.1126\/science.169.3950.1102"},{"key":"B581","doi-asserted-by":"publisher","DOI":"10.1002\/ar.1092100303"},{"key":"B582","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.95.16.9660"},{"key":"B583","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.1972.52.3.720"},{"key":"B584","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2008.09.003"},{"key":"B585","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1991.71.3.900"},{"key":"B586","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1985.58.3.907"},{"key":"B587","doi-asserted-by":"publisher","DOI":"10.1201\/b14423-9"},{"key":"B588","doi-asserted-by":"publisher","DOI":"10.1172\/JCI106113"},{"key":"B589","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.1992.262.1.L86"},{"key":"B590","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1407597111"},{"key":"B591","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M607527200"},{"key":"B592","doi-asserted-by":"publisher","DOI":"10.1016\/S0005-2736(03)00210-4"},{"key":"B593","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.00321.2010"},{"key":"B594","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.00371.2012"},{"key":"B595","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.87.23.9188"},{"key":"B596","doi-asserted-by":"publisher","DOI":"10.3168\/jds.S0022-0302(05)72719-3"},{"key":"B597","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-1716.2011.02253.x"},{"key":"B598","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2012.236893"},{"key":"B599","doi-asserted-by":"publisher","DOI":"10.1165\/ajrcmb.19.1.3054"},{"key":"B600","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-010-0500-x"},{"key":"B601","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M313323200"},{"key":"B602","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2008.154468"},{"key":"B603","doi-asserted-by":"publisher","DOI":"10.1042\/bj3380507"},{"key":"B604","doi-asserted-by":"publisher","DOI":"10.1002\/9780470035399.ch13"},{"key":"B605","doi-asserted-by":"publisher","DOI":"10.1172\/JCI109993"},{"key":"B606","doi-asserted-by":"publisher","DOI":"10.1016\/0091-6749(80)90138-4"},{"key":"B607","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.1994.266.5.L493"},{"key":"B608","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.96.09071395"},{"key":"B609","doi-asserted-by":"publisher","DOI":"10.1016\/0034-5687(93)90008-X"},{"key":"B610","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.1992.262.2.L208"},{"key":"B611","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1988.65.6.2537"},{"key":"B612","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm\/141.4_Pt_1.1044"},{"key":"B613","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.1992.262.1.L15"},{"key":"B614","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.1994.267.2.L159"},{"key":"B615","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1987.63.2.646"},{"key":"B616","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1986.60.4.1237"},{"key":"B617","first-page":"325","volume-title":"Airway Secretion Physiological Bases for the Control of Mucous Hypersecretion","author":"Shimura S","year":"1994"},{"key":"B618","doi-asserted-by":"publisher","DOI":"10.1016\/0006-3002(52)90045-0"},{"key":"B619","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.157.6.9706014"},{"key":"B620","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.1997.273.5.L1036"},{"key":"B621","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.00454.2009"},{"key":"B622","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.95.25.14961"},{"key":"B623","doi-asserted-by":"publisher","DOI":"10.1038\/417552a"},{"key":"B624","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.2000.279.5.L799"},{"key":"B625","doi-asserted-by":"publisher","DOI":"10.1002\/prca.201100046"},{"key":"B626","doi-asserted-by":"publisher","DOI":"10.3233\/BIR-1990-273-431"},{"key":"B627","first-page":"223","volume":"127","author":"Smolich JJ","year":"1978","journal-title":"J Anat"},{"key":"B628","doi-asserted-by":"publisher","DOI":"10.1093\/chemse\/bjr063"},{"key":"B629","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1991.70.5.2259"},{"key":"B630","doi-asserted-by":"publisher","DOI":"10.1165\/ajrcmb\/6.1.116"},{"key":"B631","doi-asserted-by":"publisher","DOI":"10.1165\/ajrcmb\/2.1.41"},{"key":"B632","doi-asserted-by":"publisher","DOI":"10.1172\/JCI114492"},{"key":"B633","doi-asserted-by":"publisher","DOI":"10.1016\/j.archoralbio.2008.01.002"},{"key":"B634","doi-asserted-by":"publisher","DOI":"10.1085\/jgp.117.6.573"},{"key":"B635","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.00379.2005"},{"key":"B636","doi-asserted-by":"publisher","DOI":"10.1002\/aja.1001170302"},{"key":"B637","doi-asserted-by":"publisher","DOI":"10.1080\/09629359891342"},{"key":"B638","doi-asserted-by":"publisher","DOI":"10.1136\/thx.32.4.387"},{"key":"B639","doi-asserted-by":"publisher","DOI":"10.1136\/thx.31.2.158"},{"key":"B640","doi-asserted-by":"publisher","DOI":"10.1002\/ar.1092020106"},{"key":"B641","first-page":"92","volume":"14","author":"Spring K","year":"1999","journal-title":"News Physiol Sci"},{"key":"B642","doi-asserted-by":"publisher","DOI":"10.1002\/ar.1092160111"},{"key":"B643","doi-asserted-by":"publisher","DOI":"10.1016\/0014-2999(87)90075-6"},{"key":"B644","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.physiol.67.031103.153247"},{"key":"B645","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.00089.2011"},{"key":"B646","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.3000928"},{"key":"B647","first-page":"303","volume":"106","author":"Sturgess J","year":"1982","journal-title":"Am J Pathol"},{"key":"B648","first-page":"388","volume":"54","author":"Sturgess J","year":"1973","journal-title":"Br J Exp Pathol"},{"key":"B649","doi-asserted-by":"publisher","DOI":"10.1042\/cs0430533"},{"key":"B650","first-page":"129","volume":"19","author":"Sturgess JM","year":"1977","journal-title":"Mod Probl Paediat"},{"key":"B651","first-page":"819","volume":"115","author":"Sturgess JM","year":"1977","journal-title":"Am Rev Respir Dis"},{"key":"B652","doi-asserted-by":"publisher","DOI":"10.1126\/science.1161748"},{"key":"B653","doi-asserted-by":"publisher","DOI":"10.1172\/JCI43052"},{"key":"B654","doi-asserted-by":"publisher","DOI":"10.1042\/BST0370814"},{"key":"B655","doi-asserted-by":"publisher","DOI":"10.1136\/thx.14.4.286"},{"key":"B656","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-201X.1997.00125.x"},{"key":"B657","first-page":"125","volume":"131","author":"Takemura T","year":"1985","journal-title":"Am Rev Respir Dis"},{"key":"B658","doi-asserted-by":"publisher","DOI":"10.1164\/arrd.1971.104.3.331"},{"key":"B659","first-page":"774","volume":"103","author":"Takizawa T","year":"1971","journal-title":"Am Rev Respir Dis"},{"key":"B660","doi-asserted-by":"publisher","DOI":"10.1038\/292340a0"},{"key":"B661","doi-asserted-by":"publisher","DOI":"10.1165\/rcmb.2006-0389OC"},{"key":"B662","doi-asserted-by":"publisher","DOI":"10.1165\/ajrcmb.22.5.3847"},{"key":"B663","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.89.23.11229"},{"key":"B664","doi-asserted-by":"publisher","DOI":"10.1002\/aja.1001110304"},{"key":"B665","doi-asserted-by":"publisher","DOI":"10.1002\/jmor.1051270402"},{"key":"B666","first-page":"469","volume":"124","author":"Tandler B","year":"1981","journal-title":"Am Rev Respir Dis"},{"key":"B667","doi-asserted-by":"publisher","DOI":"10.1016\/j.biocel.2014.03.002"},{"key":"B668","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-4838(00)00167-9"},{"key":"B669","doi-asserted-by":"publisher","DOI":"10.1096\/fj.03-1248fje"},{"key":"B670","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2010.05.046"},{"key":"B671","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-61779-120-8_8"},{"key":"B672","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.physiol.70.113006.100702"},{"key":"B673","doi-asserted-by":"publisher","DOI":"10.1513\/pats.2306016"},{"key":"B674","volume-title":"Chronic Airflow Obstruction in Lung Disease","author":"Thurlbeck WM","year":"1976"},{"key":"B675","doi-asserted-by":"publisher","DOI":"10.1136\/thx.19.5.436"},{"key":"B676","first-page":"815","volume":"87","author":"Thurlbeck WM","year":"1963","journal-title":"Am Rev Respir Dis"},{"key":"B677","first-page":"551","volume":"95","author":"Thurlbeck WM","year":"1967","journal-title":"Am Rev Respir Dis"},{"key":"B678","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2009.11.045"},{"key":"B679","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.1990.259.2.L108"},{"key":"B680","doi-asserted-by":"publisher","DOI":"10.1007\/BF00211475"},{"key":"B681","first-page":"376","volume":"123","author":"Tos M","year":"1968","journal-title":"Anat Anz"},{"key":"B682","first-page":"1","volume":"185","author":"Tos M","year":"1966","journal-title":"Acta Pathol Microbiol Scand Suppl"},{"key":"B683","first-page":"269","volume":"64","author":"Tos M","year":"1983","journal-title":"Eur J Respir Dis"},{"key":"B684","doi-asserted-by":"publisher","DOI":"10.1007\/BF00453608"},{"key":"B685","first-page":"131","volume":"360","author":"Tos M","year":"1979","journal-title":"Acta Otolaryngol Suppl"},{"key":"B686","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1983.00800240039007"},{"key":"B687","doi-asserted-by":"publisher","DOI":"10.1007\/BF00455856"},{"key":"B688","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm\/141.5_Pt_1.1280"},{"key":"B689","doi-asserted-by":"crossref","first-page":"25454","DOI":"10.1016\/S0021-9258(18)47272-9","volume":"269","author":"Tournier JM","year":"1994","journal-title":"J Biol Chem"},{"key":"B690","doi-asserted-by":"publisher","DOI":"10.1016\/S0952-7915(00)00187-4"},{"key":"B691","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.2001.281.3.L639"},{"key":"B692","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.1998.275.6.L1095"},{"key":"B693","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.1998.274.2.L258"},{"key":"B694","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2002.035923"},{"key":"B695","doi-asserted-by":"publisher","DOI":"10.1016\/j.exppara.2012.01.002"},{"key":"B697","doi-asserted-by":"publisher","DOI":"10.1177\/019459989210600126"},{"key":"B698","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0091253"},{"key":"B699","first-page":"56","volume":"16","author":"Tuvim MJ","year":"2001","journal-title":"News Physiol Sci"},{"key":"B700","doi-asserted-by":"publisher","DOI":"10.3109\/00016487809124767"},{"key":"B701","first-page":"351","volume":"121","author":"Ueki I","year":"1980","journal-title":"Am Rev Respir Dis"},{"key":"B702","first-page":"622","volume":"40","author":"Ueki I","year":"1981","journal-title":"Federation Proc"},{"key":"B703","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-1716.1951.tb00800.x"},{"key":"B704","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2222.1998.00198.x"},{"key":"B705","doi-asserted-by":"publisher","DOI":"10.1165\/ajrcmb.13.3.7654389"},{"key":"B706","doi-asserted-by":"publisher","DOI":"10.1016\/S0091-6749(95)70153-2"},{"key":"B707","first-page":"425","volume":"24","author":"Vatrella A","year":"2010","journal-title":"J Biol Regul Homeost Agents"},{"key":"B708","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.00417.2002"},{"key":"B709","first-page":"37","volume":"1","author":"Virtue JA","year":"1972","journal-title":"Can J Otolaryngol"},{"key":"B710","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1128\/IAI.45.1.197-202.1984","volume":"45","author":"Vishwanath S","year":"1984","journal-title":"Infect Immunol"},{"key":"B711","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbagen.2012.03.017"},{"key":"B712","doi-asserted-by":"publisher","DOI":"10.1378\/chest.08-0412"},{"key":"B713","doi-asserted-by":"publisher","DOI":"10.1016\/S0196-9781(97)00257-X"},{"key":"B714","doi-asserted-by":"publisher","DOI":"10.1016\/0024-3205(95)00271-7"},{"key":"B715","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.154.6.8970383"},{"key":"B716","first-page":"115","volume":"130","author":"Warner T","year":"1984","journal-title":"Am Rev Respir Dis"},{"key":"B717","doi-asserted-by":"publisher","DOI":"10.1172\/JCI67911"},{"key":"B718","doi-asserted-by":"publisher","DOI":"10.1006\/pupt.1997.0089"},{"key":"B719","doi-asserted-by":"publisher","DOI":"10.1007\/BF01968821"},{"key":"B720","doi-asserted-by":"publisher","DOI":"10.1111\/j.1476-5381.1987.tb08992.x"},{"key":"B721","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-87553-3"},{"key":"B722","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1986.sp016084"},{"key":"B723","doi-asserted-by":"publisher","DOI":"10.1016\/0952-0600(92)90039-J"},{"key":"B724","doi-asserted-by":"publisher","DOI":"10.1006\/pulp.1993.1017"},{"key":"B725","doi-asserted-by":"publisher","DOI":"10.1007\/BF01870565"},{"key":"B726","first-page":"24","volume":"4","author":"Whimster WF","year":"1986","journal-title":"Appl Pathol"},{"key":"B727","first-page":"241","volume":"6","author":"Whimster WF","year":"1988","journal-title":"Appl Pathol"},{"key":"B728","doi-asserted-by":"publisher","DOI":"10.1136\/thx.48.3.290"},{"key":"B730","doi-asserted-by":"publisher","DOI":"10.1201\/b14041-4"},{"key":"B731","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.165.11.165111"},{"key":"B732","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.82.2.380"},{"key":"B733","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.97.10122892"},{"key":"B734","doi-asserted-by":"publisher","DOI":"10.1046\/j.1469-7580.2001.19820207.x"},{"key":"B735","doi-asserted-by":"publisher","DOI":"10.2746\/042516402776180151"},{"key":"B736","first-page":"51","volume":"39","author":"Widdicombe JH","year":"2003","journal-title":"In Vitro"},{"key":"B737","doi-asserted-by":"publisher","DOI":"10.1002\/jemt.1070320308"},{"key":"B738","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.159.4.9804149"},{"key":"B739","doi-asserted-by":"publisher","DOI":"10.1201\/b14423-5"},{"key":"B740","doi-asserted-by":"publisher","DOI":"10.1165\/rcmb.2002-0152OC"},{"key":"B741","doi-asserted-by":"publisher","DOI":"10.1016\/j.autneu.2007.01.008"},{"key":"B742","doi-asserted-by":"publisher","DOI":"10.1513\/pats.2306015"},{"key":"B743","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-61779-120-8_6"},{"key":"B744","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.1991.261.2.L218"},{"key":"B745","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1242\/jcs.102.2.185","volume":"102","author":"Wollner DA","year":"1992","journal-title":"J Cell Sci"},{"key":"B746","doi-asserted-by":"publisher","DOI":"10.1055\/s-2002-34331"},{"key":"B747","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M405517200"},{"key":"B748","doi-asserted-by":"publisher","DOI":"10.1006\/bbrc.1994.1928"},{"key":"B749","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.1998.274.3.L388"},{"key":"B750","doi-asserted-by":"publisher","DOI":"10.1172\/JCI16889"},{"key":"B751","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M406058200"},{"key":"B752","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.00286.2006"},{"key":"B753","doi-asserted-by":"publisher","DOI":"10.1165\/rcmb.2013-0259MA"},{"key":"B754","doi-asserted-by":"publisher","DOI":"10.1165\/rcmb.2009-0329OC"},{"key":"B755","doi-asserted-by":"publisher","DOI":"10.1172\/JCI41857"},{"key":"B756","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmed.2012.04.001"},{"key":"B757","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.1991.261.6.L491"},{"key":"B758","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.1991.261.6.L485"},{"key":"B759","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1988.64.1.200"},{"key":"B760","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1988.65.4.1891"},{"key":"B761","doi-asserted-by":"publisher","DOI":"10.1038\/nature07313"},{"key":"B762","first-page":"837","volume":"114","author":"Yoneda K","year":"1976","journal-title":"Am Rev Respir Dis"},{"key":"B763","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1989.67.2.682"},{"key":"B764","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.3010525"},{"key":"B765","doi-asserted-by":"publisher","DOI":"10.1111\/j.1476-5381.1991.tb12548.x"},{"key":"B766","first-page":"269","volume":"17","author":"Zeitlin IJ","year":"1978","journal-title":"Adv Biosci"},{"key":"B767","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.00366.2012"},{"key":"B768","doi-asserted-by":"publisher","DOI":"10.1016\/j.preteyeres.2012.06.002"},{"key":"B769","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200602-161OC"},{"key":"B770","doi-asserted-by":"publisher","DOI":"10.1016\/j.resp.2010.08.002"},{"key":"B771","doi-asserted-by":"publisher","DOI":"10.1080\/089583701300001050"}],"container-title":["Physiological Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.physiology.org\/doi\/pdf\/10.1152\/physrev.00039.2014","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,13]],"date-time":"2023-08-13T17:50:41Z","timestamp":1691949041000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.physiology.org\/doi\/10.1152\/physrev.00039.2014"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,10]]},"references-count":768,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2015,10]]}},"alternative-id":["10.1152\/physrev.00039.2014"],"URL":"https:\/\/doi.org\/10.1152\/physrev.00039.2014","relation":{},"ISSN":["0031-9333","1522-1210"],"issn-type":[{"value":"0031-9333","type":"print"},{"value":"1522-1210","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,10]]}}}