{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T09:16:18Z","timestamp":1791191778891,"version":"4.1.0"},"reference-count":429,"publisher":"American Physiological Society","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Physiological Reviews"],"published-print":{"date-parts":[[1999,1,1]]},"abstract":"<jats:p>Rossini, Aldo A., Dale L. Greiner, and John P. Mordes. Induction of Immunologic Tolerance for Transplantation. Physiol. Rev. 79: 99\u2013141, 1999. \u2014 In the second half of the 20th century, the transplantation of replacement organs and tissues to cure disease has become a clinical reality. Success has been achieved as a direct result of progress in understanding the cellular and molecular biology of the immune system. This understanding has led to the development of immunosuppressive pharmaceuticals that are part of nearly every transplantation procedure. All such drugs are toxic to some degree, however, and their chronic use, mandatory in transplantation, predisposes the patient to the development of infection and cancer. In addition, many of them may have deleterious long-term effects on the function of grafts. New immunosuppressive agents are constantly under development, but organ transplantation remains a therapy that requires patients to choose between the risks of their primary illness and its treatment on the one hand, and the risks of life-long systemic immunosuppression on the other. Alternatives to immunosuppression include modulation of donor grafts to reduce immunogenicity, removal of passenger leukocytes, transplantation into immunologically privileged sites like the testis or thymus, encapsulation of tissue, and the induction of a state of immunologic tolerance. It is the last of these alternatives that has, perhaps, the most promise and most generic applicability as a future therapy. Recent reports documenting long-term graft survival in the absence of immunosuppression suggest that tolerance-based therapies may soon become a clinical reality. Of particular interest to our laboratory are transplantation strategies that focus on the induction of donor-specific T-cell unresponsiveness. The basic biology, protocols, experimental outcomes, and clinical implications of tolerance-based transplantation are the focus of this review.<\/jats:p>","DOI":"10.1152\/physrev.1999.79.1.99","type":"journal-article","created":{"date-parts":[[2017,12,24]],"date-time":"2017-12-24T20:21:04Z","timestamp":1514146864000},"page":"99-141","source":"Crossref","is-referenced-by-count":96,"title":["Induction of Immunologic Tolerance for Transplantation"],"prefix":"10.1152","volume":"79","author":[{"given":"ALDO A.","family":"ROSSINI","sequence":"first","affiliation":[{"name":"Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"DALE L.","family":"GREINER","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"JOHN P.","family":"MORDES","sequence":"additional","affiliation":[{"name":"Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"24","reference":[{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1038\/350207a0"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1016\/S0025-6196(12)60373-5"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.94.8.3943"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1084\/jem.173.2.491"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199309000-00026"},{"key":"B8","doi-asserted-by":"crossref","first-page":"2964","DOI":"10.1182\/blood.V80.12.2964.2964","volume":"80","author":"ANTIN J. H.","year":"1992","journal-title":"Blood"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1084\/jem.165.3.891"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1016\/0167-5699(93)90317-E"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-198807000-00001"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.90.8.3373"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199705150-00026"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.93.22.12439"},{"key":"B15","first-page":"S136","volume":"14","author":"AZUMA H.","year":"1995","journal-title":"J. Heart Lung Transplant."},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1038\/366076a0"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1038\/nm0298-141"},{"key":"B18","doi-asserted-by":"crossref","first-page":"4620","DOI":"10.4049\/jimmunol.159.9.4620","volume":"159","author":"BALASA B.","year":"1997","journal-title":"J. Immunol."},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1084\/jem.176.4.1099"},{"key":"B20","first-page":"1","volume":"25","author":"BARKER C. F.","year":"1977","journal-title":"Adv. Immunol."},{"key":"B21","first-page":"393","volume":"17","author":"BARTLETT S. T.","year":"1985","journal-title":"Transplant. Proc."},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1038\/377630a0"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.3109\/08830189609061750"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-5699(97)01004-9"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1084\/jem.182.3.639"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1093\/intimm\/4.6.661"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1038\/172603a0"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199603150-00022"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-5699(97)82722-3"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199711270-00001"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.1093\/intimm\/9.3.365"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1126\/science.1972592"},{"key":"B33","doi-asserted-by":"crossref","first-page":"29","DOI":"10.4049\/jimmunol.158.1.29","volume":"158","author":"BLAZAR B. R.","year":"1997","journal-title":"J. Immunol."},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.1016\/1074-7613(95)90000-4"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9343(96)00124-6"},{"key":"B37","first-page":"329","volume":"33","author":"BLUMBERG N.","year":"1996","journal-title":"Semin. Hematol."},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.85.24.9719"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.1006\/jsre.1994.1110"},{"key":"B40","doi-asserted-by":"crossref","first-page":"5038","DOI":"10.4049\/jimmunol.153.11.5038","volume":"153","author":"BORRIELLO F.","year":"1994","journal-title":"J. Immunol."},{"key":"B41","doi-asserted-by":"crossref","first-page":"1713","DOI":"10.4049\/jimmunol.155.4.1713","volume":"155","author":"BRADLEY L. M.","year":"1995","journal-title":"J. Immunol."},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199301000-00033"},{"key":"B43","doi-asserted-by":"publisher","DOI":"10.1126\/science.169.3950.1042"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.1038\/328267a0"},{"key":"B45","doi-asserted-by":"publisher","DOI":"10.1016\/1074-7613(95)90009-8"},{"key":"B46","doi-asserted-by":"publisher","DOI":"10.1016\/S0041-1345(96)00553-2"},{"key":"B49","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199304000-00034"},{"key":"B50","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199403270-00030"},{"key":"B51","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2567.1997.00421.x"},{"key":"B52","doi-asserted-by":"publisher","DOI":"10.1084\/jem.185.12.2053"},{"key":"B53","first-page":"3523","volume":"26","author":"CARROLL P. B.","year":"1994","journal-title":"Transplant. Proc."},{"key":"B54","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199505000-00016"},{"key":"B55","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.iy.12.040194.003011"},{"key":"B56","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199504270-00014"},{"key":"B57","doi-asserted-by":"publisher","DOI":"10.1002\/eji.1830250213"},{"key":"B58","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.iy.12.040194.003423"},{"key":"B59","doi-asserted-by":"publisher","DOI":"10.1016\/1074-7613(94)90108-2"},{"key":"B60","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199512000-00002"},{"key":"B61","doi-asserted-by":"publisher","DOI":"10.1038\/376177a0"},{"key":"B62","doi-asserted-by":"publisher","DOI":"10.1126\/science.7520605"},{"key":"B63","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.93.1.388"},{"key":"B64","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)80178-6"},{"key":"B65","doi-asserted-by":"publisher","DOI":"10.1038\/350203a0"},{"key":"B66","doi-asserted-by":"publisher","DOI":"10.1016\/S0065-2776(08)60854-8"},{"key":"B68","doi-asserted-by":"crossref","first-page":"4790","DOI":"10.4049\/jimmunol.157.11.4790","volume":"157","author":"COULOMBE M.","year":"1996","journal-title":"J. Immunol."},{"key":"B69","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.94.20.10850"},{"key":"B70","doi-asserted-by":"publisher","DOI":"10.1084\/jem.176.5.1431"},{"key":"B71","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199503150-00003"},{"key":"B72","doi-asserted-by":"crossref","first-page":"3104","DOI":"10.4049\/jimmunol.159.7.3104","volume":"159","author":"DAIKH D. I.","year":"1997","journal-title":"J. Immunol."},{"key":"B73","doi-asserted-by":"publisher","DOI":"10.1084\/jem.173.1.79"},{"key":"B74","doi-asserted-by":"publisher","DOI":"10.1084\/jem.165.2.566"},{"key":"B75","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(97)08496-1"},{"key":"B76","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199209000-00019"},{"key":"B77","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780401002"},{"key":"B78","doi-asserted-by":"crossref","first-page":"529","DOI":"10.4049\/jimmunol.157.2.529","volume":"157","author":"DAVIES J. D.","year":"1996","journal-title":"J. Immunol."},{"key":"B79","doi-asserted-by":"crossref","first-page":"353","DOI":"10.4049\/jimmunol.150.2.353","volume":"150","author":"DEL PRETE G.","year":"1993","journal-title":"J. Immunol."},{"key":"B80","first-page":"563","volume":"150","author":"DEMETRIS A. J.","year":"1997","journal-title":"Am. J. Pathol."},{"key":"B83","doi-asserted-by":"crossref","first-page":"1224","DOI":"10.4049\/jimmunol.151.3.1224","volume":"151","author":"DING L.","year":"1993","journal-title":"J. Immunol."},{"key":"B84","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199504150-00001"},{"key":"B85","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-198205000-00011"},{"key":"B86","doi-asserted-by":"crossref","first-page":"1250","DOI":"10.4049\/jimmunol.157.3.1250","volume":"157","author":"DOUILLARD P.","year":"1996","journal-title":"J. Immunol."},{"key":"B87","doi-asserted-by":"crossref","first-page":"45","DOI":"10.4049\/jimmunol.155.1.45","volume":"155","author":"DUBEY C.","year":"1995","journal-title":"J. Immunol."},{"key":"B88","doi-asserted-by":"publisher","DOI":"10.1172\/JCI117453"},{"key":"B89","doi-asserted-by":"publisher","DOI":"10.1126\/science.7689748"},{"key":"B90","doi-asserted-by":"crossref","first-page":"3159","DOI":"10.4049\/jimmunol.157.7.3159","volume":"157","author":"EARLY G. S.","year":"1996","journal-title":"J. Immunol."},{"key":"B91","doi-asserted-by":"publisher","DOI":"10.1084\/jem.175.1.131"},{"key":"B92","doi-asserted-by":"crossref","first-page":"2958","DOI":"10.4049\/jimmunol.151.6.2958","volume":"151","author":"EYNON E. E.","year":"1993","journal-title":"J. Immunol."},{"key":"B93","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-7799(00)88914-3"},{"key":"B94","doi-asserted-by":"publisher","DOI":"10.1126\/science.1710828"},{"key":"B95","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.78.8.5156"},{"key":"B96","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199705150-00023"},{"key":"B97","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199707150-00002"},{"key":"B98","first-page":"247","volume":"4","author":"FINKELMAN F. D.","year":"1992","journal-title":"Semin. Immunol."},{"key":"B99","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199807093390202"},{"key":"B100","doi-asserted-by":"publisher","DOI":"10.1002\/eji.1830241122"},{"key":"B101","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(94)92756-1"},{"key":"B102","doi-asserted-by":"publisher","DOI":"10.1126\/science.271.5256.1728"},{"key":"B103","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.immunol.14.1.591"},{"key":"B104","doi-asserted-by":"publisher","DOI":"10.1177\/096368979800700105"},{"key":"B105","doi-asserted-by":"publisher","DOI":"10.1002\/eji.1830271216"},{"key":"B106","doi-asserted-by":"publisher","DOI":"10.1126\/science.7694362"},{"key":"B107","doi-asserted-by":"publisher","DOI":"10.1016\/1074-7613(95)90032-2"},{"key":"B108","doi-asserted-by":"publisher","DOI":"10.1126\/science.1439825"},{"key":"B109","doi-asserted-by":"publisher","DOI":"10.1016\/0167-5699(93)90261-I"},{"key":"B110","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199607270-00018"},{"key":"B111","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199612270-00029"},{"key":"B112","doi-asserted-by":"publisher","DOI":"10.1126\/science.281.5373.96"},{"key":"B113","doi-asserted-by":"crossref","first-page":"5649","DOI":"10.4049\/jimmunol.154.11.5649","volume":"154","author":"GARSIDE P.","year":"1995","journal-title":"J. Immunol."},{"key":"B114","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.93.6.2499"},{"key":"B115","doi-asserted-by":"publisher","DOI":"10.1016\/0952-7915(94)90017-5"},{"key":"B116","doi-asserted-by":"publisher","DOI":"10.1084\/jem.179.1.249"},{"key":"B118","doi-asserted-by":"publisher","DOI":"10.2337\/diab.47.8.1199"},{"key":"B119","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199601150-00003"},{"key":"B120","doi-asserted-by":"publisher","DOI":"10.2337\/diab.43.1.16"},{"key":"B121","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-199210000-00003"},{"key":"B122","doi-asserted-by":"publisher","DOI":"10.1007\/BF02786323"},{"key":"B123","doi-asserted-by":"publisher","DOI":"10.1126\/science.273.5283.1864"},{"key":"B124","doi-asserted-by":"publisher","DOI":"10.1038\/378617a0"},{"key":"B125","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.92.3.811"},{"key":"B126","doi-asserted-by":"publisher","DOI":"10.1126\/science.270.5239.1189"},{"key":"B127","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-5699(97)81663-5"},{"key":"B128","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(94)90570-3"},{"key":"B129","doi-asserted-by":"publisher","DOI":"10.1084\/jem.184.1.19"},{"key":"B130","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.90.9.3913"},{"key":"B131","doi-asserted-by":"publisher","DOI":"10.1084\/jem.176.2.553"},{"key":"B132","doi-asserted-by":"crossref","first-page":"2522","DOI":"10.4049\/jimmunol.159.5.2522","volume":"159","author":"GUERETTE B.","year":"1997","journal-title":"J. Immunol."},{"key":"B133","doi-asserted-by":"publisher","DOI":"10.1084\/jem.181.4.1345"},{"key":"B134","first-page":"143","volume":"124","author":"GUTTMANN R. D.","year":"1981","journal-title":"CMA J."},{"key":"B135","first-page":"37","volume":"16","author":"GUTTMANN R. D.","year":"1984","journal-title":"Transplant. Proc."},{"key":"B136","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199709270-00018"},{"key":"B137","doi-asserted-by":"publisher","DOI":"10.1084\/jem.162.5.1683"},{"key":"B139","doi-asserted-by":"publisher","DOI":"10.1084\/jem.169.3.909"},{"key":"B140","doi-asserted-by":"crossref","first-page":"3099","DOI":"10.4049\/jimmunol.158.7.3099","volume":"158","author":"HARGREAVES R. G.","year":"1997","journal-title":"J. Immunol."},{"key":"B141","doi-asserted-by":"publisher","DOI":"10.1016\/0008-8749(83)90212-5"},{"key":"B142","doi-asserted-by":"crossref","first-page":"3245","DOI":"10.1182\/blood.V90.9.3245","volume":"90","author":"HART D. N. J.","year":"1997","journal-title":"Blood"},{"key":"B143","doi-asserted-by":"publisher","DOI":"10.1126\/science.7694361"},{"key":"B144","doi-asserted-by":"publisher","DOI":"10.1084\/jem.180.2.631"},{"key":"B145","first-page":"7","volume":"28","author":"HAYRY P.","year":"1996","journal-title":"Transplant. Proc."},{"key":"B146","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-065X.1993.tb00639.x"},{"key":"B147","doi-asserted-by":"publisher","DOI":"10.1038\/359547a0"},{"key":"B148","doi-asserted-by":"publisher","DOI":"10.1038\/35393"},{"key":"B150","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.89.7.2526"},{"key":"B151","doi-asserted-by":"crossref","first-page":"1447","DOI":"10.4049\/jimmunol.143.5.1447","volume":"143","author":"HORI S.","year":"1989","journal-title":"J. Immunol."},{"key":"B152","doi-asserted-by":"publisher","DOI":"10.1126\/science.277.5325.563"},{"key":"B153","doi-asserted-by":"publisher","DOI":"10.1084\/jem.174.2.467"},{"key":"B154","doi-asserted-by":"crossref","first-page":"582","DOI":"10.4049\/jimmunol.157.2.582","volume":"157","author":"INOBE M.","year":"1996","journal-title":"J. Immunol."},{"key":"B155","doi-asserted-by":"publisher","DOI":"10.1006\/bbrc.1994.1469"},{"key":"B156","doi-asserted-by":"publisher","DOI":"10.1126\/science.1347662"},{"key":"B157","doi-asserted-by":"publisher","DOI":"10.1016\/S0171-2985(96)80036-2"},{"key":"B158","doi-asserted-by":"crossref","first-page":"1585","DOI":"10.4049\/jimmunol.144.5.1585","volume":"144","author":"JENKINS M. K.","year":"1990","journal-title":"J. Immunol."},{"key":"B159","doi-asserted-by":"publisher","DOI":"10.1084\/jem.165.2.302"},{"key":"B160","doi-asserted-by":"publisher","DOI":"10.1002\/eji.1830270702"},{"key":"B161","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199511270-00013"},{"key":"B162","doi-asserted-by":"publisher","DOI":"10.1038\/369031a0"},{"key":"B163","doi-asserted-by":"publisher","DOI":"10.1038\/nm0797-738"},{"key":"B164","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(87)90568-X"},{"key":"B165","doi-asserted-by":"publisher","DOI":"10.1084\/jem.184.2.783"},{"key":"B166","doi-asserted-by":"publisher","DOI":"10.1084\/jem.184.1.173"},{"key":"B167","doi-asserted-by":"publisher","DOI":"10.1002\/eji.1830181238"},{"key":"B167a","doi-asserted-by":"publisher","DOI":"10.1038\/icb.1994.14"},{"key":"B168","doi-asserted-by":"publisher","DOI":"10.1002\/eji.1830240118"},{"key":"B170","first-page":"275","volume":"313","author":"KERMAN R. H.","year":"1997","journal-title":"Am. J. Med. Sci."},{"key":"B170a","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199709150-00008"},{"key":"B171","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.94.16.8789"},{"key":"B172","doi-asserted-by":"publisher","DOI":"10.1038\/333742a0"},{"key":"B175","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199701150-00002"},{"key":"B176","doi-asserted-by":"crossref","first-page":"152","DOI":"10.4049\/jimmunol.159.1.152","volume":"159","author":"KNECHTLE S. J.","year":"1997","journal-title":"J. Immunol."},{"key":"B177","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1182\/blood.V82.1.176.bloodjournal821176","volume":"82","author":"KOBATA T.","year":"1993","journal-title":"Blood"},{"key":"B178","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199504273321702"},{"key":"B179","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9861(19960624)370:2<203::AID-CNE6>3.0.CO;2-6"},{"key":"B180","first-page":"3466","volume":"26","author":"KOULMANDA M.","year":"1994","journal-title":"Transplant. Proc."},{"key":"B181","doi-asserted-by":"publisher","DOI":"10.1126\/science.7809629"},{"key":"B182","doi-asserted-by":"publisher","DOI":"10.1084\/jem.184.5.2013"},{"key":"B183","doi-asserted-by":"publisher","DOI":"10.1016\/S0952-7915(96)80062-8"},{"key":"B184","doi-asserted-by":"publisher","DOI":"10.1084\/jem.182.2.459"},{"key":"B185","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(95)90349-6"},{"key":"B187","doi-asserted-by":"crossref","first-page":"1687","DOI":"10.4049\/jimmunol.160.4.1687","volume":"160","author":"KWEON M.-N.","year":"1998","journal-title":"J. Immunol."},{"key":"B189","first-page":"76","volume":"1","author":"LACY P. E.","year":"1993","journal-title":"Diabetes Rev."},{"key":"B190","doi-asserted-by":"publisher","DOI":"10.1126\/science.107588"},{"key":"B191","first-page":"323","volume":"2","author":"LAFFERTY K. J.","year":"1989","journal-title":"Diabetes Nutr. Metab."},{"key":"B192","doi-asserted-by":"publisher","DOI":"10.1126\/science.1118726"},{"key":"B193","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.iy.01.040183.001043"},{"key":"B194","doi-asserted-by":"crossref","first-page":"2443","DOI":"10.4049\/jimmunol.158.5.2443","volume":"158","author":"LAKKIS F. G.","year":"1997","journal-title":"J. Immunol."},{"key":"B195","doi-asserted-by":"publisher","DOI":"10.1615\/CritRevImmunol.v16.i1.40"},{"key":"B196","doi-asserted-by":"publisher","DOI":"10.1084\/jem.157.5.1434"},{"key":"B197","doi-asserted-by":"publisher","DOI":"10.1002\/eji.1830221016"},{"key":"B198","doi-asserted-by":"publisher","DOI":"10.1084\/jem.185.3.405"},{"key":"B199","doi-asserted-by":"publisher","DOI":"10.1016\/S0039-6060(97)90175-6"},{"key":"B200","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199601150-00002"},{"key":"B201","doi-asserted-by":"publisher","DOI":"10.1038\/381434a0"},{"key":"B202","doi-asserted-by":"crossref","first-page":"5208","DOI":"10.4049\/jimmunol.152.11.5208","volume":"152","author":"LARSEN C. P.","year":"1994","journal-title":"J. Immunol."},{"key":"B203","doi-asserted-by":"publisher","DOI":"10.1126\/science.6410509"},{"key":"B204","doi-asserted-by":"publisher","DOI":"10.1126\/science.273.5271.109"},{"key":"B205","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199210000-00030"},{"key":"B206","doi-asserted-by":"publisher","DOI":"10.1038\/380717a0"},{"key":"B207","doi-asserted-by":"publisher","DOI":"10.1084\/jem.155.1.31"},{"key":"B208","doi-asserted-by":"publisher","DOI":"10.1084\/jem.179.3.865"},{"key":"B209","doi-asserted-by":"publisher","DOI":"10.1084\/jem.171.3.729"},{"key":"B210","doi-asserted-by":"publisher","DOI":"10.1172\/JCI113187"},{"key":"B211","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199710270-00017"},{"key":"B212","first-page":"A75","volume":"47","author":"LEHMANN R.","year":"1998","journal-title":"Diabetes"},{"key":"B213","doi-asserted-by":"publisher","DOI":"10.1084\/jem.181.3.1145"},{"key":"B214","doi-asserted-by":"publisher","DOI":"10.1126\/science.1323143"},{"key":"B215","doi-asserted-by":"crossref","first-page":"5187","DOI":"10.4049\/jimmunol.159.11.5187","volume":"159","author":"LEVISETTI M. G.","year":"1997","journal-title":"J. Immunol."},{"key":"B216","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199509270-00001"},{"key":"B217","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.93.7.3031"},{"key":"B218","doi-asserted-by":"publisher","DOI":"10.1084\/jem.178.5.1801"},{"key":"B219","doi-asserted-by":"crossref","first-page":"5658","DOI":"10.4049\/jimmunol.158.12.5658","volume":"158","author":"LIN Y.","year":"1997","journal-title":"J. Immunol."},{"key":"B220","doi-asserted-by":"publisher","DOI":"10.1084\/jem.173.3.721"},{"key":"B221","doi-asserted-by":"publisher","DOI":"10.1084\/jem.174.3.561"},{"key":"B222","doi-asserted-by":"publisher","DOI":"10.1084\/jem.176.6.1595"},{"key":"B224","doi-asserted-by":"publisher","DOI":"10.1172\/JCI118898"},{"key":"B225","doi-asserted-by":"publisher","DOI":"10.1084\/jem.177.6.1643"},{"key":"B226","doi-asserted-by":"publisher","DOI":"10.1126\/science.8202711"},{"key":"B227","first-page":"324","volume":"25","author":"LOWRY R. P.","year":"1993","journal-title":"Transplant. Proc."},{"key":"B228","doi-asserted-by":"publisher","DOI":"10.1096\/fasebj.8.14.7958617"},{"key":"B229","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199712270-00031"},{"key":"B230","doi-asserted-by":"crossref","first-page":"5676","DOI":"10.4049\/jimmunol.158.12.5676","volume":"158","author":"LU L.","year":"1997","journal-title":"J. Immunol."},{"key":"B231","doi-asserted-by":"publisher","DOI":"10.1084\/jem.187.3.427"},{"key":"B232","doi-asserted-by":"publisher","DOI":"10.1016\/1074-7613(94)90106-6"},{"key":"B233","doi-asserted-by":"publisher","DOI":"10.1038\/332040a0"},{"key":"B234","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.94.5.1931"},{"key":"B235","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.93.18.9736"},{"key":"B236","doi-asserted-by":"publisher","DOI":"10.1093\/intimm\/6.6.855"},{"key":"B237","first-page":"1996","volume":"24","author":"MANDEL T. E.","year":"1992","journal-title":"Transplant. Proc."},{"key":"B238","first-page":"216","volume":"24","author":"MANDEL T. E.","year":"1992","journal-title":"Transplant. Proc."},{"key":"B239","doi-asserted-by":"publisher","DOI":"10.1016\/S0041-1345(96)00261-8"},{"key":"B240","first-page":"814","volume":"28","author":"MARKEES T. G.","year":"1996","journal-title":"Transplant. Proc."},{"key":"B242","doi-asserted-by":"publisher","DOI":"10.1016\/S0041-1345(98)00680-0"},{"key":"B243","doi-asserted-by":"publisher","DOI":"10.1172\/JCI2703"},{"key":"B244","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199707270-00026"},{"key":"B245","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199002000-00009"},{"key":"B246","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199612150-00015"},{"key":"B247","doi-asserted-by":"crossref","first-page":"120","DOI":"10.4049\/jimmunol.158.1.120","volume":"158","author":"MARUO S.","year":"1997","journal-title":"J. Immunol."},{"key":"B248","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199506150-00002"},{"key":"B249","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.iy.12.040194.005015"},{"key":"B250","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199407000-00019"},{"key":"B251","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.270.42.24949"},{"key":"B252","first-page":"347","volume":"129","author":"MERRILL J. P.","year":"1978","journal-title":"Ann. Immunol."},{"key":"B253","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1984.03340430064035"},{"key":"B254","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-065X.1993.tb01514.x"},{"key":"B255","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1988.tb36336.x"},{"key":"B256","doi-asserted-by":"publisher","DOI":"10.1016\/S0039-6060(97)90057-X"},{"key":"B257","doi-asserted-by":"publisher","DOI":"10.1093\/intimm\/7.9.1451"},{"key":"B258","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-198904000-00013"},{"key":"B259","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1099-0895(199607)12:2<103::AID-DMR157>3.0.CO;2-2"},{"key":"B261","doi-asserted-by":"crossref","first-page":"2470","DOI":"10.4049\/jimmunol.154.5.2470","volume":"154","author":"MORRIS C. F.","year":"1995","journal-title":"J. Immunol."},{"key":"B263","doi-asserted-by":"publisher","DOI":"10.1038\/362758a0"},{"key":"B264","doi-asserted-by":"publisher","DOI":"10.1016\/0167-5699(96)80606-2"},{"key":"B265","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.iy.07.040189.002305"},{"key":"B266","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199507000-00009"},{"key":"B267","doi-asserted-by":"publisher","DOI":"10.1126\/science.7533326"},{"key":"B268","doi-asserted-by":"publisher","DOI":"10.1016\/0167-5699(95)80069-7"},{"key":"B269","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-197707000-00010"},{"key":"B270","doi-asserted-by":"publisher","DOI":"10.1038\/371250a0"},{"key":"B271","doi-asserted-by":"publisher","DOI":"10.1097\/00002371-199603000-00001"},{"key":"B272","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(98)22009-5"},{"key":"B274","doi-asserted-by":"publisher","DOI":"10.1016\/S0966-3274(96)80043-8"},{"key":"B275","doi-asserted-by":"publisher","DOI":"10.1016\/S0065-2776(08)60755-5"},{"key":"B276","doi-asserted-by":"publisher","DOI":"10.1007\/BF02786391"},{"key":"B277","doi-asserted-by":"publisher","DOI":"10.1016\/0167-5699(92)90068-I"},{"key":"B278","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.89.14.6550"},{"key":"B280","doi-asserted-by":"publisher","DOI":"10.1126\/science.7973690"},{"key":"B281","first-page":"295","volume":"25","author":"ODORICO J. S.","year":"1993","journal-title":"Transplant. Proc."},{"key":"B282","first-page":"370","volume":"112","author":"ODORICO J. S.","year":"1992","journal-title":"Surgery"},{"key":"B283","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199305000-00032"},{"key":"B284","doi-asserted-by":"crossref","first-page":"5185","DOI":"10.4049\/jimmunol.150.11.5185","volume":"150","author":"OHASHI P. S.","year":"1993","journal-title":"J. Immunol."},{"key":"B285","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(91)90164-T"},{"key":"B286","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199212000-00026"},{"key":"B287","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199312000-00046"},{"key":"B288","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199411270-00004"},{"key":"B289","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-198908000-00020"},{"key":"B290","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-198906000-00017"},{"key":"B291","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.271.36.22225"},{"key":"B292","doi-asserted-by":"crossref","first-page":"1944","DOI":"10.4049\/jimmunol.157.5.1944","volume":"157","author":"ONODERA K.","year":"1996","journal-title":"J. Immunol."},{"key":"B293","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(74)93268-1"},{"key":"B294","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199501000-00022"},{"key":"B294a","doi-asserted-by":"publisher","DOI":"10.1126\/science.102.2651.400"},{"key":"B295","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.iy.11.040193.001555"},{"key":"B296","doi-asserted-by":"publisher","DOI":"10.1096\/fasebj.5.13.1916102"},{"key":"B297","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.92.21.9560"},{"key":"B298","doi-asserted-by":"publisher","DOI":"10.1159\/000170203"},{"key":"B299","doi-asserted-by":"crossref","first-page":"499","DOI":"10.4049\/jimmunol.143.2.499","volume":"143","author":"PEARCE N. W.","year":"1989","journal-title":"J. Immunol."},{"key":"B300","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199705270-00016"},{"key":"B301","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199604150-00002"},{"key":"B302","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199457120-00002"},{"key":"B303","doi-asserted-by":"publisher","DOI":"10.1002\/eji.1830240416"},{"key":"B304","doi-asserted-by":"crossref","first-page":"2464","DOI":"10.4049\/jimmunol.158.5.2464","volume":"158","author":"PENG S. L.","year":"1997","journal-title":"J. Immunol."},{"key":"B305","doi-asserted-by":"publisher","DOI":"10.1016\/S1074-7613(00)80284-8"},{"key":"B306","doi-asserted-by":"publisher","DOI":"10.1016\/0003-4975(95)00579-A"},{"key":"B307","doi-asserted-by":"crossref","first-page":"1951","DOI":"10.4049\/jimmunol.157.5.1951","volume":"157","author":"PICCOTTI J. R.","year":"1996","journal-title":"J. Immunol."},{"key":"B309","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199712150-00009"},{"key":"B310","first-page":"301","volume":"25","author":"POSSELT A. M.","year":"1993","journal-title":"Transplant. Proc."},{"key":"B311","doi-asserted-by":"publisher","DOI":"10.1126\/science.2119056"},{"key":"B312","doi-asserted-by":"crossref","first-page":"854","DOI":"10.4049\/jimmunol.144.3.854","volume":"144","author":"POWELL T. J.","year":"1990","journal-title":"J. Immunol."},{"key":"B313","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199205000-00011"},{"key":"B314","doi-asserted-by":"publisher","DOI":"10.1126\/science.8094901"},{"key":"B315","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.4049\/jimmunol.156.4.1325","volume":"156","author":"QUILL H.","year":"1996","journal-title":"J. Immunol."},{"key":"B316","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199408000-00029"},{"key":"B317","doi-asserted-by":"publisher","DOI":"10.1126\/science.1972593"},{"key":"B318","doi-asserted-by":"publisher","DOI":"10.1126\/science.2511629"},{"key":"B319","doi-asserted-by":"publisher","DOI":"10.1084\/jem.177.4.925"},{"key":"B320","doi-asserted-by":"publisher","DOI":"10.1172\/JCI119787"},{"key":"B321","doi-asserted-by":"publisher","DOI":"10.2337\/diab.38.12.1647"},{"key":"B323","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199305000-00013"},{"key":"B324","doi-asserted-by":"publisher","DOI":"10.1084\/jem.180.5.1967"},{"key":"B325","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(91)91368-5"},{"key":"B326","doi-asserted-by":"publisher","DOI":"10.1172\/JCI119396"},{"key":"B327","doi-asserted-by":"publisher","DOI":"10.1016\/0952-7915(94)90018-3"},{"key":"B328","doi-asserted-by":"publisher","DOI":"10.1159\/000236861"},{"key":"B329","doi-asserted-by":"publisher","DOI":"10.1084\/jem.181.3.993"},{"key":"B330","doi-asserted-by":"publisher","DOI":"10.1126\/science.1900951"},{"key":"B331","doi-asserted-by":"crossref","first-page":"3721","DOI":"10.4049\/jimmunol.156.10.3721","volume":"156","author":"ROCK K. L.","year":"1996","journal-title":"J. Immunol."},{"key":"B332","doi-asserted-by":"publisher","DOI":"10.1084\/jem.185.5.825"},{"key":"B333","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.iy.10.040192.002001"},{"key":"B334","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-065X.1989.tb00009.x"},{"key":"B337","doi-asserted-by":"publisher","DOI":"10.1177\/096368979600500109"},{"key":"B339","doi-asserted-by":"publisher","DOI":"10.1084\/jem.177.1.195"},{"key":"B340","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199707150-00032"},{"key":"B341","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199110000-00001"},{"key":"B342","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199110243251708"},{"key":"B343","doi-asserted-by":"publisher","DOI":"10.1016\/0198-8859(90)90025-K"},{"key":"B344","doi-asserted-by":"publisher","DOI":"10.1007\/s001090050145"},{"key":"B345","doi-asserted-by":"publisher","DOI":"10.1084\/jem.181.5.1869"},{"key":"B346","doi-asserted-by":"publisher","DOI":"10.3109\/08830189609061749"},{"key":"B347","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.89.16.7762"},{"key":"B348","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199308000-00040"},{"key":"B349","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199405150-00001"},{"key":"B350","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199712270-00003"},{"key":"B351","first-page":"370","volume":"5","author":"SCHAUB M.","year":"1997","journal-title":"Exp. Nephrol."},{"key":"B352","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(91)90163-S"},{"key":"B353","doi-asserted-by":"publisher","DOI":"10.1002\/eji.1830220704"},{"key":"B354","doi-asserted-by":"publisher","DOI":"10.1126\/science.3285468"},{"key":"B355","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(89)90044-5"},{"key":"B356","doi-asserted-by":"publisher","DOI":"10.1126\/science.2113314"},{"key":"B357","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(05)80055-8"},{"key":"B359","doi-asserted-by":"publisher","DOI":"10.1126\/science.7939690"},{"key":"B360","doi-asserted-by":"publisher","DOI":"10.1038\/376695a0"},{"key":"B361","doi-asserted-by":"publisher","DOI":"10.1002\/eji.1830270711"},{"key":"B362","doi-asserted-by":"publisher","DOI":"10.1002\/eji.1830241019"},{"key":"B363","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199710150-00018"},{"key":"B364","doi-asserted-by":"publisher","DOI":"10.1177\/096368979300200206"},{"key":"B365","doi-asserted-by":"publisher","DOI":"10.2337\/diab.40.11.1430"},{"key":"B367","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199506270-00001"},{"key":"B368","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-065X.1992.tb01421.x"},{"key":"B369","doi-asserted-by":"publisher","DOI":"10.1126\/science.2955518"},{"key":"B370","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199402150-00028"},{"key":"B372","doi-asserted-by":"publisher","DOI":"10.2337\/diab.35.12.1345"},{"key":"B374","doi-asserted-by":"publisher","DOI":"10.1016\/1074-7613(94)90067-1"},{"key":"B375","doi-asserted-by":"publisher","DOI":"10.1084\/jem.185.6.1023"},{"key":"B376","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199708150-00024"},{"key":"B377","doi-asserted-by":"crossref","first-page":"5765","DOI":"10.4049\/jimmunol.158.12.5765","volume":"158","author":"SMYTH M. J.","year":"1997","journal-title":"J. Immunol."},{"key":"B378","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199301000-00025"},{"key":"B379","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-198407000-00015"},{"key":"B380","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.4049\/jimmunol.154.3.1198","volume":"154","author":"SPRENT J.","year":"1995","journal-title":"J. Immunol."},{"key":"B381","doi-asserted-by":"publisher","DOI":"10.1084\/jem.176.6.1543"},{"key":"B382","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199712270-00032"},{"key":"B383","doi-asserted-by":"publisher","DOI":"10.1084\/jem.124.2.127"},{"key":"B384","doi-asserted-by":"publisher","DOI":"10.1016\/0165-6147(93)90212-3"},{"key":"B385","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-5699(96)10070-0"},{"key":"B386","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-198904000-00017"},{"key":"B387","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5347(17)42354-8"},{"key":"B388","doi-asserted-by":"crossref","first-page":"489","DOI":"10.4049\/jimmunol.155.1.489","volume":"155","author":"STEIGER J.","year":"1995","journal-title":"J. Immunol."},{"key":"B389","first-page":"1094","volume":"13","author":"STEINMULLER D.","year":"1981","journal-title":"Transplant. Proc."},{"key":"B390","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.4049\/jimmunol.155.3.1165","volume":"155","author":"STEURER W.","year":"1995","journal-title":"J. Immunol."},{"key":"B391","doi-asserted-by":"crossref","first-page":"3557","DOI":"10.4049\/jimmunol.158.8.3557","volume":"158","author":"STREILEIN J. W.","year":"1997","journal-title":"J. Immunol."},{"key":"B392","doi-asserted-by":"publisher","DOI":"10.1016\/S0198-8859(96)00288-1"},{"key":"B394","doi-asserted-by":"publisher","DOI":"10.1172\/JCI119173"},{"key":"B395","doi-asserted-by":"publisher","DOI":"10.1084\/jem.183.2.693"},{"key":"B396","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199709150-00005"},{"key":"B397","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(94)92583-6"},{"key":"B398","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199103000-00011"},{"key":"B399","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199712270-00035"},{"key":"B400","doi-asserted-by":"publisher","DOI":"10.1084\/jem.183.4.1789"},{"key":"B401","first-page":"80","volume":"97","author":"SUTHERLAND D. E.","year":"1984","journal-title":"Trans. Assoc. Am. Physicians"},{"key":"B403","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-065X.1996.tb00700.x"},{"key":"B404","doi-asserted-by":"publisher","DOI":"10.1038\/351150a0"},{"key":"B405","doi-asserted-by":"publisher","DOI":"10.1096\/fasebj.10.7.8635689"},{"key":"B406","doi-asserted-by":"publisher","DOI":"10.1084\/jem.185.5.817"},{"key":"B407","doi-asserted-by":"crossref","first-page":"2964","DOI":"10.1182\/blood.V81.11.2964.2964","volume":"81","author":"TAGA K.","year":"1993","journal-title":"Blood"},{"key":"B408","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(94)90375-1"},{"key":"B409","doi-asserted-by":"publisher","DOI":"10.1084\/jem.177.1.165"},{"key":"B410","first-page":"863","volume":"22","author":"TERAOKA S.","year":"1990","journal-title":"Transplant. Proc."},{"key":"B411","doi-asserted-by":"publisher","DOI":"10.2337\/diab.35.1.83"},{"key":"B412","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199501270-00017"},{"key":"B413","doi-asserted-by":"publisher","DOI":"10.1016\/S1074-7613(00)80366-0"},{"key":"B414","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.86.4.1333"},{"key":"B415","doi-asserted-by":"publisher","DOI":"10.1016\/1074-7613(95)90125-6"},{"key":"B416","doi-asserted-by":"crossref","first-page":"5091","DOI":"10.4049\/jimmunol.158.11.5091","volume":"158","author":"TIVOL E. A.","year":"1997","journal-title":"J. Immunol."},{"key":"B417","doi-asserted-by":"publisher","DOI":"10.1016\/S0952-7915(96)80011-2"},{"key":"B418","doi-asserted-by":"crossref","first-page":"2232","DOI":"10.4049\/jimmunol.159.5.2232","volume":"159","author":"TRAN H. M.","year":"1997","journal-title":"J. Immunol."},{"key":"B419","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.iy.12.040194.000505"},{"key":"B420","doi-asserted-by":"publisher","DOI":"10.1038\/380284a0"},{"key":"B421","first-page":"2183","volume":"27","author":"TUCH B. E.","year":"1995","journal-title":"Transplant. Proc."},{"key":"B422","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.89.22.11102"},{"key":"B423","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199607270-00014"},{"key":"B424","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199311000-00039"},{"key":"B425","doi-asserted-by":"publisher","DOI":"10.1159\/000237614"},{"key":"B426","doi-asserted-by":"publisher","DOI":"10.1002\/eji.1830200232"},{"key":"B427","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-196801000-00002"},{"key":"B428","first-page":"380","volume":"27","author":"VOSSEN A. C.","year":"1995","journal-title":"Transplant. Proc."},{"key":"B429","doi-asserted-by":"publisher","DOI":"10.1084\/jem.177.5.1359"},{"key":"B430","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.4049\/jimmunol.151.2.1147","volume":"151","author":"WALTENBERGER J.","year":"1993","journal-title":"J. Immunol."},{"key":"B431","doi-asserted-by":"publisher","DOI":"10.1002\/eji.1830240714"},{"key":"B432","doi-asserted-by":"publisher","DOI":"10.1016\/0966-3274(94)90036-1"},{"key":"B433","doi-asserted-by":"publisher","DOI":"10.1038\/356314a0"},{"key":"B435","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(90)90420-J"},{"key":"B436","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-5699(97)01151-1"},{"key":"B437","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.med.48.1.341"},{"key":"B438","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-5699(97)01053-0"},{"key":"B439","first-page":"1217","volume":"371","author":"WEINER H. L.","year":"1995","journal-title":"Adv. Exp. Med. Biol."},{"key":"B440","doi-asserted-by":"publisher","DOI":"10.1084\/jem.187.12.2037"},{"key":"B441","doi-asserted-by":"publisher","DOI":"10.1016\/0923-2494(96)87179-3"},{"key":"B442","doi-asserted-by":"publisher","DOI":"10.1002\/eji.1830240435"},{"key":"B443","doi-asserted-by":"crossref","first-page":"2942","DOI":"10.4049\/jimmunol.134.5.2942","volume":"134","author":"WILLIAMS I. R.","year":"1985","journal-title":"J. Immunol."},{"key":"B444","doi-asserted-by":"crossref","first-page":"153","DOI":"10.4049\/jimmunol.156.1.153","volume":"156","author":"WILLIAMS N. S.","year":"1996","journal-title":"J. Immunol."},{"key":"B445","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199511270-00018"},{"key":"B446","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-5699(96)10069-4"},{"key":"B447","doi-asserted-by":"publisher","DOI":"10.3109\/08830189209053515"},{"key":"B448","doi-asserted-by":"publisher","DOI":"10.1084\/jem.185.7.1327"},{"key":"B449","doi-asserted-by":"publisher","DOI":"10.1084\/jem.178.5.1789"},{"key":"B450","doi-asserted-by":"publisher","DOI":"10.1038\/379682a0"},{"key":"B451","doi-asserted-by":"publisher","DOI":"10.1615\/CritRevImmunol.v14.i3-4.50"},{"key":"B452","doi-asserted-by":"crossref","first-page":"6339","DOI":"10.4049\/jimmunol.154.12.6339","volume":"154","author":"YIN D.","year":"1995","journal-title":"J. Immunol."},{"key":"B453","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.immunol.14.1.369"},{"key":"B454","doi-asserted-by":"publisher","DOI":"10.1038\/303625a0"},{"key":"B455","doi-asserted-by":"publisher","DOI":"10.1016\/S0041-1345(96)00552-0"},{"key":"B456","doi-asserted-by":"publisher","DOI":"10.1097\/00007890-199409000-00008"},{"key":"B457","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.88.22.10252"},{"key":"B458","doi-asserted-by":"crossref","first-page":"2489","DOI":"10.4049\/jimmunol.145.8.2489","volume":"145","author":"ZHANG Z. J.","year":"1990","journal-title":"J. Immunol."},{"key":"B459","doi-asserted-by":"publisher","DOI":"10.1038\/377348a0"},{"key":"B460","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.4049\/jimmunol.159.3.1169","volume":"159","author":"ZHENG X. X.","year":"1997","journal-title":"J. Immunol."}],"container-title":["Physiological Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.physiology.org\/doi\/pdf\/10.1152\/physrev.1999.79.1.99","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,30]],"date-time":"2023-08-30T06:11:35Z","timestamp":1693375895000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.physiology.org\/doi\/10.1152\/physrev.1999.79.1.99"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,1,1]]},"references-count":429,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1999,1,1]]}},"alternative-id":["10.1152\/physrev.1999.79.1.99"],"URL":"https:\/\/doi.org\/10.1152\/physrev.1999.79.1.99","relation":{},"ISSN":["0031-9333","1522-1210"],"issn-type":[{"value":"0031-9333","type":"print"},{"value":"1522-1210","type":"electronic"}],"subject":[],"published":{"date-parts":[[1999,1,1]]}}}