{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T01:37:15Z","timestamp":1768268235855,"version":"3.49.0"},"reference-count":0,"publisher":"American Physiological Society","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American Journal of Physiology-Legacy Content"],"published-print":{"date-parts":[[1975,12,1]]},"abstract":"<jats:p> Recent studies proposed that [2T]glucose is preferable to [14C]-glucose as a tracer for the measurement of glucose turnover. However, higher values for glucose turnover were obtained using [2T]glucose than with [14C]glucose. The present study explores the merit of another species of tritiated glucose, [3T]glucose. Utilizing isotope-dilution principles, comparison is made of glucose turnover values determined by use of [2T]glucose, [3T]glucose, and [6-14C]glucose. Glucose turnover using [2T]glucose was 1.51 +\/- 0.07 times greater than that using [6-14C]glucose, after correction for recycling of 14C. However, glucose turnover values obtained with [3T]glucose were similar to those obtained with [6-14C]glucose. There were no temporal or quantitative differences in appearance of tritium (T) in plasma water after injection of [2T]- and [3T]glucose. A methylprednisolone regimen in the normal dog increased glucose turnover as determined by all three tracers, but the increase observed using [2T]glusoce was significantly greater than that using that two other tracers. Thiement for [6-14C]glucose for measurement of glucose turnover in the dog. <\/jats:p>","DOI":"10.1152\/ajplegacy.1975.229.6.1662","type":"journal-article","created":{"date-parts":[[2017,12,23]],"date-time":"2017-12-23T09:19:46Z","timestamp":1514020786000},"page":"1662-1667","source":"Crossref","is-referenced-by-count":90,"title":["Glucose turnover values in the dog obtained with various species of labeled glucose"],"prefix":"10.1152","volume":"229","author":[{"given":"N","family":"Altszuler","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Barkai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C","family":"Bjerknes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B","family":"Gottlieb","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Steele","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"24","container-title":["American Journal of Physiology-Legacy Content"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.physiology.org\/doi\/pdf\/10.1152\/ajplegacy.1975.229.6.1662","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,8]],"date-time":"2019-09-08T20:20:36Z","timestamp":1567974036000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.physiology.org\/doi\/10.1152\/ajplegacy.1975.229.6.1662"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1975,12,1]]},"references-count":0,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1975,12,1]]}},"alternative-id":["10.1152\/ajplegacy.1975.229.6.1662"],"URL":"https:\/\/doi.org\/10.1152\/ajplegacy.1975.229.6.1662","relation":{},"ISSN":["0002-9513"],"issn-type":[{"value":"0002-9513","type":"print"}],"subject":[],"published":{"date-parts":[[1975,12,1]]}}}